The state of Georgia currently has 7 active clinical trials seeking participants for Epilepsy research studies. These trials are conducted in various cities, including Atlanta, Augusta, Decatur and Savannah.
RNS System LGS Feasibility Study
Recruiting
To generate preliminary safety and effectiveness data for brain-responsive neurostimulation of thalamocortical networks as an adjunctive therapy in reducing the frequency of generalized seizures in individuals 12 years of age or older with Lennox Gastaut Syndrome (LGS) who are refractory to antiseizure medications. The intent is to determine the feasibility and the optimal design of a subsequent pivotal study in order to expand the indication for use for the RNS System as a treatment for patien... Read More
Gender:
All
Ages:
12 years and above
Trial Updated:
02/08/2024
Locations: Emory University, Atlanta, Georgia
Conditions: Epilepsy, Lennox Gastaut Syndrome, Lennox-Gastaut Syndrome, Intractable, Seizures, Seizures, Generalized
Randomized, Double-Blind Study to Evaluate Efficacy and Safety of Cenobamate Adjunctive Therapy in PGTC Seizures
Recruiting
This trial is intended to study the safety and effectiveness of an new anti-epileptic drug (AED) on Primary Generalized Tonic-Clonic (PGTC) Seizures. Eligible Subjects, adults and adolescents, will continue to take their usual AEDs and receive either cenobamate or placebo. Subjects will have a 50% chance or receiving cenobamate or placebo (sugar pill). Subjects will initially receive 12.5 mg of cenobamate or placebo (study drug) and increase the dose every two weeks until they reach a target dos... Read More
Gender:
All
Ages:
12 years and above
Trial Updated:
02/08/2024
Locations: Clinical Integrative Research Center of Atlanta, CIRCA, Atlanta, Georgia
Conditions: Primary Generalized Epilepsy
Medtronic Deep Brain Stimulation (DBS) Therapy for Epilepsy Post-Approval Study (EPAS)
Recruiting
The purpose of this post-approval study is to further evaluate the long-term safety and effectiveness of Medtronic DBS therapy for epilepsy on seizure reduction in newly implanted participants through 3 years of follow-up.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/31/2024
Locations: Emory University Hospital, Atlanta, Georgia
Conditions: Epilepsy
Safety and Efficacy Study of Cenobamate in Pediatric Subjects 2-17 Years of Age With Partial-onset (Focal) Seizures
Recruiting
Primary objective: To evaluate the safety and tolerability of cenobamate in pediatric subjects 2-17 years of age with partial-onset (focal) seizures
Gender:
All
Ages:
Between 2 years and 18 years
Trial Updated:
01/30/2024
Locations: Augusta University Medical Center, Augusta, Georgia +2 locations
Conditions: Partial Epilepsy
A Study to Evaluate the Efficacy, Safety, and Tolerability of Brivaracetam as Monotherapy in Patients 2 to 25 Years of Age With Childhood Absence Epilepsy or Juvenile Absence Epilepsy
Recruiting
The purpose of the study is to test the efficacy, safety and tolerability of brivaracetam monotherapy in study participants 2 to 25 years of age inclusive with childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE).
Gender:
All
Ages:
Between 2 years and 25 years
Trial Updated:
01/18/2024
Locations: N01269 110, Augusta, Georgia
Conditions: Childhood Absence Epilepsy, Juvenile Absence Epilepsy
A Pragmatic Trial of HOBSCOTCH in Georgia
Recruiting
This study is being done to answer the question: Will a home-based self-management program, HOBSCOTCH, be effective in improving quality of life and perceived difficulties in cognitive abilities by teaching problem-solving strategies? The research team is also looking at a new mobile application that was developed to go with the program, and looking at extra booster sessions to improve long-term outcomes. In order to learn about the effectiveness of the program, half of the people in this study... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/21/2023
Locations: Emory Brain Health Center, Atlanta, Georgia
Conditions: Epilepsy
Electrophysiological Biomarkers in MTLE Patients.
Recruiting
The investigators plan to enroll individuals with medical temporal lobe epilepsy who are undergoing surgical workup with clinically implanted intracranial electrodes. The study intends to administer computerized memory tasks and stimulation during the intracranial Electroencephalography (EEG) monitoring period.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/15/2023
Locations: Epilepsy monitoring unit (EMU) at Emory University Hospital, Atlanta, Georgia
Conditions: Mesial Temporal Lobe Epilepsy