The state of Minnesota currently has 32 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including Minneapolis, Rochester, Saint Paul and Duluth.
Telerehabilitation for TMD
Recruiting
This study will compare after physical therapy for Temporomandibular Disorders (TMD) performed either in-person or virtually using telerehabilitation. Comparing diagnostic reliability and quality-of-life outcomes in each group will determine (based on a 10% margin) whether delivering physical therapy via telerehabilitation is as good as standard in-person care for these individuals. Long term outcomes including patient satisfaction, cost-effectiveness analysis, and functional status will describ... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
04/09/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Temporomandibular Disorder, TMJ Disc Displacement With Reduction, TMJ Disc Displacement Without Reduction, Masticatory Myofascial Pain, TMJ Arthralgia, TMD Headache
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Recruiting
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK of understudied drugs currently being administered to children per SOC as prescribed by their treating provider.
Gender:
All
Ages:
Between 0 years and 20 years
Trial Updated:
03/29/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Hemophilia, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma
Recruiting
This phase II trial studies how well low-dose radiotherapy works in treating bone pain in patients with multiple myeloma that has spread to the bone. Radiation therapy uses high energy x-rays, gamma rays, neutrons, protons, or other sources to kill tumor cells and shrink tumors. Low-dose radiotherapy may be more convenient for patients and their families, may not interfere as much with the timing of chemotherapy, and may have less chance for short term or long-term side effects from the radiatio... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/26/2024
Locations: University of Minnesota - Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Bone Pain, Metastatic Malignant Neoplasm in the Bone, Plasma Cell Myeloma
Transdiagnostic Cognitive Biomarkers
Recruiting
The overall objective of this study is to determine the feasibility of identifying transdiagnostic biomarkers of cognitive function mediated by neuromodulation of the dorsolateral prefrontal cortex that are translatable across disease groups in order to more accurately phenotype clusters of cognitive dysfunction. Completing behavioral paradigms with electrophysiology and TMS is a challenging frontier. This study focuses on the feasibility of such an endeavor for those with chronic pain or depres... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/13/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Pain, Depression
LLLT to Reduce Low Back Pain
Recruiting
The purpose of this research study is to gather information on the effectiveness of the Trident low-level laser therapy (LLLT) in combination with clinical patient education manuals to reduce lower back pain.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Low Back Pain
iFuse TORQ for the Treatment of Sacroiliac Joint Dysfunction
Recruiting
STACI is a prospective, multicenter, study of SIJ fusion using the iFuse TORQ implant system.
Gender:
All
Ages:
21 years and above
Trial Updated:
03/05/2024
Locations: iSpine, Maple Grove, Minnesota
Conditions: Sacroiliac Joint Dysfunction, Sacroiliac; Fusion, Sacroiliac Disorder, Sacroiliac Joint Pain
Graded Motor Imagery for Women at Risk for Developing Type I CRPS Following Closed Treatment of Distal Radius Fractures
Recruiting
Nearly 2 out of 10 women will sustain a distal forearm fracture throughout their lifespan.Recent longitudinal studies illustrate that as many as 1/3 of all persons who undergo closed reduction and casting for distal radius fractures (DRF) go on to develop type 1 complex regional pain syndrome (CRPS). Graded motor imagery (i.e., motor imagery and mirror therapy), a movement representation technique, is strongly supported in the literature as a treatment of CRPS and has recently been suggested as... Read More
Gender:
Female
Ages:
55 years and above
Trial Updated:
02/16/2024
Locations: University of Minnesota Program in Occupational Therapy, Minneapolis, Minnesota
Conditions: Musculoskeletal Pain, Fractures, Closed, Distal Radius Fracture, Complex Regional Pain Syndromes
Brivaracetam to Reduce Neuropathic Pain in Chronic SCI: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Recruiting
Spinal cord injury (SCI) is associated with severe neuropathic pain that is often refractory to pharmacological intervention. Preliminary data suggest brivaracetam is a mechanism-based pharmacological intervention for neuropathic pain in SCI. Based on this and other reports in the literature, SCI-related neuropathic pain is hypothesized to occur largely because of upregulation of synaptic vesicle protein 2A (SV2A) within the substantia gelatinosa of the injured spinal cord. Furthermore, compared... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/16/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Spinal Cord Injuries, Neuropathic Pain
Treating Negative Affect in Low Back Pain Patients
Recruiting
This study will examine how the use of antidepressant, physical therapy, and combination of both affects pain, function, and depression outcomes in chronic low back pain patients.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
02/16/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Chronic Low Back Pain, Negative Affectivity
Improving Spinal Cord Stimulation With ECAPS
Recruiting
The purpose of this study will be to investigate the optimization of spinal cord stimulation with ECAPs in patients with spinal cord implants.
Gender:
All
Ages:
22 years and above
Trial Updated:
01/24/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Chronic Pain
Chronic Postsurgical Pain
Recruiting
The study purpose is to document the typical trajectory of perioperative pain experience in Cerebral Palsy (CP) and to identify important predictive factors for the development of chronic postsurgical pain. The main aims of the investigators are to: Quantify the trajectory of pain and opioid use in the context of orthopedic surgery in children with CP. Identify predictors for CPSP in children with CP and develop an applicable risk index. Examine relationships between perioperative pain severity... Read More
Gender:
All
Ages:
Between 5 years and 17 years
Trial Updated:
01/12/2024
Locations: Gillette Children's Specialty Healthcare, Saint Paul, Minnesota
Conditions: Cerebral Palsy, Chronic Post Surgical Pain
Long-Term Real-World Outcomes Study on Patients Implanted With a Neurostimulator
Recruiting
The REALITY study is a prospective, post-market, non-randomized, multi-center, single-arm, open-label study intended to collect short- and long-term safety and effectiveness data on various populations implanted with Abbott's neurostimulation systems.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/08/2024
Locations: Nura, Edina, Minnesota +2 locations
Conditions: Chronic Pain