There are currently 16 clinical trials in Champaign, Illinois looking for participants to engage in research studies. Trials are conducted at various facilities, including Women's Health Practice, Christie Clinic and Christie Clinic, LLC. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Study to Investigate Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin in Participants With Chronic Kidney Disease and High Proteinuria (ZENITH High Proteinuria)
NCT06087835
Recruiting
This is a Phase III, randomised, multicentre, double-blinded study to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney disease (CKD) and high proteinuria.
Gender:
All
Ages:
Between 18 years and 95 years
Trial Updated:
06/19/2024
Locations: Research Site, Champaign, Illinois
Conditions: Chronic Kidney Disease With High Proteinuria
Register for Updates
Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (KALOS)
NCT04609878
Recruiting
This is a variable length study to evaluate the efficacy and safety of budesonide/glycopyrronium/formoterol inhaler in adults and adolescents with severe asthma inadequately controlled with standard of care
Gender:
All
Ages:
Between 12 years and 80 years
Trial Updated:
06/13/2024
Locations: Research Site, Champaign, Illinois
Conditions: Asthma
Register for Updates
Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations
NCT06040086
Recruiting
The purpose of this Phase III study is to evaluate the efficacy and safety of tozorakimab administered subcutaneously (SC) in adult participants with symptomatic COPD with a history of ≥ 2 moderate or ≥ 1 severe exacerbations of COPD in the 12 months prior to enrolment. Participants should be receiving optimised treatment with inhaled maintenance therapy (ICS/LABA/LAMA triple therapy, or dual therapy if triple is not considered appropriate) throughout at least the last 3 months prior to enrolmen... Read More
Gender:
All
Ages:
Between 40 years and 130 years
Trial Updated:
06/03/2024
Locations: Research Site, Champaign, Illinois
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Register for Updates
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR
NCT03142152
Recruiting
The objective of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart failure with functional regurgitation (FMR).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/24/2024
Locations: Carle Foundation Hospital, Champaign, Illinois
Conditions: Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases, Cardiovascular Diseases, Heart Valve Diseases
Register for Updates
A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.
NCT06268873
Recruiting
The purpose of this study is to measure the efficacy and safety of baxdrostat/dapagliflozin in participants ≥ 18 years of age with CKD and HTN. This study consists of a screening, a 4-week dapagliflozin run-in period for participants naïve to SGLT2i at baseline; a 24-month double-blind period in which participants will receive either baxdrostat/dapagliflozin or dapagliflozin; and a 6-week open-label period in which all participants will discontinue baxdrostat/placebo and receive dapagliflozin al... Read More
Gender:
All
Ages:
Between 18 years and 130 years
Trial Updated:
05/22/2024
Locations: Research Site, Champaign, Illinois
Conditions: Chronic Kidney Disease and Hypertension
Register for Updates
An Individualized-health eLibrary App for People With Multiple Sclerosis
NCT05124600
Recruiting
The purpose of this study is to assess the effectiveness after using a new individualized-health e-library app named SavvyHealth among people with multiple sclerosis.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/08/2024
Locations: University of Illinois Urbana-Champaign, Champaign, Illinois
Conditions: Multiple Sclerosis
Register for Updates
A Health Action Process Approach Online Intervention for People With Multiple Sclerosis
NCT05124522
Recruiting
The purpose of this study is to implement the person-centered internet-based Health Action Process Approach to promoting physical activity in people with Multiple Sclerosis (i.e., eHAPA-MS online intervention) and assess the intervention's effectiveness and adherence.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/08/2024
Locations: University of Illinois Urbana-Champaign, Champaign, Illinois
Conditions: Multiple Sclerosis
Register for Updates
Improving Hypertension Medication Adherence for Older Adults
NCT05610059
Recruiting
This randomized controlled trial will assess the efficacy and scalability of a blood pressure technology system intervention. The investigators will enroll 224 older adults with hypertension to identify those who are nonadherent for one hypertension medication. The participants will be randomized to one of two groups (112 per group) to use the blood pressure system for 6-months. Both groups receive information about high blood pressure and medications. One group will also receive strategies that... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
05/03/2024
Locations: University of Illinois Urbana-Champaign, Champaign, Illinois
Conditions: Aging, Medication Adherence, Hypertension
Register for Updates
Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms
NCT05692830
Recruiting
The study will employ a combined laboratory-ambulatory design. Participants will engage in ambulatory assessment over the course of 14 days, wearing biosensors assessing transdermal alcohol concentration (TAC) and providing breathalyzer readings in real-world contexts. Also during this period, participants will attend three laboratory alcohol-administration sessions scheduled at one-week intervals, with alcohol dose and rate of consumption manipulated within and between participants, respectivel... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
04/27/2024
Locations: University of Illinois at Urbana-Champaign, Champaign, Illinois
Conditions: Alcohol Drinking, Alcohol Intoxication
Register for Updates
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
NCT03072927
Recruiting
This prospective longitudinal study will compare incidence rates of Medicare beneficiary surgical and minimally invasive intervention post index procedure, as well as harms associated with the MILD procedure, at 24 months post-treatment with MILD, tested against a control group of similar patients that have had a comparable procedure. This study will start with patients treated with a study procedure having an index date on or after January 1, 2017, and enrollment will continue until stopped by... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: Carle Champaign Surgicenter, Champaign, Illinois
Conditions: Lumbar Spinal Stenosis
Register for Updates
bpMedManage: Digital Technology to Support Adherence to Hypertension Medications
NCT06307574
Recruiting
The purpose of the bpMedManage study is to rigorously test the efficacy of a smartphone technology to help improve high blood pressure medication adherence among older adults with mild cognitive impairment (MCI) in a 16-week randomized controlled trial. A total of 100 older adults will be recruited. There will be two treatment arms, bpMedManage-S and bpMedManage-P with 50 participants in each arm. Participants randomized into the bpMEDManage-S intervention arm will use a smartphone application w... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
03/28/2024
Locations: University of Illinois, Urbana-Champaign, Champaign, Illinois
Conditions: Aging, Mild Cognitive Impairment, Hypertension
Register for Updates
The Effect of the Inclusion of Soybean Flour on Glycemic Responses
NCT06280625
Recruiting
Foods that release glucose rapidly, leading to spikes in blood sugar and insulin (known as high glycemic index foods), generate lower satiety responses than foods with low glycemic index. High glycemic index foods are also linked to an increased risk of developing diabetes. The partial replacement of carbohydrates in rich staple foods with soy flour has the potential to reduce glycemic response and improve satiety. In many regions of Latin America, as well as in the Middle East and North Africa... Read More
Gender:
All
Ages:
Between 21 years and 45 years
Trial Updated:
02/20/2024
Locations: University of Illinois at Urbana Champaign, Champaign, Illinois
Conditions: Overweight and Obesity
Register for Updates