The state of Massachusetts currently has 139 active clinical trials seeking participants for Lung Cancer research studies. These trials are conducted in various cities, including Boston, Worcester, Springfield and Burlington.
Study of RET Inhibitor TAS0953/HM06 in Patients With Advanced Solid Tumors With RET Gene Abnormalities
NCT04683250
Recruiting
Phase 1 and 2 trial to study the safety, pharmacokinetics, and efficacy of TAS0953/HM06 in patients with advanced solid tumors with RET gene abnormalities. Phase 1 aims to determine the Maximum Tolerated Dose (MTD) and identify the Recommended Phase 2 Dose (RP2D) to be used in phase 2.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/02/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: RET-altered Non Small Cell Lung Cancer, RET-altered Solid Tumors
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Image Guided VATS vs. VATS Resection
NCT03623958
Recruiting
To evaluate workflow and outcomes of iVATS and standard VATS for small pulmonary nodules. The outcomes of the patients will be evaluated separately as there will be no direct comparison of the two arms.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/06/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Lung Cancer
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The Transitions Project: Efficacy Trial
NCT05087251
Recruiting
The aim of this study is to evaluate the efficacy of a brief psychoeducational intervention to improve quality of life in patients with lung cancer who are transitioning from active treatment to surveillance.
Gender:
All
Ages:
21 years and above
Trial Updated:
11/09/2022
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts +1 locations
Conditions: Lung Cancer
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Pilot Study of Biopsy Scanner for Evaluation of Bronchoscopic Small Biopsy Specimens to Determine Adequacy
NCT05393154
Recruiting
The aim of the study is to assess the performance of Aquyre Biopsy Scanner technology (the FDA class I medical device) at determining if tissue from the lymph nodes and lung nodules, taken during a bronchoscopy procedure, is adequate for a diagnosis. The study will assess how well the Aquyre Biopsy Scanner can differentiate between tissue samples that meet certain requirements that allow for further diagnostic analysis and samples that do not.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/24/2022
Locations: Boston Medical Center, Boston, Massachusetts
Conditions: Lung Cancer
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DNA Analysis of Blood and Tissue From Patients With Lung Cancer
NCT00471978
Recruiting
RATIONALE: Studying samples of blood and tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help the study of cancer in the future. PURPOSE: This clinical trial is analyzing the DNA in blood and tissue samples from patients with lung cancer.
Gender:
All
Ages:
Between 18 years and 120 years
Trial Updated:
04/14/2022
Locations: Massachusetts General Hospital, Boston, Massachusetts +1 locations
Conditions: Lung Cancer
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Molecular and Genetic Analysis of Lung Cancer
NCT03029325
Recruiting
Investigators use a genome-wide approach within a case-control design to identify SNPs that show evidence of association with lung cancer risk and survival.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/14/2022
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Lung Cancer
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Niraparib in Combination With Osimertinib in EGFR-Mutated Advanced Lung Cancer
NCT03891615
Recruiting
This research study is studying a combination of drugs as a possible treatment for EGFR-Mutated Advanced Lung Cancer. The names of the study drugs involved in this study are Niraparib and Osimertinib.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/14/2020
Locations: Dana Farber Cancer Institute, Boston, Massachusetts +2 locations
Conditions: Lung Cancer
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