There are currently 901 clinical trials in Minneapolis, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Minnesota, Hennepin County Medical Center, Abbott Northwestern Hospital and University of Minnesota/Masonic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Allo HSCT Using RIC and PTCy for Hematological Diseases
NCT05805605
Recruiting
This is a Phase II study following subjects proceeding with our Institutional non-myeloablative cyclophosphamide/ fludarabine/total body irradiation (TBI) preparative regimen followed by a related, unrelated, or partially matched family donor stem cell infusion using post-transplant cyclophosphamide (PTCy), sirolimus and MMF GVHD prophylaxis.
Gender:
All
Ages:
75 years and below
Trial Updated:
05/06/2024
Locations: Masonic Cancer Center at University of Minnesota, Minneapolis, Minnesota
Conditions: Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Biphenotypic Acute Leukemia, Undifferentiated Leukemia, Prolymphocytic Leukemia, Chronic Myelogenous Leukemia, Plasma Cell Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Myelodysplastic Syndrome With Excess Blasts-1, Burkitt Lymphoma, Relapsed T-Cell Lymphoma, Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Marginal Zone Lymphoma, Follicular Lymphoma, Myeloproliferative Neoplasm, Myelofibrosis
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Trial Readiness and Endpoint Assessment in LGMD R1
NCT05618080
Recruiting
This is a 24-month, observational study of 100 participants with Limb Girdle Muscular Dystrophy type R1, also known as CAPN3.
Gender:
All
Ages:
Between 12 years and 50 years
Trial Updated:
05/06/2024
Locations: University of Minnesota, Department of Neurology, Minneapolis, Minnesota
Conditions: Calpain-3 Deficiency Limb Girdle Muscular Dystrophy Type 2A, Limb Girdle Muscular Dystrophy, Limb Girdle Muscular Dystrophy Type R1, LGMD2A
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Adrenoleukodystrophy National Registry Study
NCT03789721
Recruiting
The aim of this registry to understand the natural history and disease progression in ALD and potentially develop bio-markers using the biospecimens collected using this registry.
Gender:
All
Ages:
All
Trial Updated:
05/06/2024
Locations: Masonic Cancer Center at University of Minnesota, Minneapolis, Minnesota
Conditions: ALD (Adrenoleukodystrophy), Adrenoleukodystrophy, Cerebral Adrenoleukodystrophy
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Multi-level Predictors of Structural Racism and Discrimination and Associations With Health and Well-being Across the Life Course in Diverse Families
NCT05744973
Recruiting
Minoritized populations face mutually reinforcing levels of structural disadvantage that contribute to poor health. Despite recognition that social and economic stratification, environmental conditions, and policy are critical determinants of health disparities, there has been limited effort in expanding interventions beyond the individual level to disrupt systemic causes of health. This is in part due to the challenges of describing how racism and discrimination have become systematized over ti... Read More
Gender:
All
Ages:
Between 8 years and 18 years
Trial Updated:
05/06/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Racially/Ethnically Diverse Families From Urban Settings
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Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects With Non-Ischemic NYHA Class III Heart Failure
NCT05598333
Recruiting
This is a Phase 2 adaptive, double-blinded, placebo-controlled, randomized, multi-center trial study to evaluate the safety and efficacy of a single dose of AB-1002, administered via antegrade intracoronary artery infusion, in males and females age >18 years with non-ischemic cardiomyopathy and NYHA Class III symptoms of HF. Subjects will be randomized into one of three treatment groups in a 1:1:1
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: Minneapolis Heart Institute, Minneapolis, Minnesota
Conditions: Congestive Heart Failure
Register for Updates
Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment
NCT05561387
Recruiting
This phase III trial compares three-drug induction regimens followed by double-or single-drug maintenance therapy for the treatment of newly diagnosed multiple myeloma in patients who are not receiving a stem cell transplant and are considered frail or intermediate-fit based on age, comorbidities, and functional status. Treatment for multiple myeloma includes initial treatment (induction) which is the first treatment a patient receives for cancer followed by ongoing treatment (maintenance) which... Read More
Gender:
All
Ages:
All
Trial Updated:
05/03/2024
Locations: Abbott-Northwestern Hospital, Minneapolis, Minnesota +2 locations
Conditions: Plasma Cell Myeloma
Register for Updates
Financial Navigation Program to Improve Understanding and Management of Financial Aspects of Cancer Care for Patients and Their Spouses
NCT04960787
Recruiting
This clinical trial examines a financial navigation program in helping patients (and their spouses or partner caregivers, if participating) understand and better manage the financial aspects of cancer care. Cancer patients and their spouse/partner caregivers may be at high risk for financial problems because of the cost of cancer treatment. A financial navigator is a person or team who works with patients and their families to help them reduce stress or hardship related to the cost of cancer tre... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/02/2024
Locations: Abbott-Northwestern Hospital, Minneapolis, Minnesota +1 locations
Conditions: Hematopoietic and Lymphoid Cell Neoplasm, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm
Register for Updates
Diabetes RElated to Acute Pancreatitis and Its Mechanisms
NCT05197920
Recruiting
The overriding objective of DREAM is to conduct a prospective longitudinal (36 months) observational clinical study to investigate the incidence, etiology, and pathophysiology of diabetes mellitus (DM) following acute pancreatitis (AP).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/02/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Acute Pancreatitis
Register for Updates
Health Outcomes of Parents With Cystic Fibrosis
NCT05829694
Recruiting
This project will determine the health impact of parenthood on people with cystic fibrosis (CF). The study team will use retrospective data to provide relatively immediate evidence on parenthood's effect on pulmonary health.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/02/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Cystic Fibrosis, Parenthood Status
Register for Updates
SGLT2 Inhibitors After Acute Kidney Injury With Indications Pilot
NCT06124924
Recruiting
SGLT2i have been shown to reduce risk for mortality, progression of chronic kidney disease, and cardiovascular outcomes in these populations. Yet, because SGLT2i can have an acute hemodynamic effect on kidney function, in clinical practice providers are wary of providing these medications to patients who have established indications but recently had acute kidney injury (AKI). This is a pilot interventional study to collect process-data (measures of recruitment and measures of adherence) that ca... Read More
Gender:
All
Ages:
Between 40 years and 75 years
Trial Updated:
05/02/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Acute Kidney Injury
Register for Updates
Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN)
NCT06291376
Recruiting
The primary objective of this study to evaluate the efficacy of ravulizumab compared with placebo to reduce proteinuria and slow the rate of eGFR decline in adult participants with IgAN who are at risk of disease progression.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/02/2024
Locations: Research Site, Minneapolis, Minnesota +1 locations
Conditions: Immunoglobulin A Nephropathy, IgAN
Register for Updates
Intermittent Pneumatic Compression With and Without Exercise to Improve Functioning in Peripheral Artery Disease
NCT03871075
Recruiting
The INTERCEDE randomized trial will establish whether six-months of intermittent pneumatic compression combined with walking exercise improves walking endurance at six-month follow-up, compared to walking exercise + sham compression therapy, in people with lower extremity peripheral artery disease (PAD). The INTERCEDE trial will also determine whether intermittent pneumatic compression therapy improves walking endurance at 6-month follow-up, compared to a sham compression therapy. The trial will... Read More
Gender:
All
Ages:
55 years and above
Trial Updated:
05/02/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Peripheral Artery Disease
Register for Updates