The state of Maryland currently has 8 active clinical trials seeking participants for Diabetic Macular Edema research studies. These trials are conducted in various cities, including Baltimore, Bethesda, Rockville and Annapolis.
A Study to Evaluate the Efficacy and Safety of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DME
Recruiting
EYE-RES-102 is a randomized, double masked pivotal study to evaluate the efficacy and safety of 2 dose levels of EYE103 in comparison with the active control, ranibizumab, in patients with diabetic macular edema (DME) In the first year, all 3 treatment groups will be treated every 4 weeks with either EYE103 or ranibizumab. Beginning at Year 2, the frequency of treatment for participants will shift based on a personalized treatment interval algorithm. Approximately 960 participants will be ente... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/27/2025
Locations: Hagerstown, MD, Hagerstown, Maryland
Conditions: Diabetic Macular Edema (DME)
Study to Assess the Efficacy & Safety of KHK4951 in Patients With Diabetic Macular Edema
Recruiting
The purpose of this study is to evaluate efficacy and safety of KHK4951 eye drops in patients with DME.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/16/2025
Locations: Mid Atlantic Retina Specialists - Hagerstown, Hagerstown, Maryland
Conditions: Diabetic Macular Edema (DME)
A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented Patients With Diabetic Macular Edema
Recruiting
This study is designed to investigate treatment response in treatment-naïve underrepresented patients with diabetic macular edema (DME) who are treated with faricimab. The study population will consist of participants ≥18 years of age who self-identify as Black/African American, Hispanic/Latino American, or Native American/Alaska Native/Native Hawaiian or other Pacific Islander; in addition, a cohort of Asian Indian participants will be enrolled in India.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/16/2025
Locations: Wilmer Eye Institute Johns Hopkins University, Baltimore, Maryland +1 locations
Conditions: Diabetic Macular Edema
A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products
Recruiting
The VOYAGER study is a primary data collection, non-interventional, prospective, multinational, multicenter study. It is designed to collect real-world, long-term data to explore long-term effectiveness, safety, clinical insights, treatment patterns, and factors driving the treatment decisions among patients being treated with specified Roche ophthalmology products in approved retinal indications (Faricimab for neovascular age-related macular degeneration \[nAMD\], diabetic macular edema \[DME\]... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/10/2025
Locations: Cumberland Valley Retina Consultants PC, Hagerstown, Maryland
Conditions: Neovascular Age-related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion, Branch Retinal Vein Occlusion, Central Retinal Vein Occlusion, Hemi-retinal Vein Occlusion
A Phase 3b, Single-Arm Study of Aflibercept 8 mg Dosed Every 4 Weeks in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) or Diabetic Macular Edema (DME)
Recruiting
This study is researching aflibercept high dose (HD), referred to as "study drug", with an experimental dosing regimen. The study is focused on participants with nAMD and DME that have been previously treated with anti-vascular endothelial growth factor (anti-VEGF) medications. The aim of the study is to see how safe and effective aflibercept HD injections are when given as frequently as every 4 weeks. The study is also looking at what side effects may happen from taking the study drug.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/09/2025
Locations: Mid Atlantic Retina Specialists, Hagerstown, Maryland
Conditions: Neovascular Age-Related Macular Degeneration, Diabetic Macular Edema
4D-150 in Patients With Diabetic Macular Edema
Recruiting
Phase 2 randomized, active-controlled, double-masked, dose-ranging trial in adults with Diabetic Macular Edema (DME).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: Cumberland Valley Retina Consultants, Hagerstown, Maryland
Conditions: Diabetic Macular Edema, Diabetic Retinopathy
Study of EYP-1901 in Patients With Diabetic Macular Edema (DME)
Recruiting
A prospective, randomized, single-masked study evaluating the ocular efficacy and safety of two doses of the EYP-1901 intravitreal insert compared to aflibercept
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/17/2024
Locations: EyePoint Investigative Site, Hagerstown, Maryland
Conditions: Diabetic Macular Edema
Evaluation of Repeated, In-Clinic, Self-Imaging by DME Patients Using the Notal Vision Home OCT
Recruiting
Evaluation of Repeated, In-Clinic, Self-Imaging by DME Patients Using the Notal Vision Home OCT The purpose of this study is to collect data on the NVHO device at up to three sites.
Gender:
All
Ages:
All
Trial Updated:
02/15/2023
Locations: Elman Retina Group, PA, Baltimore, Maryland
Conditions: Diabetic Macular Edema