There are currently 113 clinical trials in Fort Wayne, Indiana looking for participants to engage in research studies. Trials are conducted at various facilities, including Fort Wayne Medical Oncology and Hematology, Fort Wayne Medical Oncology and Hematology Inc-Parkview, Parkview Hospital Randallia and Parkview Regional Medical Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer
NCT04729114
Recruiting
Medicines that reduce the amount of testosterone in the body are commonly used to treat prostate cancer. PRL-02 depot is a potential treatment for men with advanced prostate cancer. It is given by an injection into the muscle. Men with advanced prostate cancer can take part in this study. Their cancer has come back after previous cancer treatment, or the previous cancer treatment they had didn't work. The main aims of the study are: * to check the safety of PRL-02 depot given with and without... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
03/18/2025
Locations: Fort Wayne Medical Oncology and Hematology, Inc., Fort Wayne, Indiana
Conditions: Prostate Cancer, Metastatic Castration Resistant Prostate Cancer, Metastatic Castration-sensitive Prostate Cancer
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Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
NCT03851445
Recruiting
This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid Master Protocol (Lung-MAP). The type of cancer trait (biomarker) will determine to which sub-study, within this protocol, a participant will be assigned to compare new targeted cancer therapy, designed to block the growth and spread of cancer, or combinations to standard of... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/12/2025
Locations: Parkview Regional Medical Center, Fort Wayne, Indiana
Conditions: Previously Treated Non-Small Cell Lung Cancer
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Amplatzer Amulet LAAO Vs. NOAC
NCT04226547
Recruiting
The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy. The clinical investigation is a prospective, randomized, multicenter active control worldwide trial. Subjects will be randomized in a 1:1 ratio between the Amulet LAA occlusion device ("Device Group") and a commercially available NOAC medication ("Cont... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: Lutheran Hospital of Indiana, Fort Wayne, Indiana
Conditions: Atrial Fibrillation, Stroke, Bleeding
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BostonGene and Exigent Genomic INsight Study
NCT06272864
Recruiting
The BEGIN Study by BostonGene and Exigent Genomic INsight evaluates the efficacy of comprehensive molecular testing in advanced cancer patients. Using the BostonGene Tumor Portrait test, the study aims to identify actionable findings, assess feasibility, and determine patient enrollment in clinical trials. Four cohorts of 100 patients each will be studied over two years, focusing on treatment decisions and patient outcomes. This study seeks to demonstrate the clinical utility of genomic testing... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/14/2025
Locations: Fort Wayne Medical Oncology and Hematology, Fort Wayne, Indiana
Conditions: Breast Cancer, Non-small Cell Lung Cancer, Melanoma, Sarcoma
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Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
NCT04045665
Recruiting
The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying POAF event, who decline randomization, will be offered the option of enrollment in a parallel registry that captures their ba... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/05/2025
Locations: Lutheran Medical Center, Fort Wayne, Indiana
Conditions: Atrial Fibrillation, Stroke, Bleeding
Register for Updates
Evaluation of the Clinical Utility of Endoscopic Closure Using a Dual Action Tissue (DAT) Clip
NCT05852457
Recruiting
This study is designed as a multicenter prospective data recording study to document the performance of the DAT clip as part of standard medical care of patients. No experimental interventions will be performed.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/14/2025
Locations: Parkview Health, Fort Wayne, Indiana
Conditions: GI Bleeding, Perforation Colon, Perforation Bowel, Perforation Duodenal, Perforated Bowel, Fistula
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Families of Youth with Developmental Disabilities: a Theory-Based Intervention
NCT03495440
Recruiting
This study is designed to evaluate a preventive intervention program designed to support families (parents and typically developing adolescent siblings) that include a child with an intellectual and/or developmental disability. Participant families will be randomly assigned to either the treatment condition, in which they will receive psychoeducation and communication coaching over a four-week period, or the control condition, in which they will receive self-study materials. All subjects will pa... Read More
Gender:
ALL
Ages:
All
Trial Updated:
11/13/2024
Locations: Wm. J. Shaw Center for Children and Families, Fort Wayne, Indiana
Conditions: Family Conflict, Marital Conflict, Communication
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The Happy Families Project: Testing the Effectiveness of a Conflict Resolution Program for Families
NCT04980794
Recruiting
This study is designed to test the effectiveness of a psychoeducation-based program to address communication and conflict resolution in families, thereby supporting mental health in children and their caregivers.
Gender:
ALL
Ages:
4 years and above
Trial Updated:
11/13/2024
Locations: Fort Wayne Center for Children and Families, Fort Wayne, Indiana
Conditions: Mental Health, Conflict
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RRx-001 for Reducing Oral Mucositis in Patients Receiving Chemotherapy and Radiation for Head and Neck Cancer
NCT05966194
Recruiting
The purpose of this study is to determine if RRx-001, which is added on to the cisplatin and radiation treatment, reduces the incidence of severe oral mucositis in patients with head and neck cancers. All patients in this study will receive 7 weeks of standard of care radiation therapy given with the chemotherapy agent, cisplatin. Patients will receive RRx-001 or placebo before start of standard of care treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: Parkview Cancer Institute, Fort Wayne, Indiana
Conditions: Oral Mucositis
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Patient Specific Talus Spacer Post Approval Study
NCT05364606
Recruiting
Humanitarian Device Exemption Approved Patient Specific Talus Spacer Post Approval Study.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
11/05/2024
Locations: Fort Wayne Orthopedics, Fort Wayne, Indiana
Conditions: Avascular Necrosis of the Talus
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FID-007 and Cetuximab in Treating Patients With Advanced Head and Neck Squamous Cell Carcinoma
NCT06332092
Recruiting
The goal of this FID-007 Clinical Trial is to compare the efficacy of different dosing regimens of FID-007 in combination with Cetuximab in patients with recurrent or metastatic Head and Neck Squamous Cell Carcinoma (HNSCC). The main questions it aims to answer are: to evaluate the efficacy, and to characterize the safety and tolerability. Eligible participants will be enrolled and randomized to 1 of 2 arms of FID-007 with fixed-dose Cetuximab in each 28-day cycle.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/05/2024
Locations: Fort Wayne Medical Oncology and Hematology, Fort Wayne, Indiana
Conditions: Head and Neck Squamous Cell Carcinoma
Register for Updates
First in Human Study of TORL-3-600 in Participants With Advanced Cancer
NCT05948826
Recruiting
This first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-3-600 in patients with advanced cancer
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/18/2024
Locations: Fort Wayne Medical Oncology and Hematology Inc., Fort Wayne, Indiana
Conditions: Advanced Solid Tumor, Colorectal Cancer
Register for Updates