There are currently 6 active clinical trials seeking participants for Bronchiectasis research studies. The states with the highest number of trials for Bronchiectasis participants are Florida, Texas, California and New South Wales.
Natural History of Bronchiectasis
NCT00943514
Recruiting
Background: * Bronchiectasis is a disease characterized by airways that are inflamed, abnormally dilated, and chronically infected. Individuals with bronchiectasis have a history of chronic and recurring respiratory infections. Depending on the underlying cause, these infections may involve the entire respiratory tract, resulting in sinus, ear, and lung disease. * Bronchiectasis continues to be a significant problem in developing countries and in specific groups of individuals, particularly in... Read More
Gender:
ALL
Ages:
Between 5 years and 100 years
Trial Updated:
07/09/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Bronchiectasis, Cystic Fibrosis, Autoimmune Disease, Common Variable Immunodeficiency
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The AIRTIVITY® Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis
NCT06872892
Recruiting
This study is open to adults with bronchiectasis. People can participate in this study if they produce sputum and have had flare-ups (also called exacerbations). The purpose of this study is to find out whether a medicine called BI 1291583 helps people with bronchiectasis. Participants are put into 2 groups randomly, which means by chance. One group takes BI 1291583 tablets and the other group takes placebo tablets. A placebo tablet looks like the BI 1291583 tablet but does not contain any medi... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/08/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama +461 locations
Conditions: Bronchiectasis
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Evaluation Of The Lung Microbiome In NTM Bronchiectasis
NCT02779478
Recruiting
A biomarker cohort study design is proposed to study whether specific airway microbiota alterations are associated with pulmonary Non-tuberculous mycobacteria (NTM) disease. In a cohort of 200 subjects suspected of having pulmonary NTM disease, the investigators will evaluate the airway microbiome using an aliquot of the induced sputum and upper airway samples. Since induced sputum may reflect different regions of the upper/lower airways, the investigators will evaluate the upper and lower airwa... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/29/2025
Locations: New York University School of Medicine, New York, New York
Conditions: Nontuberculous Mycobacteria, Bronchiectasis
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Hypertonic Saline in NCFB
NCT06242795
Recruiting
The purpose of this single arm clinical trial is to evaluate the effects of 7% hypertonic saline (HS) delivered by nebulizer on clearance of mucus from the lungs in people with bronchiectasis (dilated airways) not due to cystic fibrosis. Mucociliary clearance (MCC) to measure the rate at which a person's lungs can clear inhaled particles will be assessed at baseline, and after acute (single dose) HS treatment, as well as after two weeks of treatment with HS. The study has two main questions: 1... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/21/2025
Locations: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Conditions: Bronchiectasis, Non-cystic Fibrosis Bronchiectasis
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Acoustic Waveform Respiratory Evaluation
NCT06512064
Recruiting
The study will evaluate the feasibility of using smartphone speakers and microphones to evaluate the caliber of the airways, detect airway obstruction, aid in airway disease diagnosis, and identify disease exacerbations.
Gender:
ALL
Ages:
Between 8 years and 65 years
Trial Updated:
09/11/2024
Locations: Indiana University, Indianapolis, Indiana +1 locations
Conditions: Asthma, COPD, Cystic Fibrosis, Ciliary Motility Disorders, Bronchiectasis, Airway Malacia, Healthy Control
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Telehealth and Onsite Maintenance Exercise in Chronic Lung Disease
NCT06304207
Recruiting
The goal of this pilot clinical trial is to compare telehealth and onsite supervised maintenance exercise program for adults with Chronic Lung Disease. The specific aims of the study are: * To compare 8-week supervised maintenance program delivered onsite and via tele-rehab with no maintenance for patients with Chronic Lung Disease following discharge from traditional exercise or physical therapy or onsite outpatient rehabilitation programs on clinical outcomes (dyspnea, exercise capacity, phy... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
07/30/2024
Locations: MGH Institute of Health Professions, Charlestown, Massachusetts
Conditions: Copd, COPD Exacerbation, COPD Bronchitis, Emphysema or COPD, Chronic Lung Disease, Pulmonary Fibrosis, Interstitial Lung Disease, Bronchiectasis, Chronic Asthma, Chronic Asthmatic Bronchitis
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