There are currently 4 active clinical trials seeking participants for Gastroesophageal Reflux Disease research studies. The states with the highest number of trials for Gastroesophageal Reflux Disease participants are California, Florida, Texas and North Carolina.
Domperidone in Treating Patients with Gastrointestinal Disorders
NCT01696734
Recruiting
This phase III trial studies how well domperidone works in treating patients with gastrointestinal disorders. Domperidone may help control chronic gastrointestinal disorders and their symptoms, such as pain, bloating, and nausea and vomiting, by stimulating contraction of the stomach to increase its ability to empty itself of food.
Gender:
ALL
Ages:
16 years and above
Trial Updated:
02/03/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Digestive System Disorder, Dyspepsia, Esophagitis, Gastroesophageal Reflux Disease, Gastroparesis, Heartburn, Nausea and Vomiting
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Outcomes After Medical and Surgical Treatment of Gastroesophageal Reflux Disease
NCT00260572
Recruiting
The aims of this study are to create a prospective data base to evaluate the long term outcomes of medical and surgical treatment of gastroesophageal reflux disease (GERD); to measure standard outcomes as well as patient derived outcomes such as general and disease specific quality of life (QOL) issues and patient satisfaction; to refine the parameters that may identify patients who will benefit from surgery for GERD; and to identify possible determinants of failure of both medical and surgical... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/04/2025
Locations: UPMC Department of Cardiothoracic Surgery, Pittsburgh, Pennsylvania
Conditions: Gastroesophageal Reflux Disease
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GCC Agonist Signal in the Small Intestine
NCT05107219
Recruiting
This early phase I trial studies the guanylyl cyclase C (GCC) agonist effect on cGMP signal in duodenal tissue. Plecanatide and linaclotide are drugs approved by the Food and Drug Administration for the treatment of conditions related to constipation. This trial aims to see the effects of taking either one of two drugs, plecanatide or linaclotide, or no drug, on a certain chemical found in the tissue collected from small intestine and how they compare.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/16/2024
Locations: Mayo Clinic in Arizona, Scottsdale, Arizona +3 locations
Conditions: Barrett Esophagus, Gastroesophageal Reflux Disease, Malignant Digestive System Neoplasm
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Progression of Gastroesophageal Reflux Disease and Barrett's Esophagus and the Creation of a Barrett's Registry
NCT00574327
Recruiting
The purpose of this study is to determine or evaluate the risk factors such as smoking, family history etc. that cause esophageal cancer and to determine the genetic changes that lead to esophageal cancer. The investigators hypothesis is that systematic collection of data on the natural history of GERD and BE patients and risk factors for development of BE in patients with chronic GERD and progression of BE to dysplasia and adenocarcinoma will provide useful information to develop a decision mod... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/15/2023
Locations: Department of Veterans Affairs Medical Center, Kansas City, Missouri
Conditions: Barrett's Esophagus, Gastroesophageal Reflux Disease, Esophageal Adenocarcinoma
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