There are currently 16 clinical trials in Champaign, Illinois looking for participants to engage in research studies. Trials are conducted at various facilities, including Women's Health Practice, Christie Clinic, Christie Clinic, LLC and University of Illinois at Urbana-Champaign. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
TIDE Project: Biomarker Discovery for Chronic Tinnitus Diagnosis
Recruiting
Research in clinical neuroscience is founded on the conviction that a better understanding of tinnitus related changes of brain function will improve our ability to diagnose and treat tinnitus. Although considerable advances have been made in understanding the mechanisms of tinnitus, the clinical management of tinnitus remains largely based on a 'trial and error' approach. The identification and validation of a biomarker for tinnitus is thought to be the crucial step in the development of a pers... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
01/28/2025
Locations: University of Illinois, Champaign, Illinois
Conditions: Tinnitus
Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations
Recruiting
The purpose of this Phase III study is to evaluate the efficacy and safety of tozorakimab administered subcutaneously (SC) in adult participants with symptomatic COPD with a history of ≥ 2 moderate or ≥ 1 severe exacerbations of COPD in the 12 months prior to enrolment. Participants should be receiving optimised treatment with inhaled maintenance therapy (ICS/LABA/LAMA triple therapy, or dual therapy if triple is not considered appropriate) throughout at least the last 3 months prior to enrolmen... Read More
Gender:
ALL
Ages:
Between 40 years and 130 years
Trial Updated:
01/20/2025
Locations: Research Site, Champaign, Illinois
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Effects of AZD5004 in Adults Who Are Living With Obesity or Overweight With at Least 1 Weight-related Comorbidity
Recruiting
A Phase IIb, global, randomized, parallel-group, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of AZD5004 compared with placebo, given once daily as an oral tablet(s) for 36 weeks, in male and female participants at least 18 years of age who are living with obesity (body mass index \[BMI\] ≥ 30 kg/m2), or overweight (BMI ≥ 27 kg/m2) who have at least 1 weight-related comorbidity
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/17/2025
Locations: Research Site, Champaign, Illinois
Conditions: Obesity or Overweight
A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.
Recruiting
The purpose of this study is to measure the efficacy and safety of baxdrostat/dapagliflozin in participants ≥ 18 years of age with CKD and HTN. This study consists of a screening, a 4-week dapagliflozin run-in period for participants naïve to SGLT2i at baseline; a 24-month double-blind period in which participants will receive either baxdrostat/dapagliflozin or dapagliflozin; and a 6-week open-label period in which all participants will discontinue baxdrostat/placebo and receive dapagliflozin al... Read More
Gender:
ALL
Ages:
Between 18 years and 130 years
Trial Updated:
01/08/2025
Locations: Research Site, Champaign, Illinois
Conditions: Chronic Kidney Disease and Hypertension
MILD® Percutaneous Image-Guided Lumbar Decompression: a Medicare Claims Study
Recruiting
This prospective longitudinal study will compare incidence rates of Medicare beneficiary surgical and minimally invasive intervention post index procedure, as well as harms associated with the MILD procedure, at 24 months post-treatment with MILD, tested against a control group of similar patients that have had a comparable procedure. This study will start with patients treated with a study procedure having an index date on or after January 1, 2017, and enrollment will continue until stopped by... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/06/2024
Locations: Carle Champaign Surgicenter, Champaign, Illinois
Conditions: Lumbar Spinal Stenosis
Dose Ranging Study of Lunsekimig Compared With Placebo-control in Adult Participants With Moderate-to-severe Asthma
Recruiting
This is a Phase 2b, global, multicenter, randomized, double-blind, placebo-controlled, parallel group, dose ranging study to assess the efficacy, safety, and tolerability of add-on therapy with SC lunsekimig in adult participants aged 18 to 80 years, (inclusive) with moderate-to-severe asthma.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
12/05/2024
Locations: PMG Research of Christie Clinic- Site Number : 8400066, Champaign, Illinois
Conditions: Asthma
Alcohol and the Social Brain: an Alcohol-Administration Hyperscanning Study
Recruiting
In this study, the investigators aim to capture inter- and intra-brain mechanisms underlying alcohol reward in novel social context.
Gender:
ALL
Ages:
Between 21 years and 30 years
Trial Updated:
11/11/2024
Locations: University of Illinois at Urbana-Champaign, Champaign, Illinois
Conditions: Alcohol Drinking, Alcohol Use Disorder, Alcohol Intoxication, Alcohol; Harmful Use, Alcoholism, Binge Drinking
Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms
Recruiting
The study will employ a combined laboratory-ambulatory design. Participants will engage in ambulatory assessment over the course of 14 days, wearing biosensors assessing transdermal alcohol concentration (TAC) and providing breathalyzer readings in real-world contexts. Also during this period, participants will attend three laboratory alcohol-administration sessions scheduled at one-week intervals, with alcohol dose and rate of consumption manipulated within and between participants, respectivel... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
11/08/2024
Locations: University of Illinois at Urbana-Champaign, Champaign, Illinois
Conditions: Alcohol Drinking, Alcohol Intoxication
An Individualized-health eLibrary App for People With Multiple Sclerosis
Recruiting
The purpose of this study is to assess the effectiveness after using a new individualized-health e-library app named SavvyHealth among people with multiple sclerosis.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/08/2024
Locations: University of Illinois Urbana-Champaign, Champaign, Illinois
Conditions: Multiple Sclerosis
A Health Action Process Approach Online Intervention for People With Multiple Sclerosis
Recruiting
The purpose of this study is to implement the person-centered internet-based Health Action Process Approach to promoting physical activity in people with Multiple Sclerosis (i.e., eHAPA-MS online intervention) and assess the intervention's effectiveness and adherence.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/08/2024
Locations: University of Illinois Urbana-Champaign, Champaign, Illinois
Conditions: Multiple Sclerosis
Improving Hypertension Medication Adherence for Older Adults
Recruiting
This randomized controlled trial will assess the efficacy and scalability of a blood pressure technology system intervention. The investigators will enroll 224 older adults with hypertension to identify those who are nonadherent for one hypertension medication. The participants will be randomized to one of two groups (112 per group) to use the blood pressure system for 6-months. Both groups receive information about high blood pressure and medications. One group will also receive strategies that... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
05/03/2024
Locations: University of Illinois Urbana-Champaign, Champaign, Illinois
Conditions: Aging, Medication Adherence, Hypertension
bpMedManage: Digital Technology to Support Adherence to Hypertension Medications
Recruiting
The purpose of the bpMedManage study is to rigorously test the efficacy of a smartphone technology to help improve high blood pressure medication adherence among older adults with mild cognitive impairment (MCI) in a 16-week randomized controlled trial. A total of 100 older adults will be recruited. There will be two treatment arms, bpMedManage-S and bpMedManage-P with 50 participants in each arm. Participants randomized into the bpMEDManage-S intervention arm will use a smartphone application w... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
03/28/2024
Locations: University of Illinois, Urbana-Champaign, Champaign, Illinois
Conditions: Aging, Mild Cognitive Impairment, Hypertension