There are currently 632 clinical trials in Louisville, Kentucky looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Louisville, Jewish Hospital, Norton Cancer Institute and Saints Mary and Elizabeth Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Direct Application of Integra Bilayer Matrices on Bare Calvarium Without Preliminary Burring
NCT05311124
Recruiting
This study is to determine if large, full thickness scalp wounds with exposed calvarium resulting from acutely created extirpative defects can be reliably and durably resurfaced with IDRT without burring or fenestration as a preliminary step, regardless of the size of the calvarial defect.
Gender:
All
Ages:
Between 55 years and 100 years
Trial Updated:
10/17/2022
Locations: University of Louisville School of Medicine Division of Plastic Surgery, Louisville, Kentucky
Conditions: Wound Care, Pressure Ulcer, Venous Ulcer, Surgical Wound, Trauma Wounds, Draining Wound
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Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry
NCT04669548
Recruiting
The Accuryn Registry Study is an open-ended, global, multi-center, retrospective and prospective, single-arm data collection study with an FDA cleared device. The target population are cardiovascular surgery patients. Physiologic data measurements will be collected from enrolled subjects using electronic medical records and data streams via the Accuryn Monitoring System.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/26/2022
Locations: Jewish Hospital / University of Louisville, Louisville, Kentucky
Conditions: Intraabdominal Hypertension, Abdominal Compartment Syndrome, Acute Kidney Injury, Cardiovascular Surgery
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Peppermint Oil for the Treatment of Interstitial Cystitis / Bladder Pain Syndrome
NCT04845217
Recruiting
The purpose of this study is to assess the use of peppermint oil as a treatment for Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS).
Gender:
Female
Ages:
Between 18 years and 65 years
Trial Updated:
08/19/2022
Locations: Springs Medical Center, Louisville, Kentucky
Conditions: Interstitial Cystitis
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Assessment of Anti-tumor and Safety in Glumetinib in Patients With c-MET-positive Non-Small Cell Lung Cancer
NCT04270591
Recruiting
Indication:Patients with Advanced c-MET-positive Non-Small Cell Lung Cancer Phase Ib (China only): Approximately 90 patients Phase Ⅱ (globally): Approximately 78 evaluable patients; addition of at least 6 patients in Safety Run-in (US only)
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
07/28/2022
Locations: Norton Cancer Institute, Louisville, Kentucky +1 locations
Conditions: C-Met Exon 14 Mutation
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Treatment Study of AV Node Reentry Tachycardia
NCT04232371
Recruiting
Compare the effectiveness and safety of two techniques for modification of slow AV nodal pathway conduction underlying AVNRT: 1) New Ablation Technique, low voltage and wave front collision mapping vs. 2) the Standard Ablation Technique, an anatomical/electrogram approach.
Gender:
All
Ages:
21 years and below
Trial Updated:
07/26/2022
Locations: University of Louisville, Louisville, Kentucky
Conditions: Supraventricular Tachycardia
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A Phase 1b Study of a Q-Griffithsin Intranasal Spray for Broad-spectrum Coronavirus Prophylaxis
NCT05437029
Recruiting
The purpose of this study is to test the safety of multiple doses of a Q-GRFT nasal spray in healthy volunteers. This Q-GRFT nasal spray is "investigational and not approved by the FDA for general use" and is being developed to prevent the transmission of COVID-19 and other coronaviruses.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
06/27/2022
Locations: University of Louisville Clinical Trials Unit, Louisville, Kentucky
Conditions: COVID-19 Prevention
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Fish Oil in Total Hip Replacement Randomized Clinical Trial
NCT04360239
Recruiting
The purpose of this study is to determine if continuing fish oil supplementation leads to higher blood loss in patients undergoing total hip arthroplasty (THA). Another purpose is to determine if patients on fish oil have less pain after THA. Fish oil (Omega-3 fatty acid) is commonly used by patients as a natural anti-inflammatory to decrease joint pain from arthritis. Supplements, including fish oil, are typically stopped 1-2 weeks prior to surgery as there is an increased risk of perioperative... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
06/03/2022
Locations: Norton Healthcare, Louisville, Kentucky
Conditions: Total Hip Arthroplasty
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The Effect of Beta-glucan in Non-Small Cell Lung Cancer
NCT00682032
Recruiting
The purpose of this study is to determine how beta-glucan affects the immune system in subjects with non-small cell lung cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/05/2022
Locations: James Graham Brown Cancer Center, Louisville, Kentucky
Conditions: Non Small Cell Lung Cancer
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A Study to Evaluate the Efficacy and Safety of Rosnilimab (ANB030) in Treatment of Subjects With Moderate-to-Severe Alopecia Areata
NCT05205070
Recruiting
Efficacy and safety of rosnilimab (ANB030) in subjects with moderate-to-severe Alopecia Areata
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/03/2022
Locations: Site 10-116, Louisville, Kentucky
Conditions: Alopecia Areata
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NSAIDS vs Opioids in Tibial Fractures
NCT05332314
Recruiting
This study will attempt to determine if there is a statistic difference between the time to union, non-union rate and post-operative pain of patients who receive opioids for pain control vs. patients who receive NSAIDs and a reduced dosage of opioids for pain management
Gender:
All
Ages:
Between 18 years and 105 years
Trial Updated:
04/15/2022
Locations: University of Louisville Hospital, Louisville, Kentucky +1 locations
Conditions: Trauma
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Pilot Study for Feasibility of Using an Oral Appliance for Decreasing Snoring
NCT04900285
Recruiting
This research study proposes to determine how well tolerated and effective lower and upper oral dental devices are at reducing snoring. The device is designed to move the genioglossus muscle forward, with interior attachment to maintain forward placement of of he tongue on the bottom of the mouth.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
04/05/2022
Locations: Norton Clinical Research Group, Louisville, Kentucky
Conditions: Snoring
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PSB202 in Patients With Previously Treated-, Relapsed-, Indolent B-Cell Malignancies
NCT05003141
Recruiting
Product: PSB202 is a novel biological entity consisting of two engineered monoclonal antibodies, an Fc-enhanced humanized type II anti-CD20 IgG1 (PSB102) and a humanized anti-CD37 IgG1 (PSB107), that target B-cells. PSB202 is manufactured to work as a single product with the two components of PSB202 enabling a distinct dual target-specific antibody directed cell killing of B-cells. Study: Multi-center-, International Phase 1a/1b (Escalation/Expansion) study in patients with indolent-, relapsed-... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2022
Locations: Norton Cancer Institute, Louisville, Kentucky
Conditions: Follicular Lymphoma, Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Waldenstrom Macroglobulinemia, Marginal Zone Lymphoma, Mantle Cell Lymphoma, Indolent Lymphoma, Refractory B-Cell Lymphoma, MALT Lymphoma
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