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Diabetes Paid Clinical Trials in Iowa
A listing of 20 Diabetes clinical trials in Iowa actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 20
The state of Iowa currently has 20 active clinical trials seeking participants for Diabetes research studies. These trials are conducted in various cities, including Iowa City, Des Moines, Sioux City and Cedar Rapids.
Featured Trial
Studying an Investigational Treatment in Children with Type 2 Diabetes
Recruiting
The main objectives of this study are to confirm the effectiveness and safety of an investigational treatment in adolescents and children with type 2 diabetes. The study will also assess whether the investigational treatment can improve glucose control and reduce body weight. Participants will be randomly assigned to receive either the investigational treatment or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Pediatric
Type 2 Diabetes (T2DM)
Adolescent Trials
All Conditions
Featured Trial
Heart Failure Clinical Trial
Recruiting
You or someone you love may be eligible for a heart failure clinical study. Eligible participants will receive study-related assessments, care, and treatment at no cost. You may be reimbursed for travel while participating. See if you are eligible.
Conditions:
Heart Failure
Congestive Heart Failure
Chronic Heart Failure
Heart Failure
Congestive
Featured Trial
Studying an Investigational Medication to Manage Pain
Recruiting
This Phase 3 study aims to evaluate the safety and effectiveness of an investigational medication for adults experiencing pain associated with diabetes, specifically in the lower legs. The focus will be on the investigational medication's ability to reduce daily pain levels. Throughout the 14-week study, participants will be randomly assigned to receive either the investigational medication, an already-in-market drug, or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about compensation, study requirements, and risks/benefits. Expressing interest does not commit you to participating in the study; it simply allows you to learn more about it from the research site before making an informed decision.
Conditions:
All Conditions
Diabetic peripheral neuropathy (DPN)
Diabetes
Featured Trial
Assessing an Investigational Medication on Major Adverse Cardiovascular Events Such as Heart Attack and Stroke
Recruiting
The main purpose of this study is to evaluate the cardiovascular safety of the investigational medication compared with a placebo in participants who are at an increased risk of adverse cardiovascular outcomes (ie. heart attack and stroke). Participants will be randomly assigned to receive either the investigational medication or a placebo, with safety and tolerability being monitored throughout. Should you express interest, you will be contacted directly by the research site, who will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Ischemic heart disease (IHD)
Overweight
Metabolic syndrome
Diabetes related diseases
Cardiovascular Disease
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Studying an Investigational Vaccine for a Common Herpesvirus in Adolescents
Recruiting
This study aims to evaluate the safety, effectiveness, and immune response of an investigational vaccine targeting cytomegalovirus (CMV), a common type of herpesvirus. Participants will be randomly assigned to receive either the investigational vaccine or a placebo. The study will monitor participants’ health and immune response over an 18-month period. Should you express interest for the adolescent in your care, you will be contacted directly by the research site. They will provide further details and address any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Preventative Trials
Healthy
All Conditions
Parent / Carer of child aged 0-17
A Research Study to See How Much CagriSema (1.0 mg Once Weekly) Lowers Blood Sugar and Body Weight Compared to Tirzepatide (5 mg Once Weekly) in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both
Recruiting
This study will look at how much CagriSema lowers blood sugar and body weight in people with type 2 diabetes. CagriSema is a new investigational medicine. Doctors cannot yet prescribe CagriSema. CagriSema will be compared to a medicine called tirzepatide. Doctors can prescribe tirzepatide in some countries. Participants will either receive CagriSema or tirzepatide. Which treatment the participant will receive is decided by chance. For each participant, the study will last for up to 1 year and 4... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/12/2025
Locations: Iowa Diabetes & Endo Res Ctr, West Des Moines, Iowa
Conditions: Diabetes Mellitus, Type 2
A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma
Recruiting
This phase II trial studies how well lower dose radiotherapy after chemotherapy (Carboplatin \& Etoposide) works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by... Read More
Gender:
ALL
Ages:
Between 3 years and 29 years
Trial Updated:
02/11/2025
Locations: University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa
Conditions: Central Nervous System Germinoma, Diabetes Insipidus, Pineal Region Germinoma, Suprasellar Germinoma, Basal Ganglia Germinoma, Thalamic Germinoma
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Recruiting
TRANSFORM is a prospective, randomized, open blinded endpoint (PROBE), event-driven, pragmatic trial in patients who are at increased risk for atherosclerotic cardiovascular (CV) disease but with no known symptomatic CV disease. The trial tests the hypothesis that a Cleerly Coronary Artery Disease (CAD) Staging System-based care strategy reduces CV events compared with risk factor-based care.
Gender:
ALL
Ages:
55 years and above
Trial Updated:
02/10/2025
Locations: MercyOne Iowa Heart Center, West Des Moines, Iowa
Conditions: Diabetes Mellitus, Type 2, PreDiabetes, Metabolic Syndrome
A Study of CT-388 in Participants Who Are Overweight or Obese with Type 2 Diabetes Mellitus
Recruiting
This is a multi-center, randomized, double-blind, placebo-controlled, parallel group dose-finding study to evaluate the efficacy and safety of CT-388 at low, middle, and high doses in participants who are overweight or obese with Type 2 diabetes mellitus (T2DM).
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/07/2025
Locations: McFarland Clinic, Ames, Iowa
Conditions: Overweight or Obese, Type 2 Diabetes Mellitus (T2DM)
A Study Called FINE-REAL to Learn More About the Use of the Drug Finerenone in a Routine Medical Care Setting
Recruiting
This is an observational study in people with chronic kidney disease (CKD) and type 2 diabetes (T2D) who will be receiving finerenone.
Kidneys filter extra water and waste out of the blood and make urine. CKD is a long-term, progressive, decrease in the kidneys' ability to filter the blood properly. In people with T2D, the body does not make enough of a hormone called insulin, or does not use insulin well enough, resulting in high blood sugar levels that can cause damage to the kidneys. As a re... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/03/2025
Locations: University of Iowa Preventive Intervention Clinic, Iowa City, Iowa
Conditions: Chronic Kidney Disease, Type 2 Diabetes Mellitus
A Study of Investigational Tirzepatide (LY3298176) Doses in Participants With Type 2 Diabetes and Obesity
Recruiting
The main purpose of this study is to learn more about the safety and efficacy of investigational tirzepatide doses in participants with Type 2 diabetes and obesity that are already taking metformin. The study will last for about 89 weeks.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
01/22/2025
Locations: Integrated Clinical Trial Services, Inc., West Des Moines, Iowa
Conditions: Type 2 Diabetes, Obesity
A Study to Learn How Well the Study Treatment Finerenone Works and How Safe it is in People With Long-term Decrease in the Kidneys' Ability to Work Properly (Chronic Kidney Disease) Together With Type 1 Diabetes
Recruiting
Researchers are looking for a better way to treat people with chronic kidney disease (CKD), a progressive decrease in the kidneys' ability to work properly, and type 1 diabetes.
In people with type 1 diabetes, the body does not make enough of a hormone called insulin, resulting in high blood sugar levels that can cause damage to the kidneys. CKD often occurs together with or as a consequence of type 1 diabetes.
The study treatment finerenone works by blocking certain proteins, called mineraloc... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/20/2025
Locations: University of Iowa Hospitals & Clinics, Iowa City, Iowa
Conditions: Chronic Kidney Disease, Type 1 Diabetes Mellitus
A Phase III Study to Investigate If the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed with Type 1 Diabetes
Recruiting
The objective of DIAGNODE-3 is to evaluate the efficacy and safety of three intranodal injections of 4 μg of Diamyd compared to placebo, along with oral Vitamin D supplementation, to preserve endogenous beta cell function and influence glycemic parameters in adolescent and adults recently diagnosed with T1D carrying the HLA DR3-DQ2 haplotype.
Gender:
ALL
Ages:
Between 12 years and 28 years
Trial Updated:
01/17/2025
Locations: University of Iowa Hospital and Clinics, Iowa City, Iowa
Conditions: Type 1 Diabetes Mellitus
SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
Recruiting
The purpose of this single-arm interventional study is to evaluate the long-term safety, efficacy, and durability of the Symplicity Spyral system in subjects treated with renal denervation.
Additionally, long-term follow-up data will also be collected from eligible subjects previously treated in the SPYRAL PIVOTAL-SPYRAL HTN-OFF MED and SPYRAL HTN-ON MED studies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/16/2025
Locations: Mercy Medical Center, West Des Moines, Iowa
Conditions: Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
Metformin for the Treatment of Microvascular Dysfunction After Gestational Diabetes
Recruiting
The purpose of this investigation is to examine the mechanisms mediating vascular dysfunction in women who have had gestational diabetes and how metformin may be a valuable treatment tool to improve microvascular function in these women before the onset of disease.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
12/19/2024
Locations: University of Iowa, Iowa City, Iowa
Conditions: Gestational Diabetes
Role of NADPH Oxidase in Microvascular Dysfunction Following GDM
Recruiting
The purpose of this investigation is to examine NADPH oxidase as a source of reactive oxygen species contributing to aberrant microvascular function in otherwise healthy women with a history of GDM.
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
11/27/2024
Locations: University of Iowa, Iowa City, Iowa
Conditions: Gestational Diabetes, Oxidative Stress, Vascular Endothelial Function
Role of ET-1, Physical Activity, and Sedentary Behavior in Microvascular Dysfunction Following GDM
Recruiting
Women with a history of gestational diabetes mellitus (GDM) are at a 2-fold greater risk for the development of overt cardiovascular disease (CVD) following the effected pregnancy. While subsequent development of type II diabetes elevates this risk, prior GDM is an independent risk factor for CVD morbidity, particularly, within the first decade postpartum. GDM is associated with impaired endothelial function during pregnancy and decrements in macro- and microvascular function persist postpartum,... Read More
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
11/25/2024
Locations: University of Iowa, Iowa City, Iowa
Conditions: Gestational Diabetes, Endothelial Dysfunction, Physical Inactivity