There are currently 962 clinical trials in Ann Arbor, Michigan looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Michigan, University of Michigan Comprehensive Cancer Center, University of Michigan Health System and C S Mott Children's Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
The Impact of an Adaptive Patient-centered Web Application on Medication Optimization in HFrEF Patients
Recruiting
The SmartHF study is a 12-week prospective randomized controlled multicenter clinical trial. This study will investigate the efficacy of an adaptive web application to facilitate guideline-directed medical therapy (GDMT) optimization in HFrEF patients. Eligible participants will be randomized to the web application intervention or control in a 1:1 manner, stratified by site. The intervention is an adaptive medication optimization web application that extracts and analyzes the EHR data with a co... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Heart Failure
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others
Recruiting
This is an observational longitudinal study to determine the natural history and genotype-phenotype correlations of disease causing mutations in Charcot Marie Tooth disease (CMT) type 1B (CMT1B), 2A (CMT2A), 4A (CMT4A), and 4C (CMT4C). The investigators will also be determine the capability of the newly developed CMT Pediatric Scale (CMT Peds scale) and the Minimal Dataset to measure impairment and perform longitudinal measurements in patients with multiple forms of CMT over a five year window
Gender:
ALL
Ages:
All
Trial Updated:
05/09/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Charcot Marie Tooth Disease
Development of Charcot Marie Tooth Disease (CMT) Pediatric Scale for Children With CMT
Recruiting
The primary goal of this project is to develop and test a Charcot Marie Tooth disease (CMT) Pediatric Scale for use in evaluation in natural history CMT study.
Gender:
ALL
Ages:
21 years and below
Trial Updated:
05/09/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Charcot Marie Tooth Disease
Fiber Supplementation in Heart Failure With Preserved Ejection Fraction (HFpEF)
Recruiting
The study team is studying how increasing dietary fiber, specifically through adding potato starch to participant's diet, may impact the species of bacteria in participant's gut microbiome. The study team also wants to understand if adding potato starch to participant's diet helps these bacteria make more short chain fatty acids, a byproduct the team thinks may benefit participant's health.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Type2diabetes, Heart Failure With Preserved Ejection Fraction
Warfarin Patient Self-management Implementation in the US Healthcare System
Recruiting
In the US, patients receiving warfarin therapy are rarely allowed to engage in patient self-management (PSM) which is less burdensome, less expensive, and safer than standard clinic-directed warfarin management. The long-term objective of our application is to improve the safety of ambulatory warfarin therapy through increasing the implementation of PSM.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Atrial Fibrillation, Venous Thromboembolism, Heart Valve Diseases
Harnessing Telemedicine to Improve Alcohol Use Disorder Outcomes in Primary Care Patients
Recruiting
The purpose of this trial is to test new programs to see if they might help people manage their health and health behaviors related to alcohol use and well-being. The program sessions focus on getting to know what's important to the participants, reviewing or setting goals, and using different skills and behaviors to better manage health. The trial will help the study team learn about ways to deliver health information in a way that is useful and interesting. This research will take place remot... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
05/03/2024
Locations: VA Ann Arbor Health Care | Veterans Affairs, Ann Arbor, Michigan +1 locations
Conditions: Substance Use Disorders, Substance Use, Substance Dependence
Enhancing Purpose and Well-Being Through a Volunteering Experience Connecting Veterans With English Language Learners
Recruiting
The goal of this study is to refine and test a strategy for engaging Veterans with symptoms of depression, anxiety, and/or PTSD (Post Traumatic Stress Disorder) as volunteers to help English language learners (ELLs) improve their speaking skills via structured conversations using videoconferencing.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: Center for Clinical Management Research (CCMR), North Campus Research Complex, Ann Arbor, Michigan
Conditions: Depression, Anxiety, Post Traumatic Stress Disorder
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease
Recruiting
The purpose of this initiative is to improve care and outcomes for infants with HLHS by expanding the NPC-QIC national registry to gather clinical care process, outcome, and developmental data on infants with HLHS between diagnosis and 12 months of age, by improving the use of standards into everyday practice across pediatric cardiology centers, and by engaging parents as partners in the process.
Gender:
ALL
Ages:
15 months and below
Trial Updated:
05/01/2024
Locations: University of Michigan C.S. Mott Children's Hospital, Ann Arbor, Michigan
Conditions: Hypoplastic Left Heart Syndrome (HLHS)
A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation
Recruiting
The purpose of this study is to compare the efficacy, safety, and tolerability of ide-cel with lenalidomide (LEN) maintenance to that of LEN maintenance alone in adult participants with Newly Diagnosed Multiple Myeloma (NDMM) who have achieved a suboptimal response post autologous stem cell transplantation (ASCT).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/01/2024
Locations: Local Institution - 0123, Ann Arbor, Michigan
Conditions: Multiple Myeloma
Connect® Myeloid Disease Registry
Recruiting
The purpose of the Connect® Myeloid disease registry is to provide unique insights into treatment decisions and treatment patterns as they relate to clinical outcomes of patients with myeloid diseases in routine clinical practice. This disease registry will also evaluate molecular and cellular markers that may provide further prognostic classification which may or may not be predictive of therapy and clinical outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: University of Michigan Health System (UMHS) - University Hospital (University of Michigan Medical Ce, Ann Arbor, Michigan
Conditions: Myelodysplastic Syndromes, Primary Myelofibrosis, Leukemia, Myeloid, Acute
Conditioning Brain Responses to Improve Thigh Muscle Function After Anterior Cruciate Ligament Reconstruction
Recruiting
The purpose of this study is to examine if thigh muscle weakness and the lack of muscle activation that accompanies ACL injury can be improved through a form of mental coaching and encouragement, known as operant conditioning.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
04/30/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Anterior Cruciate Ligament Injury
Defining the Molecular and Radiologic Phenotype of Progressive RA Interstitial Lung Disease
Recruiting
A study to identify patients with Rheumatoid Arthritis - Associated Interstitial Lung Disease (RA-ILD) that are at the highest risk for progression. The goal of the investigators is to recruit a group of patients with RA-ILD and collect information to help us understand more about disease progression. The investigators will do this using a combination of clinical, radiologic, and biologic features.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
04/29/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Rheumatoid Arthritis, Interstitial Lung Disease