The state of Michigan currently has 14 active clinical trials seeking participants for Healthy research studies. These trials are conducted in various cities, including Ann Arbor, Detroit, Grand Rapids and Kalamazoo.
How do the Neck Muscles Influence Head Acceleration During Sport-associated Impact Events in High School Athletes?
Recruiting
Sport-related concussion is a common and serious injury that can affect athletes of all ages in any sport. The purpose of this project is to study the effect of a 12-week manual resistance neck strengthening exercise program on participants' neck size and strength and how their heads and necks move during simulated sport-associated tasks. This study will help determine if greater neck strength may lower an athlete's risk of sport-related concussion. Each healthy male and female soccer athlete be... Read More
Gender:
All
Ages:
Between 13 years and 19 years
Trial Updated:
02/02/2024
Locations: Michigan Medicine, Ann Arbor, Michigan
Conditions: Sport-related Concussion, Brain Concussion, Healthy
Dose-Dependent Effect of Intranasal Insulin in Humans Using Functional Magnetic Resonance Imaging (fMRI)
Recruiting
The purpose of this trial is to study the brain response using functional MRI (fMRI) before and after varying doses of insulin given through the nose. The magnetic resonance imaging uses a very strong magnet to produce images of participant's brain. It becomes a functional MRI when the study team looks at the activity within the brain (blood flow / change in metabolism).
Gender:
All
Ages:
18 years and above
Trial Updated:
01/10/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Healthy
Targeting Large-scale Networks in Depression With Real-time fMRI (Functional Magnetic Resonance Imaging) Neurofeedback
Recruiting
The purpose of this study is to develop a technique called real time fMRI neurofeedback. This technique uses a functional MRI scanner, except that special software allows the researchers to measure activity in participants brain, using fMRI, and then give information, in the form of a feedback signal, which indicates brain activity in real time, while in the MRI scanner. The larger goal of this study is to develop ways to help people, including those with depression, better regulate brain activ... Read More
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
12/06/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Healthy Participants
Multi-modal Assessment of Gamma-aminobutyric Acid (GABA) Function in Psychosis
Recruiting
The purpose of this study is to better understand mental illness and will test the hypotheses that while viewing affective stimuli, patient groups will show increased blood oxygenation level dependent (BOLD) signal by fMRI after lorazepam. This study will enroll participants between the ages of 16 and 60, who have a psychotic illness (such as psychosis which includes conditions like schizophrenia, schizoaffective disorder, and mood disorders). The study will also enroll eligible participants wi... Read More
Gender:
All
Ages:
Between 16 years and 60 years
Trial Updated:
11/30/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Schizophrenia, Bipolar Disorder, Healthy, Psychosis, Schizophreniform Disorders, Schizo Affective Disorder, Major Depression With Psychotic Features
Fractionated 1927-nm Non Ablative Thulium Laser in Treating Post Inflammatory Hyperpigmentation
Recruiting
To study the effect of fractionated 1927-nm non ablative thulium laser in reduction of post inflammatory hyperpigmentation (PIH) using a validated and reproducible model for studying PIH. Determine if there is aa reduction in PIH in patients treated with three (3) monthly sessions of fractionated 1927-nm non ablative thulium laser Determine if there is efficacy of post-procedure clobetasol propionate 0.05% ointment in the management of PIH Determine the histological and molecular changes that o... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/20/2023
Locations: Henry Ford Medical Center, Detroit, Michigan
Conditions: Healthy
Optimizing Phototesting and Investigating Photobiology of Visible Light
Recruiting
Specific Aim 1: To determine the impact of spectral composition of the VL+UVA1 source on the associated biologic effects. Specific Aim 2: To investigate differential responses of subjects with different skin phototypes to VL+UVA1, including immediate and delayed erythema and pigmentation, and photodamage.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/23/2023
Locations: Henry Ford Medical Center, Detroit, Michigan
Conditions: Healthy
Integrated Cancer Repository for Cancer Research
Recruiting
The iCaRe2 is a multi-institutional resource created and maintained by the Fred & Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer patients, high-risk individuals, and normal controls. The distinct characteristic of the iCaRe2 is its geographical coverage, with a significant percentage of small and rural hospitals and cancer centers. The iCaRe2 advances comprehensive studies of risk factors of cancer... Read More
Gender:
All
Ages:
Between 19 years and 110 years
Trial Updated:
09/29/2023
Locations: University of Michigan Health System, Ann Arbor, Michigan
Conditions: Pancreatic Cancer, Thyroid Cancer, Lung Cancer, Esophageal Cancer, Thymus Cancer, Colon Cancer, Rectal Cancer, GIST, Anal Cancer, Bile Duct Cancer, Duodenal Cancer, Gallbladder Cancer, Gastric Cancer, Liver Cancer, Small Intestine Cancer, Peritoneal Surface Malignancies, Familial Adenomatous Polyposis, Lynch Syndrome, Bladder Cancer, Kidney Cancer, Penile Cancer, Prostate Cancer, Testicular Cancer, Ureter Cancer, Urethral Cancer, Hypopharyngeal Cancer, Laryngeal Cancer, Lip Cancer, Oral Cavity Cancer, Nasopharyngeal Cancer, Oropharyngeal Cancer, Paranasal Sinus Cancer, Nasal Cavity Cancer, Salivary Gland Cancer, Skin Cancer, CNS Tumor, CNS Cancer, Mesothelioma, Breast Cancer, Leukemia, Melanoma, Sarcoma, Unknown Primary Tumor, Multiple Myeloma, Ovarian Cancer, Endometrial Cancer, Vaginal Cancer, Neuroendocrine Tumors, Plasma Cell Dyscrasia, Healthy Control
Eat My ABCs Project
Recruiting
Evaluate the effects of the "Eat My ABCs" program on improving Head Start preschoolers' eating behavior and anthropometric properties (BMI, percent body fat).
Gender:
All
Ages:
Between 3 years and 5 years
Trial Updated:
08/25/2023
Locations: Northeast Michigan Community Service Agency, Alpena, Michigan +1 locations
Conditions: Nutrition, Healthy, Obesity, Childhood
Brain State-dependent Stimulation to Improve Movement
Recruiting
Repetitive transcranial magnetic stimulation (rTMS) is a powerful tool to non-invasively modulate brain circuits, brain plasticity, and behavior. This proposal will test the hypothesis that controlling behavioral state during focal multi-day rTMS of a brain region involved in grasping movements will enhance the functional specificity of the neuromodulation action among distributed brain regions involved in voluntary motor control and concomitantly improve manual dexterity. Results from this stud... Read More
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
08/18/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Healthy
Identification of Biomarkers for Stress Vulnerability and Resilience
Recruiting
The purpose of this research study is to understand the biological mechanisms of stress vulnerability (being susceptible to stress) and stress resilience (being able to recover readily from stress), obtain biomarkers (a biological indicator) for stress resilience and to devise strategies for prevention and treatment of stress-related disorders.
Gender:
All
Ages:
Between 18 years and 22 years
Trial Updated:
07/28/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Healthy
Effectiveness of Aquamin® in Mitigating Halitosis
Recruiting
The purpose of this study is to assess whether Aquamin®, a multi-mineral natural product from red marine algae, can help reduce halitosis when taken for 90 days.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
07/25/2023
Locations: University of Michigan School of Dentistry, Ann Arbor, Michigan
Conditions: Healthy, Halitosis
GI Permeability Change in Response to Aquamin®
Recruiting
This trial is being completed to learn about how Aquamin® affects gastrointestinal permeability, or the control of material passing from inside the gastrointestinal tract through the gut wall into the rest of the body, in people with ulcerative colitis (UC), Irritable Bowel Syndrome with diarrhea (IBS-D), and in healthy individuals.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/02/2023
Locations: University of Michigan Hospital, Ann Arbor, Michigan
Conditions: Healthy, Ulcerative Colitis, Irritable Bowel Syndrome With Diarrhea