There are currently 3 active clinical trials seeking participants for Epidermolysis Bullosa research studies. The states with the highest number of trials for Epidermolysis Bullosa participants are California, Illinois, Minnesota and Texas.
Targeting Collagen VII Antibodies With IV IgG in Dystrophic Epidermolysis Bullosa
Recruiting
The study objective is to see if IV IgG treatment in Recessive Dystrophic Epidermolysis Bullosa (RDEB) skin in conjunction with VYJUVEK treatment improves wound healing and affects the levels of C7 and HSV-1 antibody levels in serum. Fewer wounds, more rapidly healing wounds, and decreased C7 and HSV-1 antibodies could improve quality of life.
Gender:
ALL
Ages:
6 years and above
Trial Updated:
07/31/2025
Locations: Stanford University, Redwood City, California
Conditions: Epidermolysis Bullosa, Epidermolysis Bullosa Acquisita, Dystrophic Epidermolysis Bullosa, Recessive Dystrophic Epidermolysis Bullosa
Computational Drug Repurposing for All EBS Cases
Recruiting
The study will compare gene expression differences between blistered and non-blistered skin from individuals with all subtypes of EB, as well as normal skin from non-EB subjects. State of the art computational analysis will be performed to help identify new drugs that might help all EB wound healing and reduce pain. Researchers will focus on drugs that have already been approved for treatment of other dermatologic or non-dermatologic diseases, and therefore be repurposed for treatment of EB. Dru... Read More
Gender:
ALL
Ages:
0 years and above
Trial Updated:
02/11/2024
Locations: Pediatric Dermatology Clinic at Stanford Children's Hospital, Palo Alto, California
Conditions: Epidermolysis Bullosa Simplex, Healthy, Genetic Skin Disease, Epidermolysis Bullosa, Epidermolysis Bullosa, Junctional, Epidermolysis Bullosa Dystrophica
Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Epidermolysis Bullosa (Phase III)
Recruiting
The aim of this clinical trial is to investigate the safety and efficacy of allo-APZ2-OTS administered intravenously to subjects with recessive dystrophic epidermolysis bullosa (RDEB) compared to placebo.
Gender:
ALL
Ages:
6 months and above
Trial Updated:
10/27/2023
Locations: Masonic Cancer Center and Medical Center Minneapolis, Minneapolis, Minnesota
Conditions: Epidermolysis Bullosa