There are currently 1309 clinical trials in Atlanta, Georgia looking for participants to engage in research studies. Trials are conducted at various facilities, including Emory University, Emory University Hospital, Emory University Hospital/Winship Cancer Institute and Children's Healthcare of Atlanta. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Tolinapant and Radiation for Cisplatin-Ineligible, Previously Untreated, Locally Advanced Head and Neck Cancer
NCT05245682
Recruiting
This early-phase trial tests the safety and side effects of a tolinapant given together with radiation therapy in treating patients with head and neck cancer for which the patient has not received treatment in the past (previously untreated), has spread to nearby tissue or lymph nodes (locally advanced) and cannot receive cisplatin (cisplatin-ineligible). Tolinapant may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Radiation therapy uses high energy x-ray... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: Emory University/Winship Cancer Institute, Atlanta, Georgia
Conditions: Head and Neck Carcinoma of Unknown Primary, Locally Advanced Head and Neck Squamous Cell Carcinoma, Locally Advanced Hypopharyngeal Squamous Cell Carcinoma, Locally Advanced Laryngeal Squamous Cell Carcinoma, Locally Advanced Nasopharyngeal Squamous Cell Carcinoma, Locally Advanced Oropharyngeal Squamous Cell Carcinoma
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Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
NCT01574053
Recruiting
Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America. More than 30,000 participants have now enrolled into the study. With annual assessments and no end date, Enroll-HD has built a large and rich database of longitudinal clinical data and biospecimens that form the basis for studies developing tools and b... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: Emory University, Wesley Woods Health Center, Atlanta, Georgia
Conditions: Huntington's Disease
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Arginine Replacement Therapy in COVID-19
NCT05855330
Recruiting
The purpose of this study is to investigate if receiving doses of arginine (a protein in the body) will improve mitochondria function in children with COVID-19. The study will be performed in Children's Healthcare of Atlanta, Egleston campus. Patients will be randomized to receive one of three doses of arginine three times a day for five days or at discharge whichever comes first.
Gender:
All
Ages:
Between 3 years and 21 years
Trial Updated:
02/26/2024
Locations: Children's Healthcare of Atlanta (CHOA), Egleston, Atlanta, Georgia
Conditions: COVID-19
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SG2501 Safety Study in Subjects With Relapsed or Refractory Hematological Malignancies and Lymphoma.
NCT05293912
Recruiting
This is a phase Ia/Ib, first-in-Human, open-Label, multicenter, dose escalation and dose expansion study designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary efficacy of SG2501 in subjects with relapsed or refractory hematological malignancies and lymphoma.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/23/2024
Locations: Northside Hospital, Atlanta, Georgia
Conditions: Hematological Malignancy, Lymphoma
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Development and Testing of a Pediatric Cervical Spine Injury Risk Assessment Tool
NCT05049330
Recruiting
Cervical spine injuries (CSI) are serious, but rare events in children. Spinal precautions (rigid cervical collar and immobilization on a longboard) in the prehospital setting may be beneficial for children with CSI, but are poorly studied. In contrast, spinal precautions for pediatric trauma patients without CSI are common and may be associated with harm. Spinal precautions result in well-documented adverse physical and physiological sequelae. Of substantial concern is that the mere presence of... Read More
Gender:
All
Ages:
18 years and below
Trial Updated:
02/21/2024
Locations: Children's Healthcare of Atlanta, Atlanta, Georgia
Conditions: Cervical Spine Injury
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The Tether™ - Vertebral Body Tethering System Post Approval Study
NCT04505579
Recruiting
This study is an opportunity to provide continued reasonable assurance of the safety and probable benefit of The Tether HUD. The study will collect long term safety and efficacy information from patients who have had their idiopathic scoliosis treated via anterior vertebral body tethering (AVBT) with The Tether.
Gender:
All
Ages:
All
Trial Updated:
02/21/2024
Locations: Children's Healthcare of Atlanta, Atlanta, Georgia
Conditions: Scoliosis Idiopathic
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A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome
NCT05163314
Recruiting
The main aim of the study is to learn if soticlestat, when given as an add-on therapy, reduces the number of seizures in children and adults with Dravet Syndrome (DS) or Lennox-Gastaut Syndrome (LGS). Participants will receive their standard anti-seizure therapy, plus tablets of soticlestat. There will be scheduled visits and follow-up phone calls throughout the study.
Gender:
All
Ages:
Between 2 years and 56 years
Trial Updated:
02/20/2024
Locations: Clinical Integrative Research Center of Atlanta, Atlanta, Georgia
Conditions: Dravet Syndrome (DS), Lennox Gastaut Syndrome (LGS)
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A Mobile Application for Child-focused Perioperative Education
NCT06054282
Recruiting
The investigators developed a child-friendly mobile application to support accessible, interactive patient/caregiver education about pediatric tonsillectomy. This randomized controlled trial aims to evaluate whether the intervention reduces preoperative anxiety, improves patients' confidence and positive coping, improves caregivers' satisfaction and self-efficacy, and reduces call volumes from caregivers to the clinic after surgery compared to current standard care.
Gender:
All
Ages:
Between 5 years and 13 years
Trial Updated:
02/20/2024
Locations: Children's Healthcare of Atlanta, Atlanta, Georgia
Conditions: Preoperative Anxiety
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ELUCIDATE FFRct Study
NCT06018194
Recruiting
The goal of this study is to evaluate the diagnostic accuracy of a novel plaque-based coronary CT angiography (CCTA) fractional flow reserve (FFRct) software device for the estimation of invasive fractional flow reserve (FFR). Researchers will compare the Elucid plaque-based FFRct analysis to invasively measured FFR in patients who have previously undergone CCTA and invasively assessed FFR.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/15/2024
Locations: Piedmont Healthcare, Atlanta, Georgia
Conditions: Coronary Artery Disease
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Rectal Insert TAF/EVG Pre-Exposure Prophylaxis (RITE PrEP) Study
NCT06274398
Recruiting
This is a double-blind, placebo-controlled, randomized two-phase study to evaluate the safety and pharmacokinetics (PK) of two TAF/EVG inserts administered rectally for 3 consecutive days, then every other day for 14 days.
Gender:
All
Ages:
Between 18 years and 59 years
Trial Updated:
02/15/2024
Locations: Emory Clinic, Atlanta, Georgia
Conditions: Safety Issues
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A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH
NCT04764474
Recruiting
An open label single-arm clinical trial to evaluate the safety, tolerability, PK, PD, and preliminary efficacy of HMPL-306 in subjects with advanced relapsed, refractory, or resistant hematological malignancies that harbor IDH mutations.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/13/2024
Locations: Winship Cancer Institute - Emory University, Atlanta, Georgia
Conditions: Isocitrate Dehydrogenase Gene Mutation
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Opioid-Free Orthopaedics
NCT04659317
Recruiting
The goal of this investigation is to compare effectiveness of this multimodal regimen at controlling postoperative pain with and without the use of opioid medications.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/09/2024
Locations: The Emory Clinic, Atlanta, Georgia +1 locations
Conditions: Pain, Pain, Postoperative
Register for Updates