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Arthritis Paid Clinical Trials in Iowa
A listing of 10 Arthritis clinical trials in Iowa actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 10 of 10
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Conditions:
Healthy
Healthy Volunteer Study
Featured Trial
Herpes Clinical Trial
Recruiting
Help move the future of herpes simplex virus type 2 (HSV-2) genital herpes forward by participating in the Vantage Trial for an investigational vaccine.
Conditions:
HSV-2 Infection
HSV-2
Herpes
Herpes Simplex
Genital Herpes
Genital Herpes Simplex Type 2
HSV-2 Genital Herpes
HIV-1 and HSV-2 Coinfection
Featured Trial
Fronto-Temporal Dementia Research Study
Recruiting
The aim of this study is to better understand the genetics of FTD, in order to
empower researchers with the data they need to potentially identify treatment
options. Help researchers accelerate their understanding of Frontotemporal
Dementia and get access to free, at-home genetic testing and genetic counseling
before and after your test.
empower researchers with the data they need to potentially identify treatment
options. Help researchers accelerate their understanding of Frontotemporal
Dementia and get access to free, at-home genetic testing and genetic counseling
before and after your test.
Conditions:
Dementia
Frontotemporal Dementia
Alzheimer Dementia
Dementia Alzheimers
Mild Dementia
Dementia
Alzheimer Type
Alzheimer Disease
Alzheimer's Disease
Dementia of Alzheimer Type
Parkinson's Disease
Parkinson Disease
Idiopathic Parkinson's Disease
ALS
Memory Disorders
Memory Impairment
Memory Loss
Age-Related Memory Disorders
Featured Trial
Clinical Research for Alpha-1 Antitrypsin Deficiency–Associated Liver Disease
Recruiting
The Redwood Study is currently enrolling adults 18 to 75 years of age with Alpha-1
Liver Disease. The purpose of the study is to evaluate how safe and effective an
investigational study drug is compared to a placebo (both groups will receive
injections, but the placebo contains no active medication) in the treatment of liver
disease. If you or any of your family members have a confirmed or suspected
diagnosis of Alpha-1 Liver Disease, you may be eligible.
Liver Disease. The purpose of the study is to evaluate how safe and effective an
investigational study drug is compared to a placebo (both groups will receive
injections, but the placebo contains no active medication) in the treatment of liver
disease. If you or any of your family members have a confirmed or suspected
diagnosis of Alpha-1 Liver Disease, you may be eligible.
Conditions:
Crohn's Disease
COPD
Chronic Obstructive Pulmonary Disease (COPD)
Emphysema or COPD
Alpha 1-Antitrypsin Deficiency
AAT Deficiency
AATD
Chronic Obstructive Pulmonary Disease
Emphysema
Pulmonary Emphysema
Bronchiectasis
Panniculitis
Hepatocellular Carcinoma
Cirrhosis
Liver Cirrhosis
Cirrhosis
Liver
Cystic Fibrosis
Idiopathic Pulmonary Fibrosis
Pulmonary Fibrosis
Non-Alcoholic Fatty Liver Disease
Liver Diseases
Liver Disease
Iterative Design of Custom Dynamic Orthoses to Reduce Articular Contact Stress
Recruiting
The proposed study evaluates the effect of carbon fiber brace design on forces across the ankle joint. Research suggests that ankle arthritis develops after ankle fracture, in part, due to elevated forces on the cartilage. It is expected that carbon fiber braces can be designed to reduce forces in the ankle joint and thereby reduce the risk of developing arthritis following traumatic injury. In this study, brace geometry will be varied to determine how these changes influence the forces experien... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
11/06/2023
Locations: University of Iowa, Iowa City, Iowa
Conditions: Ankle Fractures, Post-traumatic Osteoarthritis, Osteoarthritis Ankle
Comparative Effect of Carbon Fiber Orthosis Cuff Design on Preference, Comfort, and Mechanics
Recruiting
Carbon fiber custom dynamic orthoses (CDOs) consist of a proximal cuff that wraps around the leg just below the knee, a posterior carbon fiber strut that stores and returns energy during gait, and a carbon fiber foot plate that supports the foot and allows bending of the posterior strut. The proximal cuff is a primary interface between the patient and the CDO and may influence comfort, preference, limb mechanics and loading, and effective stiffness of the CDO. The important role of the proximal... Read More
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
11/06/2023
Locations: University of Iowa, Iowa City, Iowa
Conditions: Healthy, Lower Limb Injury, Post-Traumatic Osteoarthritis
Microfragmented Adipose Tissue Compared to Corticosteroid Injection for the Treatment of Knee Osteoarthritis
Recruiting
The goal of this clinical trial is to examine the effect of a single autologous, intra-articular injection of MFat versus corticosteroid injection for the treatment of pain and function associated with K/L grade 2/3 knee Osteoarthritis.
Participants will receive an injection of MFat or a corticosteroid.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/02/2023
Locations: University of Iowa Sports Medicine, Iowa City, Iowa
Conditions: Knee Osteoarthritis, Osteo Arthritis Knee
Translating Metabolic Responses to Mechanical Insult Into Early Interventions to Prevent PTOA
Recruiting
This is a small-scale proof-of concept clinical trial of amobarbital as a treatment to prevent post-traumatic osteoarthritis in fractured ankle joints. The study is a double blind, prospective, randomized, placebo-controlled, stepwise trial. Amobarbital will be delivered to ankle joints in solution with hyaluronic acid (HA) as a vehicle. Amobarbital/HA injections (active dose) will be compared to HA alone (placebo dose). Our primary goal is to confirm safety, but we will also assess whether trea... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
09/21/2023
Locations: University of Iowa, Iowa City, Iowa
Conditions: Osteoarthritis, Post-traumatic Osteoarthritis
Biologic Abatement and Capturing Kids' Outcomes and Flare Frequency in Juvenile Spondyloarthritis
Recruiting
This randomized pragmatic trial will generate knowledge about strategies used to de-escalate tumor necrosis factor inhibitor (TNFi) therapy in patients with juvenile spondyloarthritis with sustained inactive disease and are treated at one of the 29 participating pediatric healthcare systems. This open label study will be conducted in the setting of routine clinical care and will compare the risk and timing of flare (Aim 1) and patients' lived experiences (Aim 2) across three arms.
Gender:
All
Ages:
Between 8 years and 21 years
Trial Updated:
08/08/2023
Locations: University of Iowa Stead Family Children's Hospital, Iowa City, Iowa
Conditions: Juvenile Spondyloarthritis
Preventing Extension of Oligoarticular Juvenile Idiopathic Arthritis JIA (Limit-JIA)
Recruiting
This is a research study to test whether a once-weekly injection of abatacept will prevent the progression of Juvenile Idiopathic Arthritis (JIA) to a more severe form. To evaluate the effectiveness of a 24-week course of treatment with abatacept plus usual care versus usual care to prevent polyarthritis (≥5 joints), uveitis, or treatment with other systemic medication within 18 months of randomization in children with recent-onset limited JIA.
Gender:
All
Ages:
Between 2 years and 16 years
Trial Updated:
08/01/2023
Locations: University of Iowa Hospitals of Clinics, Iowa City, Iowa
Conditions: Juvenile Idiopathic Arthritis
Pregabalin for Central Sensitization in TKA
Recruiting
The study purpose is to determine if giving pregabalin before and after total knee arthroplasty (TKA) can improve pain and meaningful function after surgery in patients that have central sensitization (CS).
Participants will be identified who are indicated for TKA. Interested patients will complete a standard Knee Injury and Osteoarthritis Outcomes Score (KOOS), asked their pain score (on a scale of 0 to 10), and complete the Central Sensitization Inventory (CSI). If they meet inclusion criteri... Read More
Gender:
All
Ages:
Between 50 years and 85 years
Trial Updated:
06/27/2023
Locations: University of Iowa Hospitals & Clinics, Iowa City, Iowa
Conditions: Osteo Arthritis Knee, Central Nervous System Sensitization
An Imaging Framework for Clinically Testing New Treatments to Prevent Post-traumatic OA
Recruiting
The immediate goal of the proposed research is to test the value of a new low-cost, low-dose standing CT system for efficient early detection of both joint degeneration and elevated contact stress. The standing CT scanner holds promise for detecting arthritic changes earlier than other imaging modalities because of the combination of its 3D nature and ability to image joints in a weight-bearing pose. A secondary goal of the proposed research is to enable predictive models for osteoarthritis risk... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/10/2023
Locations: University of Iowa Hospitals and Clinics, Iowa City, Iowa
Conditions: Orthopedic Disorder, Trauma, Ankle Fractures, Post-traumatic Osteoarthritis
Evaluation of the Walk With Ease Program for Fall Prevention
Recruiting
The study will use a randomized controlled trial design to evaluate the potential of incorporating physical therapy exercises (primary prevention strategy) within an evidence-based intervention called Walk with Ease to reduce falls and fall risk in older, community-dwelling older adults. The integrated process and outcome evaluation will determine the relative effectiveness of individually prescribed exercises (compared to standardized exercises) as well as the potential of 'habit training' reso... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
02/27/2023
Locations: Department of Kinesiology, Ames, Iowa
Conditions: Exercise, Frailty, Arthritis, Accidental Falls
Lateral Approach Versus Anterior Approach in Total Ankle Replacement
Recruiting
A minimum of 50 patients with ankle end-stage arthritis will be randomized in two parallel groups for surgery. One group will receive a total ankle replacement through an anterior approach and the other group a total ankle replacement via a lateral approach. Patients will be evaluated for a mean follow-up of two years in terms of complications, implant survival and functional results. One of the primary objectives of the study is analyzing the safety of the lateral and anterior approaches for to... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
09/29/2022
Locations: University of Iowa Hospitals & Clinics, Iowa City, Iowa
Conditions: Ankle Osteoarthritis
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