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Depression Paid Clinical Trials in Massachusetts
A listing of 37 Depression clinical trials in Massachusetts actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 37
The state of Massachusetts currently has 37 active clinical trials seeking participants for Depression research studies. These trials are conducted in various cities, including Boston, Worcester, Springfield and Burlington.
Featured Trial
Cardiovascular Disease Trials
Recruiting
Cardiovascular Disease trials near you are looking for participants to help push medical research forward. Click through to learn more!
Conditions:
Cardiovascular Disease
Featured Trial
High Triglyceride Clinical Research Study
Recruiting
Living with high triglycerides? See if our clinical study is right for you.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Conditions:
High Triglycerides
High Triglyceride Level
Hypertriglyceridemia
Elevated Triglycerides
Triglycerides High
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Chronic Cough Clinical Study
Recruiting
We are evaluating an investigational treatment to see if it may help people dealing with chronic cough.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required. If you qualify, you may receive:
Payment up to $1500, which varies by study.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required. If you qualify, you may receive:
Payment up to $1500, which varies by study.
Conditions:
Cough
Chronic Cough
Asthma
Allergic Asthma
Sinusitis
Featured Trial
Healthy Volunteer Trials
Recruiting
Healthy trials near you are looking for participants to help push medical research forward. Click through to learn more!
Conditions:
Healthy
Efficacy, Safety, and Tolerability of COMP360 in Participants With TRD
Recruiting
Efficacy, Safety, and Tolerability of a single administration of COMP360 in participants with treatment-resistant depression (TRD)
Gender:
All
Ages:
18 years and above
Trial Updated:
06/21/2024
Locations: University of Massachusetts Medical School, North Worcester, Massachusetts
Conditions: Treatment Resistant Depression
The Ukrainian Student Problem Solving Project
Recruiting
The purpose of this study is to test the effectiveness of a universal, digital, single-session intervention for youth mental health, functioning, and well-being. The investigators will be providing access to a brief online program (Project SOLVE) for students as part of the school curriculum. Ukrainian students living in Poland will be randomly assigned to receive Project SOLVE either immediately or after 3 months. The program is designed to help students manage stress and reach their academic a... Read More
Gender:
All
Ages:
Between 10 years and 18 years
Trial Updated:
06/14/2024
Locations: Harvard University, Cambridge, Massachusetts
Improving Preschool Outcomes by Addressing Maternal Depression in Head Start
Recruiting
Within a research network of Head Start centers in Massachusetts, an efficacy trial of a stepped-care intervention (SCI) to address maternal depression, using intervention components that both prevent depression and help those in major depressive episode (MDE) engage with care, will be conducted. Both the prevention and engagement components of the model have strong, supportive randomized trial evidence for both their efficacy and safety; but they have yet to be synthesized and tested within a c... Read More
Gender:
Female
Ages:
All
Trial Updated:
06/14/2024
Locations: Boston Medical Center, Boston, Massachusetts
Conditions: Maternal Depression
Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV
Recruiting
This study will determine the effects of pregnenolone on brain function, inflammation and depressive symptoms in people with HIV who have depression. Participants in this study will receive a pill of either pregnenolone or placebo, and can stay on their current antidepression medications. Brain imaging and behavioral assessments will be performed during the study.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
06/07/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Major Depressive Disorder, Anxiety Depression, Hiv
Toward Understanding Drivers of Patient Engagement With Digital Mental Health Interventions - Part II
Recruiting
This study is a clinical trial that evaluates what drives patient engagement and tests the impact of two strategies-automated motivational push messaging and coach support-to improve engagement with an evidence-based mobile app intervention for depression and/or anxiety.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
06/05/2024
Locations: Jessica Morrow Lipschitz, Boston, Massachusetts
Conditions: Depression, Anxiety Disorders
Mobile Mental Health Stigma Reduction Intervention Among Black Adults
Recruiting
Major depressive and anxiety disorders are highly prevalent in the general population and are a leading cause of disability. Black adults have a high burden of depression and anxiety. This study aims to assess a self- administered video-based intervention to reduce mental illness stigma and medical mistrust among Black adults with moderate to severe depression or anxiety.
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
04/10/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Anxiety, Depression, Health Knowledge, Attitudes, Practice, Stigmatization, Mobile Phone Use
Mindfulness-Based fMRI Neurofeedback for Depression
Recruiting
In the United States, adolescents experience alarmingly high rates of major depression, and gold-standard treatments are only effective for approximately half of patients. Rumination may be a promising treatment target, as it is well-characterized at the neural level and contributes to depression onset, maintenance, and recurrence as well as predicts treatment non-response. Accordingly, the proposed research will investigate whether an innovative mindfulness-based real-time functional magnetic r... Read More
Gender:
All
Ages:
Between 13 years and 18 years
Trial Updated:
04/09/2024
Locations: Northeastern University, Boston, Massachusetts
Conditions: Depression in Adolescence, Rumination
Buspirone and Melatonin for Depression Following Traumatic Brain Injury
Recruiting
Traumatic brain injuries (TBIs) are common. Post-TBI depression is associated with anxiety, aggression, fatigue, distractibility, anger, irritability, and rumination. The current research group conducted a pilot clinical trial, which investigated the novel treatment combination of buspirone and melatonin (B+MEL) in outpatients with clinical depression. Compared to placebo, B+MEL was associated with a significant improvement in depressive symptoms. Depression following TBI may be different from c... Read More
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
04/09/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts +1 locations
Conditions: Depression, Brain Injuries, Traumatic
Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder
Recruiting
This is a randomized, double-blind, placebo-controlled proof-of-concept clinical trial to assess the efficacy and safety of Magnesium-vitamin B6in combination with treatment as usual for treating symptoms of depression, stress, and anxiety in patients with first episode bipolar I disorder.
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
03/28/2024
Locations: McLean Hospital, Belmont, Massachusetts
Conditions: Bipolar I Disorder, Depression, Anxiety, Stress
Mechanism of Action of Electroconvulsive Therapy
Recruiting
This is an observational neuroimaging study assessing the effects of ECT on the brains of patients with unipolar and bipolar depression.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/20/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Unipolar Depression, Bipolar Depression
Early Life Stress and Depression: Molecular and Functional Imaging
Recruiting
Severe childhood adversity accounts for a large portion of psychiatric illness, and an increased risk for major depressive disorder (MDD). For some individuals, childhood adversity has negative psychological and medical consequences; others preserve mental and physical health despite such experiences (they are resilient). In spite of this, little is known about the neurobiological mechanisms related to childhood adversity, especially oxidative stress abnormalities in the brain. To fill this gap,... Read More
Gender:
Female
Ages:
Between 20 years and 32 years
Trial Updated:
03/11/2024
Locations: McLean Hospital, Belmont, Massachusetts
Conditions: Depression, Trauma, Psychological
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
Recruiting
Objectives of this study are to determine whether active VNS Therapy treatment is superior to a no stimulation control in producing a reduction in baseline depressive symptom severity, based on multiple depression scale assessment tools at 12 months from randomization.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Treatment Resistant Depression
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