The city of Indianapolis, Indiana, currently has 6 active clinical trials seeking participants for Depression research studies.
Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled study in pediatric patients who are experiencing major depressive episodes (MDEs) associated with a primary diagnosis of bipolar I or bipolar II disorder as confirmed by Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL), according to criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM 5).
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
04/22/2024
Locations: Clinical Site, Indianapolis, Indiana
Conditions: Bipolar Depression
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
Recruiting
Objectives of this study are to determine whether active VNS Therapy treatment is superior to a no stimulation control in producing a reduction in baseline depressive symptom severity, based on multiple depression scale assessment tools at 12 months from randomization.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2024
Locations: Advanced Research Institute, Inc., Indianapolis, Indiana
Conditions: Treatment Resistant Depression
Pilot Testing a Virtual Mindfulness-Based Intervention to Improve Veterans' Health
Recruiting
The purpose of this study is to test a mindfulness-based intervention to reduce depressive symptoms and improve Veterans' community reintegration.
Gender:
All
Ages:
Between 18 years and 44 years
Trial Updated:
12/11/2023
Locations: Richard L. Roudebush VA Medical Center, Indianapolis, IN, Indianapolis, Indiana
Conditions: Depression
POST Facilitation for Community Dwelling Older Adults (POST-RCT)
Recruiting
We propose to study the effects of Physician Orders for Scope of Treatment (POST) Facilitation in a randomized controlled trial in a population of community dwelling older adults who qualify for POLST facilitation, including those with normal cognition and those with Alzheimer's Disease and Related Disorders.
Gender:
All
Ages:
65 years and above
Trial Updated:
11/13/2023
Locations: Eskenazi Health, Indianapolis, Indiana +2 locations
Conditions: Anxiety, Depression, Post Traumatic Stress Disorder, Satisfaction
Digital Single Session Intervention for Youth Mental Health
Recruiting
The aim of this study is to test the effectiveness of a single-session, digital intervention teaching the principle of practicing the opposite, when administered to youths on the waitlist for psychotherapy, with usual waitlist procedures as a control condition.
Gender:
All
Ages:
Between 9 years and 17 years
Trial Updated:
09/21/2023
Locations: Riley Child Psychiatry and Behavioral Sciences Clinic, Indianapolis, Indiana
Conditions: Anxiety, Depression, Conduct Disorder, Stress
Academic-Community EPINET (AC-EPINET)
Recruiting
The investigators propose to examine the effects of CSC services delivered via TH (CSC-TH) versus the standard clinic-based CSC model (CSC-SD) on engagement and outcomes in a 12-month, randomized trial.
Gender:
All
Ages:
Between 16 years and 35 years
Trial Updated:
05/16/2023
Locations: Prevention and Recovery Center for Early Psychosis, Indianapolis, Indiana
Conditions: Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorders, Major Depression With Psychotic Features, Bipolar Disorder With Psychotic Features