The state of Minnesota currently has 32 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including Minneapolis, Rochester, Saint Paul and Duluth.
Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)
Recruiting
The main objective of the study is to evaluate the safety, performance and clinical benefits of the Persona implant and its instrumentation in primary total knee arthroplasty
Gender:
All
Ages:
18 years and above
Trial Updated:
06/18/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Knee Pain Chronic, Osteoarthritis, Knee, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee, Avascular Necrosis
Radiofrequency (RF) Ablation Prospective Outcomes Study
Recruiting
The objective of this study is to compile real-world outcomes of Boston Scientific commercially approved radiofrequency (RF) ablation systems in the treatment of patients diagnosed with pain and in use for central nervous system (CNS) applications for other disorders.
Gender:
All
Ages:
0 years and above
Trial Updated:
06/11/2024
Locations: Twin Cities Pain Clinic and Surgery Center, Edina, Minnesota
Conditions: Pain, Chronic
Patient Retrospective Outcomes (PRO)
Recruiting
This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/11/2024
Locations: Twin Cities Pain Clinic & Surgery Center, Edina, Minnesota
Conditions: Chronic Pain
Exparel Injection for Postoperative Orbital Pain
Recruiting
After surgery to remove the eye, either by enucleation or evisceration, patients have variable levels of pain for several postoperative days. Some patients have almost no discomfort while others require significant amounts of oral narcotics and report pain of 10 out of 10 on a numerical rating scale. The current operative standard is to infiltrate the eye socket with 0.5% bupivacaine during surgery leading to several hours of postoperative analgesia. In 2011, Pacira Pharmaceuticals released a bu... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/11/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Pain, Postoperative
Study of V117957 in Interstitial Cystitis/Bladder Pain Syndrome
Recruiting
The purpose of this study is to evaluate the safety, tolerability and efficacy of V117957 in subjects with interstitial cystitis/bladder pain syndrome, compared to placebo.
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/31/2024
Locations: CentraCare - Urology Clinic, Sartell, Minnesota
Conditions: Interstitial Cystitis/Bladder Pain Syndrome
Zimmer Biomet Shoulder Arthroplasty PMCF
Recruiting
The objectives of this study are to confirm the safety, performance, and clinical benefits of Zimmer Biomet Shoulder Arthroplasty Systems and its instrumentation in primary or revision shoulder arthroplasty. These objectives will be assessed using standard scoring systems, radiographic evidence, and adverse event records. Safety of the system will be assessed by monitoring the frequency an incidence of adverse events.
Gender:
All
Ages:
20 years and above
Trial Updated:
05/09/2024
Locations: TRIA Orthopaedic Center Research Institute, Bloomington, Minnesota
Conditions: Shoulder Fractures, Shoulder Arthritis, Shoulder Osteoarthritis, Shoulder Deformity, Shoulder Injuries, Shoulder Pain
Normalizing Cervical Intersegmental Kinematics With Spinal Manipulative Therapy
Recruiting
The broad long-term objective is to develop an objective biomarker for spinal health based on aberrant or abnormal movement patterns during functional activities to better target spinal manipulation therapy (SMT) and other conservative treatments. The central hypotheses are a) that aberrant spinal motions and their location (area and level) are indicative of underlying spinal dysfunction, and b) that quantified 3D cervical spine intersegmental and global motion patterns during functional tasks c... Read More
Gender:
All
Ages:
Between 18 years and 39 years
Trial Updated:
05/08/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Neck Pain
A Study of Intrathecal Hydromorphone for Pediatric Idiopathic Scoliosis Repair
Recruiting
The purpose of this study is to identify a dose of intrathecal hydromorphone (opioid pain medicine) that optimizes pain control but minimizes side effects historically seen with this class of pain medications.
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
05/08/2024
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Pain Control
Trial Readiness and Endpoint Assessment in LGMD R1
Recruiting
This is a 24-month, observational study of 100 participants with Limb Girdle Muscular Dystrophy type R1, also known as CAPN3.
Gender:
All
Ages:
Between 12 years and 50 years
Trial Updated:
05/06/2024
Locations: University of Minnesota, Department of Neurology, Minneapolis, Minnesota
Conditions: Calpain-3 Deficiency Limb Girdle Muscular Dystrophy Type 2A, Limb Girdle Muscular Dystrophy, Limb Girdle Muscular Dystrophy Type R1, LGMD2A
Study to Evaluate Neuromodulation Subject Experience With Contemporary Spinal Cord Stimulation (SCS) Modalities for Chronic Pain
Recruiting
Medtronic, Inc. is sponsoring the SENSE SCS clinical study, a prospective, multi-center, post-market, non-randomized, observational study with a hybrid decentralized model of execution, utilizing a mobile application for the collection of patient reported outcomes (PROs). The purpose of the study is to evaluate workflow of a mobile application for collection of PROs and to gather data on patient experience with spinal cord stimulation therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/24/2024
Locations: Twin Cities Pain Clinic, Edina, Minnesota
Conditions: Pain, Intractable, Pain, Chronic
Brain Connectivity Patterns in Chronic Temporomandibular Joint Disorders
Recruiting
This study addresses the timely problem of painful temporomandibular disorders (TMD), the most common cause of orofacial pain second only to tooth pain. Findings from previous studies suggest that dysregulation of connectivity within specific brain circuits is part of chronic pain pathophysiology. This study will identify connectivity patterns within those brain circuits as potential signatures for pain- related disability in chronic TMD pain participants. New knowledge regarding these brain con... Read More
Gender:
Female
Ages:
Between 18 years and 65 years
Trial Updated:
04/17/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Chronic Pain, Temporomandibular Joint Disorders, Temporomandibular Joint Pain
Home-based Rehabilitation Intervention for Phantom Limb Pain in Veterans With Lower Limb Amputations
Recruiting
Nearly 60-85% of Veterans with amputations experience pain at the location of the amputated limb called phantom limb pain (PLP). PLP is a major problem and can have a profound impact on Veteran's daily function and ability to fully participate in life. Although several rehabilitation interventions are promising, advances in novel rehabilitation interventions are limited. The objective of this project is to refine a mobile app for graded motor imagery in 12 Veterans with amputations and test the... Read More
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
04/15/2024
Locations: Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis, Minnesota
Conditions: Phantom Limb Pain