The state of Massachusetts currently has 138 active clinical trials seeking participants for Lung Cancer research studies. These trials are conducted in various cities, including Boston, Worcester, Springfield and Burlington.
Diagnostic Performance of Small RNA Blood Test in Patients Undergoing Follow-up Imaging After Positive Low Dose CT Screening for Cancer of the Lung
NCT05987189
Recruiting
2,000 individuals, aged 50-80 who have received a lung-RADS category 3 or 4 result on a LDCT screening study and who are scheduled for follow-up diagnostic imaging study, biopsy, clinical consultation or surgical appointment at one of the participating hospitals.
Gender:
ALL
Ages:
Between 50 years and 80 years
Trial Updated:
01/12/2024
Locations: Mass General Brigham, Boston, Massachusetts
Conditions: Lung Cancer
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Prospective Collection of Whole Blood From Active Non-Small Cell Lung Cancer Patients for Supplemental Research
NCT05669105
Recruiting
The study objective is to collect biospecimen samples (e.g., whole blood) from participants diagnosed with active lung cancer to investigate the immune response to develop treatments and therapies.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
11/20/2023
Locations: Sanguine Biosciences, Waltham, Massachusetts
Conditions: Non Small Cell Lung Cancer
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Lung Cancer Risk and Early Detection in Firefighters
NCT04614129
Recruiting
This study will evaluate whether LDCT findings differ between firefighters and non-fighters, the relationship between occupational exposures and LDCT findings, and whether a proteomics assay can further risk-stratify screen-detected nodules among a study population of 850 current and retired firefighters and 1,120 matched controls.
Gender:
ALL
Ages:
Between 40 years and 80 years
Trial Updated:
09/21/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Lung Cancer, Lung Diseases
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Adapting the Tumor Board Model for Mental Illness and Cancer
NCT05837598
Recruiting
This study examines the feasibility and acceptability of a virtual tumor board for cancer and mental illness for patients with serious mental illness and a new cancer diagnosis. The study also examines the impact on patient care, psychiatric symptoms, and clinician self-efficacy in managing this population.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/01/2023
Locations: Mass General/North Shore Center for Outpatient Care, Danvers, Massachusetts
Conditions: Cancer, Severe Major Depression, Schizophrenia, Bipolar Disorder, Lung Cancer, Breast Cancer, Head and Neck Cancer, Gastrointestinal Cancer, Genitourinary Cancer
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A Dose Escalation With Expansion Study of EMB-01 in Participants With Advanced/Metastatic Solid Tumors
NCT03797391
Recruiting
First-in-human, Phase I/II, Multicenter, Open-Label Study of EMB-01 in Patients with Advanced/Metastatic Solid Tumors
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/30/2023
Locations: Dana-Farber Cancer Institute, Boston, Massachusetts
Conditions: Neoplasms, Neoplasm Metastasis, Non-Small-Cell Lung Cancer
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Evaluation of PET Probe [68Ga]CBP8 in the Detection of Radiation Induced Tissue Injury
NCT04485286
Recruiting
The goal of this study is to investigate the efficacy of \[68Ga\]CBP8 to detect collagen deposition in radiation induced tissue injury.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
04/30/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Lung Cancer, Radiation Fibrosis, Radiation Induced Lung Injury, Pancreas Cancer
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