There are currently 901 clinical trials in Minneapolis, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Minnesota, Hennepin County Medical Center, Abbott Northwestern Hospital and University of Minnesota/Masonic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Clinical and Basic Investigations Into Congenital Disorders of Glycosylation
NCT04199000
Recruiting
The purpose of this research is to study the natural history of congenital disorders of glycosylation and its causes and treatments.
Gender:
All
Ages:
All
Trial Updated:
04/24/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Congenital Disorders of Glycosylation
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A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors
NCT05812027
Recruiting
TScan Therapeutics is developing cellular therapies across multiple solid tumors in which autologous participant-derived T cells are engineered to express a T cell receptor that recognizes cancer-associated antigens presented on specific Human Leukocyte Antigen (HLA) molecules. The purpose of this screening study is to collect samples to conduct HLA genotyping, HLA Loss of Heterozygosity (LOH) and expression of Tumor-associated Antigens (TAA) testing. These results will be used to determine if s... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/24/2024
Locations: University of Minnesota, Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Head and Neck Cancer, Cervical Cancer, Non Small Cell Lung Cancer, Melanoma, Ovarian Cancer, HPV16 Related Cancers
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Study of Intravenous Amisulpride for Prophylaxis of Post-operative Nausea and Vomiting (PONV) in Pediatric Patients
NCT05546359
Recruiting
Randomized, double-blind, pediatric trial of amisulpride for prophylaxis of post operative nausea and vomiting
Gender:
All
Ages:
Between 2 months and 17 years
Trial Updated:
04/24/2024
Locations: University of Minnesota Masonic Children's Hospital, Minneapolis, Minnesota
Conditions: Nausea and Vomiting, Postoperative
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TRE in Type 2 Diabetes (See Food Study 3)
NCT05290246
Recruiting
Hyperglycemia in patients with Type 2 Diabetes Mellitus is initially treated with metformin coupled with intentional caloric restriction, which is difficult to sustain due to multiple barriers, including acquiring the necessary knowledge, teaching the intervention, cost of delivery and potential burden on quality of life. In contrast to intentionally restricting calories, time restricted eating (TRE), presents a simplified view of eating focused on restricting the eating window, which allows ad... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/23/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Type2Diabetes
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MAGNETIC RESONANCE SPECTROSCOPY BIOMARKERS IN TYPE 3 GAUCHER DISEASE (GD3)
NCT05586243
Recruiting
Recent studies have has shown that magnetic resonance spectroscopy (MRS) can provide validated neuronal markers in patients with Type 1 GD (GD1) who are on stable therapy. However, alterations in neurometabolites in adult patients with GD3, who have established neurological involvement, are not well understood. The goal of this study is to characterize neurometabolite profiles in adult patients with GD3 using MRS to identify novel biomarkers that can demonstrate treatment response. Additionally,... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/23/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Gaucher Disease, Type 3
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MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
NCT03072927
Recruiting
This prospective longitudinal study will compare incidence rates of Medicare beneficiary surgical and minimally invasive intervention post index procedure, as well as harms associated with the MILD procedure, at 24 months post-treatment with MILD, tested against a control group of similar patients that have had a comparable procedure. This study will start with patients treated with a study procedure having an index date on or after January 1, 2017, and enrollment will continue until stopped by... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: Nura Precision Pain Management - Edina Clinic, Minneapolis, Minnesota +1 locations
Conditions: Lumbar Spinal Stenosis
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Trigeminal Neuralgia Electrophysiology
NCT05269472
Recruiting
The study intervention is to perform standard somatosensory evoked responses limited to the face during rhizotomy procedures of the gasserian ganglion (trigeminal ganglion) for the treatment of trigeminal neuralgia. The evoked responses will be measured at two locations before and after the clinical rhizotomy including: the standard contralateral scalp (EEG) and at the gasserian ganglion through an FDA-approved recording electrode.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Trigeminal Neuralgia
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Extracellular Vesicles as Potential Biomarkers and Therapeutic Target in Gaucher Disease
NCT05843552
Recruiting
This is an observational study intended to generate preliminary data to understand how lysosomal dysfunction can affect the biogenesis of extracellular vesicles, its content and function. The primary objective of the proposed project is to decipher how extracellular vesicle (EV) biogenesis and its role in intercellular communication can be impaired as a consequence of defects in lysosomal function. Collectively these defects in EV biogenesis and function can contribute to the neuroinflammation o... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/23/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Gaucher Disease
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Type 1 Diabetes Extension Study
NCT02734277
Recruiting
This is a multi-center, prospective, non-interventional study that focuses on the long- term effects following participation in selected ITN new-onset Type1 Diabetes Mellitus studies with immunomodulatory agents (T1DM, T1D). This observational study will: follow participants to determine how long they continue to produce insulin, and will also assess how changes in the immune system over time relate to the ability to produce insulin. This information could help design better therapies for typ... Read More
Gender:
All
Ages:
Between 8 years and 35 years
Trial Updated:
04/23/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Type 1 Diabetes Mellitus, T1DM, T1D
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Hemodynamic Assessment of the Right Ventricle Using Pressure-volume Loop Catheter and Pulmonary Artery Catheter in Patients Undergoing Left Ventricular Assist Device Placement
NCT04478890
Recruiting
This study will include the placement of a pressure volume (PV) loop catheter in the right atrium of patients undergoing left ventricular assist device (LVAD) placement and measure relevant PV loop data. Transesophageal echocardiography (TEE) and pulmonary artery (PA) catheter parameters as comparators to the PV loop will be recorded.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Right Ventricular Dysfunction
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MRI Technical Development and Applications in Kidney Disease
NCT02421497
Recruiting
Magnetic resonance imaging (MRI), as a non-invasive and non-contrast enhanced technique, has the potential to improve patient health care and management. The overall objective of proposed project is to: develop, customize, and optimize anatomic and functional MRI methods, explore the use of MRI methods to study CKD and evaluate post-transplant kidneys, and investigate the potential of MRI in the diagnosis, prognosis, and monitoring of the progression of renal dysfunction. In addition to direct... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
04/23/2024
Locations: Center for Magnetic Resonance Research, Minneapolis, Minnesota
Conditions: Chronic Kidney Diseases, Kidney Transplantation, Dialysis, Cognition Disorders
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Epidural Stimulation After Neurologic Damage
NCT03026816
Recruiting
This study will evaluate a method to optimize parameter settings in epidural spinal cord stimulation used to recover lower extremity volitional movement. The study will also characterize improvement in autonomic function (such as blood pressure control) and other functions related to spinal cord injury.
Gender:
All
Ages:
22 years and above
Trial Updated:
04/23/2024
Locations: Hennepin County Medical Center, Minneapolis, Minnesota
Conditions: Spinal Cord Injuries, Paraplegia, Complete
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