There are currently 9 active clinical trials seeking participants for Acne research studies. The states with the highest number of trials for Acne participants are California, Texas, Florida and Michigan.
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
NCT06316297
Recruiting
The purpose of the trial is to evaluate the safety, efficacy and immunogenicity of up to 3 intramuscular injections of the Acne mRNA vaccine candidate at up to three dose levels in adult participants aged 18 to 45 years with moderate to severe acne.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
08/04/2025
Locations: Core Healthcare Group- Site Number : 8400067, Cerritos, California +36 locations
Conditions: Acne
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Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne
NCT07013747
Recruiting
The purpose of the VBE00009 study is to evaluate the safety, efficacy and immunogenicity of 2 administrations of the Acne mRNA vaccine candidate at single dose level in participants aged 18 to 45 years with mild acne. This study will consist of a Sentinel Cohort and a Main Cohort, with the Sentinel Cohort assessing the safety in a stepwise manner.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
08/04/2025
Locations: Encino Research Center- Site Number : 8400008, Encino, California +3 locations
Conditions: Acne
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Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne
NCT04582383
Recruiting
Acne is common illness of adolescents and young adults which is associated with substantial morbidity. While topical treatments are often sufficient for mild acne, moderate to severe acne often requires treatment with systemic medications such as oral antibiotics, hormonal therapies such spironolactone, and isotretinoin. Sebum overproduction is fundamental to the pathogenesis of acne with associated disordered keratinization and subsequent microbial colonization and inflammation resulting in the... Read More
Gender:
FEMALE
Ages:
Between 16 years and 40 years
Trial Updated:
05/27/2025
Locations: Johnson Dermatology, Fort Smith, Arkansas +17 locations
Conditions: Acne
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Experience With Topical Acne Treatment
NCT05582434
Recruiting
Acne is a chronic condition that typically requires the use of multiple medications.1 Medication adherence is especially challenging for patients with chronic diseases and often decreases over time, especially for those using topical medications.1 Nonadherence can result in multiple negative effects including treatment failure, increased healthcare costs, and decreased quality of life. Primary nonadherence refers to problems acquiring and starting treatment. Challenges to this form of nonadheren... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
05/27/2025
Locations: Wake Forest University Health Sciences, Winston-Salem, North Carolina
Conditions: Acne
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Phase 1 Study to Evaluate the Safety, Tolerability, PK, and PD of TVB-3567 in Healthy Participants With or Without Acne
NCT06989840
Recruiting
This is a 4-part study. Part A will be a randomized, double-blind, placebo-controlled investigation of single ascending doses (SAD) to assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamic (PD) biomarkers of TVB-3567 administered orally in healthy participants. Part B will be a randomized, open-label, 2-way crossover investigation to assess the effect of food on a single dose TVB-3567 administered orally in healthy participants. Parts C and D will be randomized, double-blin... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
05/16/2025
Locations: Celerion, Inc., Tempe, Arizona
Conditions: Acne
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AVAVA MIRIA General Use
NCT06868615
Recruiting
A general protocol to treat a variety of dermatologic conditions and collect patient feedback. Primary outcome is the collection and analysis of patient questionnaires related to the overall experience of the device treatment. Secondary outcome measures include physician and subject evaluations in regards to improvement seen in the device as well as assessment of side effects.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
03/06/2025
Locations: AVAVA, Inc., Waltham, Massachusetts
Conditions: Acne, Acne Scars - Mixed Atrophic and Hypertrophic, Scars, Wrinkle, Pigment; Lesion, Skin Texture Disorder
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The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis
NCT05942248
Recruiting
The study is conducted to determine if image-based computer grading can of acne, melasma, rosacea and seborrheic dermatitis correlate well to expert based clinical severity grading.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/26/2024
Locations: Integrative Skin and Research, Sacramento, California
Conditions: Acne, Melasma, Rosacea, Seborrheic Dermatitis
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Single-Blind Study Assessing the Use of a Topical Antioxidant With A Series of Laser Procedures to Reduce Sebum Production
NCT06376110
Recruiting
This is a split-face, single-blind study assessing the use of an antioxidant serum with a series of acne laser treatments to reduce sebum production in healthy male and female subjects between the ages of 18 and 65 years, inclusive, with Fitzpatrick skin types I-VI.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/14/2024
Locations: Austin Institute for Clinical Research, Inc., Pflugerville, Texas
Conditions: Acne
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Study of Skin Balancing Gel Cream Safety and Influence of Skin Microbiome on Acne Prone Skin
NCT05941065
Recruiting
The purpose of this study is to assess the safety of the skin balancing gel cream and examine the effects it has on the skin microbiome of individuals with non-cystic acne prone skin.
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
10/06/2023
Locations: Integrative Skin and Research, Sacramento, California
Conditions: Skin Microboime, Acne
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