There are currently 925 clinical trials in Minneapolis, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Minnesota, Hennepin County Medical Center, Abbott Northwestern Hospital and University of Minnesota/Masonic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
The Teaspoon Study - Telefitting Spinal Cord Stimulation for Pain
NCT05741788
Recruiting
Spinal cord stimulation modulates the nervous system to effectively block pain signals originating from the back and legs. Spinal cord stimulation has been shown to improve chronic pain, improve quality of life, and reduce disability. Unfortunately, spinal cord stimulation has a high trial failure rate and a high long-term failure rate. This study consists of a prospective cohort of patients clinically scheduled to undergo spinal cord stimulation for the treatment of chronic back pain or radicul... Read More
Gender:
ALL
Ages:
22 years and above
Trial Updated:
10/17/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Spinal Cord Injuries, Chronic Pain
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CIFASD 5 tDCS and Cognitive Training
NCT05456321
Recruiting
This is a randomized placebo-controlled trial of cognitive training with transcranial direct current stimulation (tDCS) for children and adolescents (ages 8 - 17 years) with prenatal alcohol exposure (PAE).
Gender:
ALL
Ages:
Between 8 years and 17 years
Trial Updated:
10/17/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Fetal Alcohol Spectrum Disorders
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Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)
NCT05743244
Recruiting
A multi-center, placebo-controlled, double blind, 1:1:1 randomized control clinical trial testing two different JAK Inhibitors abrocitnib, ritlecitinib, and placebo in subjects with recent onset Stage 3 Type 1 Diabetes within 100 days of diagnosis.
Gender:
ALL
Ages:
Between 12 years and 35 years
Trial Updated:
10/17/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Diabetes Mellitus, Type 1
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Ruxolitinib, Human Chorionic Gonadotropin (uhCG/EGF), and Dose De-escalated Corticosteroids
NCT05123040
Recruiting
This multi-center center phase I/II study to establish the lowest possible recommended phase 2 dose (RP2D) of corticosteroids in conjunction with ruxolitinib and uhCG/EGF (a novel combination) for high-risk aGVHD. This is a single arm study designed to determine the lowest dose of corticosteroids required (toxicity endpoint) without impairing GVHD complete response or partial response (CR/PR) at day 28 when given in conjunction with uhCG/EGF and ruxolitinib. After completion of the corticoster... Read More
Gender:
ALL
Ages:
12 years and above
Trial Updated:
10/17/2024
Locations: Masonic Cancer Center at University of Minnesota, Minneapolis, Minnesota
Conditions: Acute-graft-versus-host Disease
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Test 2 Treat: Can we Improve the Testing and Treatment of High Cholesterol in Patients Who Have Been Hospitalized for a Cardiac Event by Providing Education to Doctors and Patients?
NCT06471036
Recruiting
The goal of this implementation trial is to learn if providing education to doctors and patients who have had a heart event works to prevent future heart problems. The main questions it aims to answer are: 1. Does educating the doctors in a health system improve how often patients in the hospital for a heart event have their cholesterol checked? 2. Can a "care champion" who calls patients who have been discharged from the hospital after a heart event help patients to achieve their cholesterol g... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/16/2024
Locations: Allina Health, Minneapolis, Minnesota
Conditions: ASCVD, LDL-C
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CompuFlo CathCheck
NCT06460155
Recruiting
The purpose of this study is to determine if the Compuflo CathCheck system is equivalent to an epidurogram in determining epidural catheter location (in or outside the epidural space), using the epidurogram as the gold standard. In short, this will be completed by performing an epidurogram (as is standard of practice and the gold standard of determining epidural placement) and compare it to the results of the Compuflo CathCheck system. Equivalency will be summarized through agreement and concord... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
10/11/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Epidural Placement
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Androgen Deprivation Therapy (ADT) and Pembrolizumab for Advanced Stage Androgen Receptor-positive Salivary Gland Carcinoma
NCT03942653
Recruiting
A Phase II, multi-center, single-arm, non-blinded study combining androgen deprivation therapy (ADT) and pembrolizumab for patients with metastatic or locally recurrent androgen receptor-positive salivary gland carcinoma, not amenable to surgery or radiation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/10/2024
Locations: University of Minnesota: Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Salivary Gland Carcinoma
Register for Updates
Community-based Exercise Following Revascularization for PAD
NCT04252950
Recruiting
The primary goal of this clinical trial is to evaluate whether a community-based structured exercise therapy (CB-SET) intervention, which could be accessible and easily disseminated, adds benefit to peripheral artery disease (PAD) patients undergoing revascularization (REVASC) to improve their function and cardiovascular health.
Gender:
ALL
Ages:
Between 40 years and 90 years
Trial Updated:
10/09/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Peripheral Artery Disease
Register for Updates
Feasibility of Identifying Brain Mechanisms of Qigong and Behavioral Outcomes After Qigong Practice in People With Chronic Low Back Pain
NCT04164225
Recruiting
The long-term objective of this investigation is to identify how Qigong affects brain function in brain areas relevant to patients with chronic low back pain (cLBP), thereby setting a foundation from which to perform further clinical research.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
10/08/2024
Locations: Children's Rehabilitation Center, 426 Church Street SE Room 302 - Brain Body Mind Lab Minneapolis, MN 55455, Minneapolis, Minnesota
Conditions: Low Back Pain
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Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma
NCT03858205
Recruiting
This phase II trial studies how well low-dose radiotherapy works in treating bone pain in patients with multiple myeloma that has spread to the bone. Radiation therapy uses high energy x-rays, gamma rays, neutrons, protons, or other sources to kill tumor cells and shrink tumors. Low-dose radiotherapy may be more convenient for patients and their families, may not interfere as much with the timing of chemotherapy, and may have less chance for short term or long-term side effects from the radiatio... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: University of Minnesota - Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Bone Pain, Metastatic Malignant Neoplasm in the Bone, Plasma Cell Myeloma
Register for Updates
Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure
NCT06507657
Recruiting
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce CVD events, including incident HF. SGLT2 is a glucose transport protein in the kidneys. Inhibition of this protein results in glucosuria and lower serum blood sugar. The SGLT2i medications were initially approved to treat type 2 diabetes (T2D). In 2015, Zinman et al. published the first large randomized clinical trial (RCT) demonstrating a lower composite CVD outcome in adults with T2D treated with empagliflozin compared to placebo (HR 0.... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
10/07/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Hypertension, Cardiovascular Diseases
Register for Updates
Biology of Osteosarcoma (BOOST) Registry and Biobank
NCT03225872
Recruiting
Osteosarcoma is very rare cancer of the bone. The investigator started the BOOST registry and biobank to make sure every patient has the opportunity to participate in research.
Gender:
ALL
Ages:
0 years and above
Trial Updated:
10/06/2024
Locations: Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Osteosarcoma
Register for Updates