There are currently 967 clinical trials in Ann Arbor, Michigan looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Michigan, University of Michigan Comprehensive Cancer Center, University of Michigan Health System and C S Mott Children's Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
LowSalt4Life: A Mobile Application to Reduce Sodium Intake And Blood Pressure
NCT05396001
Recruiting
This research is being done to learn if a smartphone app with and without a just in time adaptive intervention (JITAI) can help patients with hypertension manage their sodium intake and improve their blood pressure.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/21/2024
Locations: The University of Michigan, Ann Arbor, Michigan
Conditions: Hypertension, Blood Pressure
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Exercise Effects on Adipose Tissue Structure and Function
NCT04812314
Recruiting
Participants will be randomized into one of two different experimental groups: 1) Exercise group and 2) No exercise (control group). Subject participation in the study will involve a series of metabolic tests before and after participants undergo a 10% weight loss program (with or without exercise training depending on group randomization). After completing this weight loss portion of the study, participants will then be required to adhere to a high calorie diet program to regain half of the wei... Read More
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
06/19/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Obesity, Metabolic Syndrome, Metabolic Disease, Insulin Resistance, Weight Loss, Weight Gain
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A Proof of Concept Pilot Study of the Addition of Venetoclax to Standard Remission Induction Chemotherapy Fludarabine or Cladrabine, Cytarabine, and Granulocyte Colony Stimulating Factor (G-CSF) (FLAG or CLAG) for Frontline Therapy of Secondary Acute Myeloid Leukemia
NCT05780879
Recruiting
The primary purpose of this study is to determine complete remission rate of a novel combination induction chemotherapy treatment based upon 20 patients with newly diagnosed secondary AML.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/18/2024
Locations: University of Michigan Rogel Cancer Center, Ann Arbor, Michigan
Conditions: Secondary Acute Myeloid Leukemia
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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
NCT04262206
Recruiting
PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and persistent disability and secondary composites including mild cognitive impairment (MCI) and cardiovascular events.
Gender:
ALL
Ages:
75 years and above
Trial Updated:
06/14/2024
Locations: VA Ann Arbor Healthcare System, Ann Arbor, Michigan +1 locations
Conditions: Cognitive Impairment, Mild, Dementia, Cardiovascular Diseases
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Burst Spinal Cord Stimulation (Burst-SCS) Study
NCT03718325
Recruiting
Recently a new form of spinal cord stimulation therapy called burst spinal cord stimulation (Burst-SCS) is available to treat chronic pain. The goal of this study is to learn more about how Burst-SCS works to reduce chronic pain. The study will examine chronic pain patients who have been deemed candidates for Burst-SCS therapy, and who have already been selected to receive a temporary externalized trial of Burst-SCS from their own doctors as part of their standard clinical care for chronic pain... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/14/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Pain, Chronic, Failed Back Surgery Syndrome
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Healing Opioid Misuse and Pain Through Engagement (HOPE) Trial
NCT05571917
Recruiting
This study is a multisite randomized clinical trial of a treatment designed to reduce pain interference while simultaneously addressing relapse prevention among individuals who have co-occurring chronic pain and Opioid Use Disorder (OUD). This study will recruit approximately 160 individuals who are currently being treated in clinics specializing in the physician management of OUD. To increase generalizability of study findings and increase internal validity of the physician management component... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/11/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Opioid Use Disorder, Chronic Pain
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Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE)
NCT04069312
Recruiting
A multi-center, randomized, 72-month, parallel- group, non-inferiority, phase III study to compare the effectiveness of roflumilast (Daliresp, 500 mcg quaque die (QD) or alternate regimen) therapy versus azithromycin (250 mg QD, 500 mg QD three times per week, or alternate regimen) to prevent hospitalization or death in a patients at high risk for COPD exacerbations.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
06/06/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Chronic Obstructive Pulmonary Disease Severe, Chronic Bronchitis
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Functional Assessment in Liver Transplantation
NCT03228290
Recruiting
This will be a prospective cohort study of patients with liver disease. Subjects will undergo geriatric assessments of frailty, functional status, and disability using functional status measures at baseline and at every clinic visit in the pre-transplant setting. Subjects will also answer questions regarding quality of life, personality, and/or cognitive function. Subjects will again undergo assessments at every clinic visit through 12 months after transplant. Then, they will be followed annuall... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/05/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: End Stage Liver Disease
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Eliminating Monitor Overuse Trial (EMO Trial)
NCT05132322
Recruiting
The purpose of this study is to identify the optimal deimplementation strategies for an overused practice: continuous pulse oximetry monitoring of children hospitalized with bronchiolitis who are not receiving supplemental oxygen.
Gender:
ALL
Ages:
2 months and above
Trial Updated:
06/03/2024
Locations: CS Mott Children's Hospital, Ann Arbor, Michigan
Conditions: Bronchiolitis Acute Viral
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One-Time DNA Study for Vasculitis
NCT01241305
Recruiting
The purpose of this study is to identify genes that increase the risk of developing vasculitis, a group of severe diseases that feature inflammation of blood vessels. Results of these studies will provide vasculitis researchers with insight into the causes of these diseases and generate new ideas for diagnostic tests and therapies, and will be of great interest to the larger communities of researchers investigating vasculitis and other autoimmune, inflammatory, and vascular diseases.
Gender:
ALL
Ages:
7 years and above
Trial Updated:
06/03/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss), Giant Cell Arteritis, Granulomatosis With Polyangiitis (Wegener's), Microscopic Polyangiitis, Polyarteritis Nodosa, Takayasu's Arteritis
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Speech Processing in Stuttering
NCT04929184
Recruiting
This research is being done to better understand stuttering, specifically how people who stutter may process and/or produce speech. Eligible participants enrolled will complete a variety of computer and speech-based tasks on up to 2 visits.
Gender:
ALL
Ages:
Between 6 years and 65 years
Trial Updated:
06/03/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Stuttering, Stuttering, Childhood, Stuttering, Adult
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Self Biophysical Profile Using a Home Ultrasound Device Proof of Concept
NCT06442358
Recruiting
The objective of this study is to assess if patients presenting for antenatal testing can complete a Bio Physical Score (BPP) with a home-use ultrasound with remote clinician guidance.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/29/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Perinatal Care
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