The city of Lexington, Kentucky, currently has 4 active clinical trials seeking participants for Type 2 Diabetes research studies.
A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Recruiting
This study is open to adults with type 2 diabetes, high blood pressure, and cardiovascular disease. People can join the study if they have these conditions and do not have a history of heart failure. The purpose of this study is to find out if a medicine called vicadrostat, when taken with empagliflozin, helps reduce cardiovascular risk in people with these conditions. The study will compare this combination to a placebo version of vicadrostat with empagliflozin. Participants are put into 2 gro... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2025
Locations: The Research Group of Lexington, Lexington, Kentucky
Conditions: Diabetes Mellitus, Type 2, Hypertension, Cardiovascular Diseases
Promoting Intergenerational Health in Rural Kentuckians With Diabetes (PIHRK'D)
Recruiting
The goal of this feasibility study is to use family units as support to promote nutrition and physical activity of individuals with type 2 diabetes. The main question it aims to answer is: • How does the family structure impact the health of its members living with type 2 diabetes? Participants will be asked to; * Tell us about their access to food sources and places in the community to engage in physical activity. * A nutrition and physical activity plan will be developed for participants an... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/17/2025
Locations: University of Kentucky, Lexington, Kentucky
Conditions: Diabetes Mellitus, Type 2
A Causative Role for Amylin in Diabetic Peripheral Neuropathy
Recruiting
Three pieces of information lead to the basis for this study: 1. Individuals with Type-2 diabetes commonly develop peripheral neuropathy. 2. Increased production of the hormone amylin occurs in individuals who have Type-2 diabetes. 3. Aggregations of amylin was found in the peripheral vasculature of rats that overexpressed human amylin. The purpose of this study is to determine whether a correlation exists between the amount of amylin present in the upper extremities of human subjects with Typ... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/15/2025
Locations: UK Robert Straus Behavioral Science Laboratory, Lexington, Kentucky +1 locations
Conditions: Type2 Diabetes, Peripheral Neuropathy
BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes
Recruiting
An observational study of electronic patient data to compare diabetes medications and to determine which ones offer the best balance of risks and benefits.
Gender:
ALL
Ages:
30 years and above
Trial Updated:
06/16/2023
Locations: Humana, Lexington, Kentucky
Conditions: Diabetes Mellitus, Type 2