The state of Indiana currently has 21 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including Indianapolis, South Bend, Fort Wayne and Evansville.
QST Study: Predicting Treatment Response in Chronic Pancreatitis Using Quantitative Sensory Testing
NCT03434392
Recruiting
Quantitative Sensory Testing (QST) is a novel investigative technique used in other pain conditions to evaluate patterns of chronic pain, and in this study will be used to elucidate pain patterns in patients with Chronic Pancreatitis (CP). QST uses a specific series of standardized stimulations to map the pain system. QST has the potential to change and improve the treatment paradigm for patients with CP and may eventually be able to predict response to invasive CP therapies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/07/2025
Locations: Indiana University Medical Center, Indianapolis, Indiana
Conditions: Chronic Pancreatitis, Chronic Pain
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Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis
NCT04996628
Recruiting
Abdominal pain in chronic pancreatitis (CP) affects up to 90% of patients during the course of their disease, and response to currently available therapies is suboptimal and unpredictable. The proposed clinical trial will evaluate the predictive capability of Pancreatic Quantitative Sensory Testing (P-QST) - a novel assessment of neurosensory phenotyping- for improvement in pain in patients with CP who are undergoing medically-indicated invasive treatment with endoscopic therapy or surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/07/2025
Locations: Indiana University Medical Center, Indianapolis, Indiana
Conditions: Chronic Pancreatitis, Chronic Pain
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Pre-Rehabilitation for Female Patients Undergoing Pelvic Radiotherapy
NCT06059586
Recruiting
The purpose of this study is to examine the feasibility of adding pre-rehabilitation pelvic health physical therapy to standard of care radiation therapy treatment plan for female patients who have been diagnosed with cervical, vaginal, vulvar, uterine, or anal cancer and are a candidate for curative pelvic radiation with external beam. Participants will receive education on using a vaginal dilator for use during treatment and complete questionnaires looking at pain and sexual function.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/22/2024
Locations: IU Health Schwarz Cancer Center, Carmel, Indiana
Conditions: Dyspareunia, Pelvic Pain, Sexual Dysfunction, Radiation Toxicity
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Options for Pain Management Using Nonpharmacological Strategies
NCT05563792
Recruiting
The purpose of this study is to help Veterans learn about different ways they can manage chronic pain that do not involve medications. Veterans will work with a coach to explore the Veterans' values and goals and how different non-medication approaches may fit into these values and goals.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/02/2024
Locations: Richard L. Roudebush VA Medical Center, Indianapolis, IN, Indianapolis, Indiana
Conditions: Pain
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VIA Disc NP Registry 3.0
NCT06345690
Recruiting
Registry is to observe and trend patterns of care and outcomes for patients treated with VIA Disc NP.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/16/2024
Locations: The Orthopedic Research Foundation, Inc., Fishers, Indiana
Conditions: Discogenic Pain, Back Pain, Back Pain, Low
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Long-Term Real-World Outcomes Study on Patients Implanted With a Neurostimulator
NCT03876054
Recruiting
The REALITY study is a prospective, post-market, non-randomized, multi-center, single-arm, open-label study intended to collect short- and long-term safety and effectiveness data on various populations implanted with Abbott's neurostimulation systems.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: Goodman Campbell Brain and Spine, Indianapolis, Indiana
Conditions: Chronic Pain
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The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture
NCT06420141
Recruiting
This application addresses the Peer Reviewed Medical Research Program Investigator-Initiated Research Award FY21 W81XWH-22-CPMRP-IIRA area of Chronic Pain Management Research Program- The investigators will utilize subjects who have sustained ankle fractures and may develop chronic pain following bone union. No attempt will be made to affect the experimental outcome in the subjects. This study will adhere to a core set of standards for rigorous study design and reporting to maximize the reproduc... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
05/16/2024
Locations: Indiana University School of Medicine, Indianapolis, Indiana
Conditions: Neuropathic Pain
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Surgical Myomectomy Followed by Oral Myfembree Versus Standard of Care Trial (SOUL)
NCT05538689
Recruiting
In this project, the proposition is that the use of daily dosed Myfembree ( a combination of relugolix with estradiol and norethindrone acetate), FDA-approved medication to treat heavy menses fibroid-related symptoms, has the potential to delay the recurrence of fibroid symptoms, prolong the improved quality of life and delay the need for re-intervention after uterine sparing surgery versus the routine standard of care.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of Chicago Schererville, Schererville, Indiana
Conditions: Metrorrhagia, Pelvic Pain, Menorrhagia, Leiomyoma
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SynerFuse Spinal Fusion and Neuromodulation Proof of Concept Study
NCT04054401
Recruiting
The purpose of the study is to evaluate the safety and tolerability of DRG stimulation when placing a neurostimulator during the same procedure as implantation of spinal fixation with or without interbody cage systems in patients with chronic back and/or leg pain requiring single level spinal fusion.
Gender:
ALL
Ages:
Between 21 years and 80 years
Trial Updated:
11/21/2023
Locations: South Bend Orthopaedics, Mishawaka, Indiana
Conditions: Spinal Fusion, Radiculopathy Lumbar, Chronic Pain
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