There are currently 62 clinical trials in Carmel, Indiana looking for participants to engage in research studies. Trials are conducted at various facilities, including IU Health North Hospital, Indiana Spine Group, Shideler Clinical Research Center and Laser &Skin Surgery Center of Indiana. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Prospective SPINE Registry
NCT04176562
Recruiting
This study is a prospective, multi-center, open label registry designed to collect real-world data on performance and safety data on RTI's spine products.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/08/2024
Locations: Indiana Spine Group, Carmel, Indiana
Conditions: Sacroiliac; Fusion, Sacroiliac, Joint Diseases, Musculoskeletal Diseases, Spinal Disease, Spinal Stenosis, Spinal Instability, Fusion of Joint, Fusion of Spine, Spinal Fusion, Spine
Register for Updates
Biomarker of Diabetic Retinopathy
NCT05079399
Recruiting
Diabetic retinopathy (DR) is a complication of diabetes in which blood vessels supplying blood to the back of the eye (retina) are dysfunctional. This can lead to an improper supply of oxygen and nutrients to the retinal tissue, or it may trigger the formation of new blood vessels in response to the oxygen/nutrient deficiency. Ultimately affecting the normal vision. There is no known marker that will provide information on the health status of retinal blood vessels. Using highly specialized cell... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Spring Mill Clinic, Carmel, Indiana
Conditions: Diabetic Retinopathy
Register for Updates
Molecular Mechanisms Associated With Breast Implant Complications
NCT05736354
Recruiting
Bacterial biofilms cause implant failures, chronic inflammation, and immune polarization. The study investigates the possible role of bacterial biofilm as a factor in the etiology of Breast Implant Illness. Three patient cohorts will be studied (A) Subjects with breast implant with BII manifestations (B) Subjects with breast implants without BII manifestations (C) Subjects without breast implants who underwent breast surgery procedure. Blood, surgically discarded tissue, implants, and associated... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: IU Health North Hospital, Carmel, Indiana +1 locations
Conditions: Breast Implant; Complications, Infection or Inflammation
Register for Updates
Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Neurotrophic Keratitis Subjects
NCT04909450
Recruiting
This study will enroll subjects with stage 2 or 3 neurotrophic keratitis. Subjects will be randomized in a 1:1 ratio to the CSB-001 investigational treatment arm or vehicle control arm. All subjects will dose with the randomized treatment four times daily for 8 weeks (controlled treatment phase). During the controlled treatment phase, subjects will return to the clinic weekly from Day 0 to Week 8, and again at Week 10. Subjects randomized to the vehicle arm who are not healed will have the oppor... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: Midwest Cornea Associates, LLC, Carmel, Indiana
Conditions: Neurotrophic Keratitis
Register for Updates
4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration
NCT05197270
Recruiting
Phase 1/2 dose-escalation and randomized, controlled, masked expansion trial in adults with wet AMD undergoing active anti-VEGF treatment
Gender:
All
Ages:
50 years and above
Trial Updated:
02/15/2024
Locations: Retina Partners Midwest, Carmel, Indiana
Conditions: Neovascular (Wet) Age-Related Macular Degeneration
Register for Updates
Safety and Effectiveness of the Genio® bilAteral Stimulation for Treatment of Complete Concentric CollapsE and OSA.
NCT05592002
Recruiting
The solution offered by the Genio System to treat OSA patients with CCC using bilateral HGNS has a favorable risk-benefit ratio, as demonstrated by evidence from 2 studies.
Gender:
All
Ages:
Between 22 years and 75 years
Trial Updated:
02/12/2024
Locations: Center for ENT and Allergy, PC Ascension Medical Group, Carmel, Indiana
Conditions: Sleep Apnea, Obstructive
Register for Updates
A Study of Infuse® Bone Graft With Mastergraft® Strip and Posterior Fixation for Posterolateral Fusion (PLF) Treatment of Multi-Level Degenerative Lumbosacral Spinal Conditions
NCT03118505
Recruiting
The purpose of this study is to obtain safety and effectiveness data on the investigational device for multi-level PLF procedures and determine the most appropriate rhBMP-2 dose for use in this indication. The study information may be used for a potential pivotal study design.
Gender:
All
Ages:
21 years and above
Trial Updated:
01/24/2024
Locations: Indiana Spine Group, Carmel, Indiana
Conditions: Multi-Level Degenerative Lumbosacral Spinal Conditions
Register for Updates
Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer
NCT05646316
Recruiting
This phase III trial compares the effect of sentinel lymph node mapping to standard lymph node dissection in reducing the risk of swelling in the legs (lymphedema) in patients undergoing a hysterectomy for stage I endometrial cancer. Standard lymph node dissection removes lymph nodes around the uterus during a hysterectomy to look for spread of cancer from the uterus to nearby lymph nodes. Sentinel lymph node mapping uses a special dye and camera to look for cancer that may have spread to nearby... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
01/16/2024
Locations: IU Health North Hospital, Carmel, Indiana
Conditions: Stage I Uterine Corpus Cancer AJCC v8
Register for Updates
The Synergy Disc for the Treatment of 2 Level Cervical Degenerative Disc Disease Compared With Cervical Fusion Surgery
NCT05740176
Recruiting
A multicenter, prospective, non-randomized, historically controlled study. To demonstrate the Synergy Disc is at least as safe and effective as conventional anterior cervical discectomy and fusion (ACDF) to treat cervical degenerative disc disease (DDD) in subjects who are symptomatic at two levels from C3 to C7 are and are unresponsive to conservative management. Patients will be evaluated preoperatively, at the time of surgery, and at 6 weeks, and 3, 6, 12, and 24 months after surgery. Follow-... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/15/2024
Locations: Indiana Spine Group, Carmel, Indiana
Conditions: Cervical Degenerative Disc Disease
Register for Updates
Phase 2b Study of ALTO-100 in MDD
NCT05712187
Recruiting
The purpose of this study is to determine efficacy differences between ALTO-100 and placebo, used either as monotherapy or adjunctively to an antidepressant, related to patient characteristics.
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
01/10/2024
Locations: Site 137, Carmel, Indiana
Conditions: Major Depressive Disorder
Register for Updates
REal-World Analyses of Stroke - Thrombus Occlusion REtrieval
NCT04451525
Recruiting
To collect real-world evidence allowing assessment of functional, imaging, and safety outcomes of MicroVention market-released acute ischemic stroke devices when used at the direction of the treating physician.
Gender:
All
Ages:
All
Trial Updated:
12/15/2023
Locations: Goodman Campbell Brain and Spine, Carmel, Indiana
Conditions: Acute Ischemic Stroke, Stroke, Ischemic, Vessel Occlusion
Register for Updates
Exercise Intervention in Adolescent and Young Adult Cancer Survivors
NCT04265638
Recruiting
Adolescent and young adult (AYA) survivors of cancer face a future of persistent medical issues across a wide spectrum of diseases One study examining health data from this cohort (ages 15-29) reported significantly higher rates of smoking, obesity, cardiovascular disease, hypertension, asthma, and poorer mental health among the cancer survivors when compared to healthy controls. Prescribed exercise has broad and far-reaching beneficial physiological effects that cut across multiple body systems... Read More
Gender:
All
Ages:
Between 15 years and 39 years
Trial Updated:
11/27/2023
Locations: IU Health North Hospital, Carmel, Indiana
Conditions: Long-term Effects Secondary to Cancer Therapy in Adults, Pediatric Cancer
Register for Updates