The state of Kansas currently has 7 active clinical trials seeking participants for Osteoarthritis research studies. These trials are conducted in various cities, including Wichita, Kansas City, Overland Park and Topeka.
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
Recruiting
The purpose of the chronic pain master protocol is to compare independent pain interventions and establish an overarching structure for the disease-state addenda (DSA) and intervention-specific appendices (ISAs). The ISAs may start independently of other ISAs as interventions become available for clinical testing.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Cotton O'Neil Clinical Research Center - Central Office, Topeka, Kansas
Conditions: Osteoarthritis, Knee, Diabetic Neuropathic Pain, Chronic Low-back Pain
A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight
Recruiting
The purpose of this study is to evaluate the efficacy and safety of retatrutide in participants who have obesity or overweight (J1I-MC-GZBJ master protocol) including subsets of participants who have knee osteoarthritis (OA) (J1I-MC-GOA1) or who have obstructive sleep apnea (OSA) (J1I-MC-GSA1). This study will last about 89 weeks and will include up to 24 visits.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/29/2024
Locations: Cotton O'Neil Clinical Research Center, Topeka, Kansas
Conditions: Obesity, Overweight, Knee Pain Chronic, Knee Osteoarthritis, Obstructive Sleep Apnea
A Safety and Efficacy Study of Anti-inflammatory (Canakinumab) and Cartilage Stimulating (LNA043) Drugs Injected Into the Knee Joint of Participants With Knee Osteoarthritis (OA)
Recruiting
The study will establish safety and efficacy of canakinumab and LNA043 in patients with knee osteoarthritis (OA).
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
01/30/2024
Locations: Novartis Investigative Site, Kansas City, Kansas
Conditions: Knee Osteoarthritis
Open-label Trial to Check the Safety and Tolerability of RTX-GRT7039 Injections for Pain Associated With Osteoarthritis of the Knee
Recruiting
An open-label, single-arm clinical trial to confirm the safety of monoarticular injections or bi-lateral intra-articular injections of RTX-GRT7039 in patients who have pain associated with osteoarthritis of the knee despite standard of care.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/25/2023
Locations: University Of Kansas Medical Center, Kansas City, Kansas +1 locations
Conditions: Osteoarthritis
Knee Arthroplasty Activity Trial
Recruiting
Total knee replacement (TKR) is a common and costly procedure widely used to relieve pain and improve function in patients with symptomatic advanced knee osteoarthritis (OA). As of 2013, the annual incidence of TKR was over 680,000 surgeries and annual costs exceeded $11 billion. Growing evidence suggests that while pain and functional status improve following TKR, physical activity (PA) typically does not surpass pre-TKR levels. Engagement in PA can meaningfully improve quality of life (QoL), p... Read More
Gender:
All
Ages:
Between 40 years and 85 years
Trial Updated:
08/17/2023
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Knee Osteoarthritis, Total Knee Replacement
Investigating the Effect of Interval Walking and Qigong on People With Knee Osteoarthritis: Pilot Study
Recruiting
Knee osteoarthritis (KOA) causes pain and limited function that leads to a sedentary lifestyle. The sedentary lifestyle increases the risk of cardiovascular diseases. In addition, many subjects with KOA have knee pain and sleep disturbance that limit their function, quality of life and cause body fatigue. Walking exercise can benefit people with KOA. However, continues walking for more than 30 minutes can increase pain that may stop people from participation in walking exercise. Interval walkin... Read More
Gender:
All
Ages:
Between 45 years and 79 years
Trial Updated:
05/19/2022
Locations: Wen Liu, Kansas City, Kansas
Conditions: Osteoarthritis, Knee
Treatment Effects of Subcutaneous Injections of Pentosan Polysulfate Sodium vs Placebo in Participants With Knee OA Pain
Recruiting
The purpose of this study is to measure the change in pain and function with subcutaneous injections of pentosan polysulfate sodium (PPS) compared with subcutaneous injections of placebo in participants with knee osteoarthritis pain. Study details include: The study duration will be up to 28 weeks per participant The treatment duration will be 6 weeks. The visit frequency will be twice weekly during treatment..
Gender:
All
Ages:
18 years and above
Trial Updated:
03/31/2022
Locations: Alliance for Multispecialty Research - Newton, Newton, Kansas +2 locations
Conditions: Osteoarthritis, Knee