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Asthma Clinical Trials in Indianapolis, IN
A listing of 12 Asthma clinical trials in Indianapolis, IN actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 12
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The city of Indianapolis, Indiana, currently has 12 active clinical trials seeking participants for Asthma research studies.
Featured Trial
A Study on the Efficacy, Safety, and Tolerability of an Investigational Drug in Participants with Severe Eosinophilic Asthma
Recruiting
The primary aim of this clinical trial is to study the potential effectiveness of an investigational drug in treating severe eosinophilic asthma, characterized by persistent symptoms and frequent flare-ups despite regular asthma medication. Secondary goals of this study include evaluating the safety and tolerability aspects of the investigational drug. To maintain objectivity, participants are randomly assigned into groups, receiving either the actual drug or a placebo. The outcome of this research will be instrumental in determining if the investigational drug stands as a possible treatment for those grappling with severe eosinophilic asthma. If you are interested in applying for this study, initiating contact will lead to direct engagement from the research site. They will provide more information on the study and answer any questions related to participation requirements, the potential risks and benefits, and any compensation on offer.
Conditions:
Asthma
All Conditions
Featured Trial
Studying an Investigational Medication in Adults with Eczema
Recruiting
The main objectives of this study are to evaluate the safety and effectiveness of an investigational medication in adults with moderate to severe atopic dermatitis, commonly known as eczema. The study aims to understand how different dosages of the investigational medication affect eczema flare ups. Participants will be randomly assigned to receive various dosages of the investigational medication or a placebo. Should you express interest, you will be contacted directly by the research site, who will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
All Conditions
Dermatology
Eczema (Atopic dermatitis)
Featured Trial
High Triglyceride Clinical Research Study
Recruiting
Living with high triglycerides? See if our clinical study is right for you.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Conditions:
High Triglycerides
High Triglyceride Level
Hypertriglyceridemia
Elevated Triglycerides
Triglycerides High
Featured Trial
Lose Weight with GLP-1 Medications
Recruiting
Policy Lab has partnered with CareGLP to offer trusted access to GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®.
GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.
As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.
GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.
As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.
Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Studying an Investigational Virus Vaccine
Recruiting
The main objectives of this study are to assess the safety and effectiveness of an investigational vaccine aimed at preventing norovirus, commonly known as the stomach flu. Participants will be randomly assigned to receive either the investigational vaccine or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Healthy
Interested in vaccine studies
All Conditions
Preventative Trials
Study to Assess the Efficacy and Safety of Atuliflapon in Moderate-to-Severe Uncontrolled Asthma
Recruiting
This is a randomised, placebo-controlled, double-blind study to assess the efficacy and safety of Atuliflapon administered once daily over a 12-week treatment period to adult participants with moderate to severe uncontrolled asthma.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
02/14/2025
Locations: Research Site, Indianapolis, Indiana
Conditions: Asthma
Benralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics
Recruiting
The purpose of the study is to evaluate effect of benralizumab on structural and lung function changes in severe eosinophilic asthmatics.
Changes will be assessed over 48 week treatment period in patients with persistent symptoms despite standard therapy of inhaled corticosteroids (ICS) plus long acting B2-agonist (LABA) with or without additional controller medication.
Patients who complete treatment will enter 4 weeks follow-up period.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
02/12/2025
Locations: Research Site, Indianapolis, Indiana
Conditions: Asthma
Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma
Recruiting
The purpose of this study is to compare the effect of budesonide/albuterol metered-dose inhaler (BDA MDI) with albuterol sulfate metered-dose inhaler (AS MDI), both administered as needed, on the annualized rate of severe asthma exacerbations in adolescents with a documented clinical diagnosis of asthma and at least one severe exacerbation in the prior year.
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
12/19/2024
Locations: Research Site, Indianapolis, Indiana
Conditions: Asthma
Evaluate Pharmacokinetics and Safety of Slow Release DHEA
Recruiting
This is a study to look at pharmacokinetic levels of different doses of slow release DHEA in subjects with asthma.
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
12/05/2024
Locations: Riley Hospital for Children, Indianapolis, Indiana +1 locations
Conditions: Asthma, Genotype
Acoustic Waveform Respiratory Evaluation
Recruiting
The study will evaluate the feasibility of using smartphone speakers and microphones to evaluate the caliber of the airways, detect airway obstruction, aid in airway disease diagnosis, and identify disease exacerbations.
Gender:
ALL
Ages:
Between 8 years and 65 years
Trial Updated:
09/11/2024
Locations: Indiana University, Indianapolis, Indiana
Conditions: Asthma, COPD, Cystic Fibrosis, Ciliary Motility Disorders, Bronchiectasis, Airway Malacia, Healthy Control
Developing a Childhood Asthma Risk Passive Digital Marker
Recruiting
Underdiagnosis and undertreatment is a major problem in childhood asthma management, especially in preschool-aged children. Current prognostic approaches using risk-score based tools have poor-to-modest accuracy, are impractical, and have limited evidence of efficacy in clinical settings and hence are not widely used in practice.
The objective of the study is to determine the usability, acceptability, feasibility, and preliminary efficacy of the childhood asthma passive digital marker (PDM) amo... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/23/2024
Locations: Indiana University, Indianapolis, Indiana
Conditions: Pediatric Asthma
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Recruiting
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK of understudied drugs currently being administered to children per SOC as prescribed by their treating provider.
Gender:
ALL
Ages:
Between 0 years and 20 years
Trial Updated:
06/27/2024
Locations: Riley Hospital for Children at Indiana University, Indianapolis, Indiana
Conditions: Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Hemophilia, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
VCSIP Follow-up Study
Recruiting
The overall aims of this protocol are to determine whether prenatal supplementation with vitamin C to pregnant smokers can improve pulmonary function and decrease wheeze at 5 years of age in their offspring. This is a continuation of the VCSIP trial, to follow the offspring through 5 years of age. The hypothesis for this protocol is an extension of the VCSIP trial that supplemental vitamin C in pregnant smokers can significantly improve their children's PFTs and decrease the incidence of wheeze.
Gender:
All
Ages:
Between 6 months and 4 years
Trial Updated:
04/15/2024
Locations: Indiana University, Indianapolis, Indiana
Vitamin C Supplementation to Pregnant Smokers: Follow-up of 2 Randomized Trials Plus Changes in DNA Methylation
Recruiting
In a randomized clinical trial (RCT) published in JAMA, the investigators have provided evidence that vitamin C supplementation (500 mg daily during pregnancy) ameliorates the effects of maternal smoking during pregnancy on offspring lung function and subsequent incidence of wheeze by 48% through 1 year of age. The investigators are currently completing a second RCT of vitamin C supplementation in pregnant smokers with more robust measures of pulmonary outcomes. The purpose of this ECHO applicat... Read More
Gender:
All
Ages:
Between 6 months and 11 years
Trial Updated:
04/15/2024
Locations: Indiana University, Indianapolis, Indiana
Project 2 Airway Potential Hydrogen (pH) in Asthma
Recruiting
This study is testing a non invasive way to measure airway pH in individuals with Asthma and Cystic Fibrosis using a new inhaled drug. The airway pH will help health care providers in creating tailored treatment plans for individuals suffering from these specific conditions.
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
03/13/2024
Locations: Indiana University School of Medicine, Indianapolis, Indiana
5HTP Regulation Of Asthma In Children
Recruiting
The purpose of this study is to learn more about if taking a supplement called 5-hydroxytryptophan (5HTP) can improve breathing and anxiety symptoms related to asthma. To help learn more subjects will either be assigned to a group that is taking the supplement (5HTP) or a group that is taking a placebo. This will be decided randomly. Later in the study subjects will crossover to the other group.There are 5 study visits over the course of about 12 weeks.
Gender:
All
Ages:
Between 8 years and 18 years
Trial Updated:
02/26/2024
Locations: Indiana University, Indianapolis, Indiana
Conditions: Mild or Moderate Asthma With Allergic Sensitization
Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up
Recruiting
The overall aims of this protocol are to determine whether prenatal supplementation with vitamin C to pregnant smokers can improve pulmonary function at 10 years of age in their offspring. This is an additional continuation of the Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) trial, to follow the offspring through 10 years of age. The hypothesis for this protocol is an extension of the VCSIP trial that supplemental vitamin C in pregnant smokers can signifi... Read More
Gender:
All
Ages:
Between 6 years and 16 years
Trial Updated:
11/17/2023
Locations: Indiana University, Indianapolis, Indiana
1 - 12 of 12