There are currently 901 clinical trials in Minneapolis, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Minnesota, Hennepin County Medical Center, Abbott Northwestern Hospital and University of Minnesota/Masonic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Study to Evaluate the Safety, Reactogenicity, and Effectiveness of mRNA-1273.214 SARS-CoV-2 (COVID-19) Vaccine in Infants
NCT05584202
Recruiting
The study will evaluate the safety, tolerability, reactogenicity, and effectiveness of mRNA-1273.214 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine in infants aged 12 weeks to < 6 months.
Gender:
All
Ages:
Between 2 months and 6 months
Trial Updated:
03/12/2024
Locations: Clinical Research Institute, Inc, Minneapolis, Minnesota
Conditions: SARS-CoV-2
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Study to Evaluate the Safety and Tolerability of Ferric Citrate in Children With Hyperphosphatemia Related to Chronic Kidney Disease
NCT04523727
Recruiting
This study will be conducted to assess the safety and tolerability of ferric citrate in pediatric participants with hyperphosphatemia related to chronic kidney disease (CKD).
Gender:
All
Ages:
Between 6 years and 16 years
Trial Updated:
03/12/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Hyperphosphatemia Related to Chronic Kidney Disease
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Multimodal Profiling of Response to Pediatric Comprehensive Behavioral Intervention for Tics
NCT06194305
Recruiting
Tourette Syndrome and Persistent Motor/Vocal Tic Disorder affect 1-3% of youth and can be associated with impaired functioning, emotional and behavioral problems, physical pain, diminished quality of life, and peer victimization. Chronic tics are the primary symptom. Comprehensive Behavioral Intervention for Tics (CBIT) is a manualized treatment focused on tic management skills. During the core CBIT procedure, competing response training, patients learn to inhibit tics by engaging in a competing... Read More
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
03/12/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Tourette Syndrome, Persistent Tic Disorder
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A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
NCT03887715
Recruiting
Objectives of this study are to determine whether active VNS Therapy treatment is superior to a no stimulation control in producing a reduction in baseline depressive symptom severity, based on multiple depression scale assessment tools at 12 months from randomization.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Treatment Resistant Depression
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LOWER: Lomitapide Observational Worldwide Evaluation Registry
NCT02135705
Recruiting
This global product exposure registry is a multicentre, long-term, prospective, observational cohort study (exposure registry), designed to evaluate the long term safety and effectiveness of lomitapide.
Gender:
All
Ages:
All
Trial Updated:
03/11/2024
Locations: Minneapolis Heart Institute Foundation, Minneapolis, Minnesota
Conditions: Homozygous Familial Hypercholesterolemia
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Evaluation of the PrevisEA Device for Predicting Gastrointestinal Impairment
NCT04880473
Recruiting
PrevisEA is a noninvasive, disposable device that uses audio spectral analysis of sounds produced by the gastrointestinal tract to predict gastrointestinal impairment (GII). GII is most commonly associated with postoperative ileus (POI), but could be the result of other causes, such as early postoperative bowel obstruction. GII is defined as failure of successful early oral re-feeding in a subject undergoing major abdominal surgery. For subjects who are allowed to resume a diet during the first... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
03/11/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Gastrointestinal Complication
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A Phase II Trial of Poly-ICLC for Low-Grade Gliomas
NCT04544007
Recruiting
This is a phase II, prospective, longitudinal, multi-center trial of poly-ICLC (Hiltonol ®) treatment for progressive low-grade gliomas in pediatric patients with NF1. The primary objective is to evaluate the efficacy of poly-ICLC in pediatric NF1 patients with progressive low-grade glioma (LGG) as measured by objective tumor response rate (CR+PR) within the first 48 weeks (12 cycles) of therapy. There will also be secondary and exploratory objectives listed in the detailed description below.
Gender:
All
Ages:
22 years and below
Trial Updated:
03/08/2024
Locations: Mayo Clinic (Site 908), Minneapolis, Minnesota
Conditions: NF1, Low-grade Glioma
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A Natural History Study of the Gangliosidoses
NCT00668187
Recruiting
Hypothesis: To characterize and describe disease progression and heterogeneity of the gangliosidosis diseases. This research study seeks to develop a quantitative method to delineate disease progression for the gangliosidosis diseases (Tay-Sachs disease, Sandhoff disease, and GM1 gangliosidosis) in order to better understand the natural history and heterogeneity of these diseases. Such a quantitative method will also be essential for evaluating any treatments that may become available in the fu... Read More
Gender:
All
Ages:
All
Trial Updated:
03/08/2024
Locations: University of Minnesota - Pediatric Genetics and Metabolism, Minneapolis, Minnesota
Conditions: Tay-Sachs Disease, Sandhoff Disease, Late Onset Tay-Sachs Disease, GM1 Gangliosidosis, GM2 Gangliosidosis
Register for Updates
Effect of Airway Video Library on Intubation in Novices
NCT04956796
Recruiting
Endotracheal intubation requires significant training and expertise. This experience can be quite stressful for novice users. To accelerate the learning curve of newly enrolled trainees to assess and secure airway, the investigators propose supplementing current training techniques with access to an airway video library consisting of real- life clinical videos of airway and endotracheal intubations.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/08/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Anesthesia, Anesthesia Intubation Complication
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Modified VR-CAP and Acalabrutinib as First Line Therapy for the Treatment of Transplant-Eligible Patients With Mantle Cell Lymphoma
NCT04626791
Recruiting
This phase II trial investigates how well modified VR-CAP (bortezomib, rituximab, cyclophosphamide, doxorubicin hydrochloride, prednisone, and cytarabine hydrochloride) and acalabrutinib as first line therapy work in treating transplant-eligible patients with mantle cell lymphoma. Modified VR-CAP is a combination of drugs used as standard first line treatment for mantle cell lymphoma. Chemotherapy drugs, such as bortezomib, cyclophosphamide, doxorubicin hydrochloride, and cytarabine hydrochlorid... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
03/08/2024
Locations: Metropolitan-Mount Sinai Medical Center, Minneapolis, Minnesota
Conditions: Mantle Cell Lymphoma
Register for Updates
Phase-dependent Evaluation of Motor Cortex Excitability With TMS in Stroke
NCT04968743
Recruiting
The purpose of this study is to investigate the effects of transcranial magnetic stimulation (TMS) on motor cortex excitability in individuals who have suffered stroke and to study the influence of the phase of the oscillatory rhythm (mu frequency) on motor excitability in stroke individuals.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/08/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Stroke
Register for Updates
Visual Remapping to Aid Reading With Field Loss
NCT03848663
Recruiting
Reading performance in patients with Central Vision Loss and age matched controls with artificial scotomas will be measured with and without different kinds of remapping of missing text to different parts of the visual field.
Gender:
All
Ages:
16 years and above
Trial Updated:
03/08/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Age-related Macular Degeneration
Register for Updates