The city of Washington, District Of Columbia, currently has 13 active clinical trials seeking participants for Pain research studies.
Natural History of Sickle Cell Disease
Recruiting
This study is not a treatment protocol and no experimental treatments are involved. Study participants may be seen as needed for clinical, translational and basic research studies, or as medically indicated. Subjects will receive their general medical care outside the NIH and will be seen at our clinic or at CNHS with varying frequency. Subjects may be seen for multiple visits. Subjects may be asked to return for additional testing as needed. Clinical care for patients with sickle cell disease w... Read More
Gender:
All
Ages:
Between 2 years and 90 years
Trial Updated:
06/19/2024
Locations: Childrens National Health Center, Washington, District of Columbia
Conditions: Pain Crisis
Focused Ultrasound for the Complex Patient
Recruiting
The goal of this clinical trial is to to inhibit the anterior insula (AI) with low intensity focused ultrasound (LIFU) to determine the causal role for the AI in pain processing, anxiety, and opiate cue-induced craving. The main question[s] it aims to answer are: the safety and tolerability of LIFU delivered bilaterally to AI compared to sham stimulation in individuals with opiate use disorder (OUD), anxiety, and chronic back pain the effects of LIFU vs sham on measures of pain processing, anxi... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
06/05/2024
Locations: Washington DC Veterans Affairs Medical Center, Washington, District of Columbia
Conditions: Opioid Use Disorder, Chronic Back Pain, Anxiety
A Phase 2 Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome
Recruiting
The aim of this study is to assess whether IW-3300 is safe and works for the treatment of interstitial cystitis/bladder pain syndrome (IC/BPS). The main question the study aims to answer is whether IW-3300 helps bladder pain and other symptoms (for example, bladder burning, pressure and discomfort). Subjects will be assigned to receive either the study drug or placebo by chance.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/30/2024
Locations: MedStar Washington Hospital Center, Washington, District of Columbia
Conditions: Interstitial Cystitis, Bladder Pain Syndrome
Augmented Reality For MRI-Guided Interventions
Recruiting
The purpose of this study is to determine feasibility and safety of using an augmented reality system in patients undergoing MRI-Guided needle procedures.
Gender:
All
Ages:
Between 3 years and 21 years
Trial Updated:
01/24/2024
Locations: Children's National Hospital, Washington, District of Columbia
Conditions: Infections, Pain, Diagnosis, Image Guided Needle Biopsy
PVB vs Ketamine/Lidocaine in Rib Fracture Patients
Recruiting
Rib fractures are a common admission to the trauma service. The mainstay of treatment is pain control to improve respiratory effort in order to offset the risk of pneumonia and mechanical ventilation. In addition to standard pain control modalities, the investigator's institution utilizes paravertebral blocks as well as lidocaine and ketamine infusions for pain control. The current standard of care for pain control is to begin with acetaminophen, ibuprofen or celecoxib and opioids with the addit... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/05/2024
Locations: The George Washington University Hospital, Washington, District of Columbia
Conditions: Rib Fractures, Rib Trauma, Rib Fracture Multiple, Pain, Acute
Comparison of Qutenza (8% Capsaicin) With a Low-dose Capsaicin for Treatment of Nerve Pain After Surgery
Recruiting
This is an interventional, Phase III, double-blind, randomized, controlled, parallel-group, multi-site, clinical trial to confirm the efficacy and safety of repeated topical application of Qutenza (capsaicin 8% topical system) versus low-dose capsaicin control (capsaicin 0.04% topical system) in subjects with moderate to severe postsurgical neuropathic pain (PSNP).
Gender:
All
Ages:
18 years and above
Trial Updated:
12/05/2023
Locations: International Spine, Pain, and Performance Center, Washington, District of Columbia
Conditions: Post Surgical Neuropathic Pain
Intraperitoneal Infusion of Analgesic for Postoperative Pain Management
Recruiting
The study is a prospective, double-blinded, placebo-controlled multi-center trial to measure if postoperative pain and the amount of narcotics used are reduced by a clinically significant amount in women undergoing minimally invasive hysterectomy receiving a continuous infusion of intraperitoneal (IP) local anesthetic (LA) or a continuous infusion of LA combined with an NSAID compared with a control group who receives only 0.9% normal saline.
Gender:
Female
Ages:
Between 18 years and 65 years
Trial Updated:
11/06/2023
Locations: MedStar Washington Hospital Center, Washington, District of Columbia +1 locations
Conditions: Hysterectomy, Gynecologic Surgical Procedures, Narcotic Use, Pain, Postoperative
SPR PNS for Chronic Shoulder Pain
Recruiting
The purpose of this research is to gather post-market data regarding the effectiveness of the SPRINT Peripheral Nerve Stimulation (PNS) System for the treatment of chronic shoulder pain due to chronic degenerative changes of your shoulder. The System delivers mild electrical stimulation to the muscles in your shoulder. The System includes up to two leads (small wires) that are placed through your skin into your shoulder. The leads attach to a device worn on your body that deliver stimulation (ca... Read More
Gender:
All
Ages:
Between 21 years and 100 years
Trial Updated:
09/26/2023
Locations: International Spine Pain & Performance Center, Washington, District of Columbia
Conditions: Shoulder Pain, Shoulder Injuries, Shoulder Arthritis
Transvaginal Low-level Laser Therapy to Improve Pelvic Pain and Sexual Function in Patients With Endometriosis.
Recruiting
Dyspareunia is defined as pain with penetrative sexual intercourse. Women with endometriosis have a nine-fold increased risk of dyspareunia, when compared to the general female population. A prospective single-blinded randomized controlled trial will be performed evaluating the change in pelvic pain and sexual satisfaction scores from baseline to 6 weeks after treatment with transvaginal photobiomodulation therapy or sham therapy. Treatment will involve 9 planned treatment sessions over 3-4 wee... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
09/01/2023
Locations: MedStar Washington Hospital Center, Washington, District of Columbia +2 locations
Conditions: Endometriosis, Dyspareunia, Pelvic Pain
Clinical Study Of a Micro-Implantable Pulse Generator For The Treatment of Peripheral Neuropathic Pain
Recruiting
This post market study is being conducted to document the comparative effectiveness and safety of peripheral nerve stimulation plus conventional medical management versus conventional medical management alone in the treatment of chronic, intractable peripheral neuralgia of post-traumatic or post-surgical origin. This is a prospective, minimal risk, multi-center, randomized control trial.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/13/2023
Locations: International Spine, Pain and Performance Center, Washington, District of Columbia
Conditions: Peripheral Neuralgia, Chronic Pain
Measuring Analgesic Interventions
Recruiting
It is generally recognized that pain assessment and management especially in newborns, children and other nonverbal populations is an unmet need. According to the American Medical Association, "the pediatric population is at risk of inadequate pain management, with age-related factors affecting pain management in children. Children are often given minimal or no analgesia for procedures that would routinely be treated aggressively in adults. Although much is now known about pain management in chi... Read More
Gender:
All
Ages:
Between 7 years and 21 years
Trial Updated:
01/31/2023
Locations: Children's National Health System, Washington, District of Columbia
Conditions: Pain
Trigger Point Injections in Anterior Cervical Surgery
Recruiting
To achieve appropriate exposure for an anterior neck surgery (for example an Anterior Cervical Discectomy and Fusion or ACDF), patients are positioned supine with their neck extended. Due to being in this position, patients frequently complain of posterior neck stiffness and pain postoperatively in addition to the anterior incisional pain. This posterior cervical pain can be classified as myofascial pain. Cervical myofascial pain is thought to be the result of overuse or trauma to the supportin... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/07/2022
Locations: George Washington University Hospital, Washington, District of Columbia
Conditions: Myofacial Pain, Pain, Neck, Pain, Back, Cervical Fusion