There are currently 928 clinical trials in Minneapolis, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Minnesota, Hennepin County Medical Center, Abbott Northwestern Hospital and University of Minnesota/Masonic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Community-based Exercise Following Revascularization for PAD
NCT04252950
Recruiting
The primary goal of this clinical trial is to evaluate whether a community-based structured exercise therapy (CB-SET) intervention, which could be accessible and easily disseminated, adds benefit to peripheral artery disease (PAD) patients undergoing revascularization (REVASC) to improve their function and cardiovascular health.
Gender:
ALL
Ages:
Between 40 years and 90 years
Trial Updated:
10/09/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Peripheral Artery Disease
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Feasibility of Identifying Brain Mechanisms of Qigong and Behavioral Outcomes After Qigong Practice in People With Chronic Low Back Pain
NCT04164225
Recruiting
The long-term objective of this investigation is to identify how Qigong affects brain function in brain areas relevant to patients with chronic low back pain (cLBP), thereby setting a foundation from which to perform further clinical research.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
10/08/2024
Locations: Children's Rehabilitation Center, 426 Church Street SE Room 302 - Brain Body Mind Lab Minneapolis, MN 55455, Minneapolis, Minnesota
Conditions: Low Back Pain
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Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure
NCT06507657
Recruiting
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce CVD events, including incident HF. SGLT2 is a glucose transport protein in the kidneys. Inhibition of this protein results in glucosuria and lower serum blood sugar. The SGLT2i medications were initially approved to treat type 2 diabetes (T2D). In 2015, Zinman et al. published the first large randomized clinical trial (RCT) demonstrating a lower composite CVD outcome in adults with T2D treated with empagliflozin compared to placebo (HR 0.... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
10/07/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Hypertension, Cardiovascular Diseases
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Biology of Osteosarcoma (BOOST) Registry and Biobank
NCT03225872
Recruiting
Osteosarcoma is very rare cancer of the bone. The investigator started the BOOST registry and biobank to make sure every patient has the opportunity to participate in research.
Gender:
ALL
Ages:
0 years and above
Trial Updated:
10/06/2024
Locations: Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Osteosarcoma
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Non-Invasive and Non-Contact Intracranial Pressure Waveform Recording Using Dynamic Video Ophthalmoscopy
NCT04046523
Recruiting
This study will test the use of video ophthalmoscope to provide information about intracranial pressure without the use of invasive methods, anesthesia or contact with the eye.
Gender:
ALL
Ages:
4 years and above
Trial Updated:
10/06/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Intracranial Pressure Increase
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Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy
NCT05493722
Recruiting
Deep brain stimulation (DBS) is used to treat epilepsy in cases where patients are medically refractory and are not candidates for surgical resection. This therapy has been shown to be effective in seizure reduction, yet very few patients achieve the ultimate goal of seizure freedom. Implantable neural stimulators (INSs) have many parameters that may be adjusted, and could be tuned to achieve very patient specific therapies. This study will develop a platform for stimulation setting optimization... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/06/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Refractory Epilepsy, Deep Brain Stimulation
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State Dependence of Prefrontal Transcranial Magnetic Stimulation
NCT05962385
Recruiting
The study will examine whether the benefits of brain stimulation on mental functioning can be enhanced if an individual is actively engaging the target brain networks while receiving brain stimulation. The study includes two separate sessions and people will complete either a cognitive task or a perceptual task while receiving transcranial magnetic stimulation. The study will measure change in brain function with EEG.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/06/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Healthy
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Sodium Glucose Co-Transporter 2 (SGLT2) and STEMI
NCT05305911
Recruiting
The purpose of the research is to determine whether a class of medication called SGLT2 inhibitor will improve the heart's function and reduce its enlargement after a heart attack. Participation in this study will involve taking this class of medication (or a placebo) once daily for six months, one cardiac magnetic resonance imaging (MRI) test during your initial hospitalization, follow-up phone calls at 1 and 3 months, and one cardiac MRI and clinic visit at six months. This is a single center s... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
10/03/2024
Locations: Minneapolis Heart Institute Foundation, Minneapolis, Minnesota
Conditions: Heart Attack, Enlarged Heart
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Phase 1b Combo w/ Ribociclib, Alpelisib, or Everolimus
NCT05508906
Recruiting
This is a Phase 1b open-label, 2-part study in 3 treatment groups. The 3 treatment groups are as follows: Treatment Group 1: OP-1250 in combination with ribociclib (KISQALI®, Novartis Pharmaceuticals Corporation). Treatment Group 2: OP-1250 in combination with alpelisib (PIQRAY®, Novartis Pharmaceuticals Corporation). Treatment Group 3: OP-1250 in combination with everolimus.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/01/2024
Locations: Regents of the University of Minnesota, Minneapolis, Minnesota
Conditions: Metastatic Breast Cancer, Advanced Breast Cancer, HER2-negative Breast Cancer, ER-positive Breast Cancer, Breast Cancer
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A Placebo-controlled, Randomized Clinical Trial to Assess the Safety, Feasibility, and Pharmacokinetics of Microbiota Transplant Therapy With Antibiotic Preconditioning and Fiber Supplementation in Patients With Pulmonary Arterial Hypertension
NCT06481852
Recruiting
This pilot clinical trial will evaluate the initial safety, feasibility, and pharmacokinetics of microbiota transplant therapy (MTT) with antibiotic pre-conditioning and fiber supplementation vs. placebo in patients with pulmonary arterial hypertension (PAH). This trial will inform development of future trials of MTT as a treatment for PAH. 24 PAH patients will be randomized to receive either MTT with antibiotic preconditioning + fiber supplementation, MTT with antibiotic preconditioning + place... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
10/01/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Pulmonary Arterial Hypertension
Register for Updates
tDCS and Cognitive Training for Restrictive Eating Disorders
NCT06624150
Recruiting
This study looks at adults with restrictive eating disorders who are currently receiving outpatient treatment for their eating disorder to examine whether a new brain stimulation technique called non-invasive transcranial direct current stimulation (tDCS) can enhance brain training. Participation involves interviews, assessments, 10 sessions of brain stimulation (active or sham), and computerized brain training over a 3-4 week period, with one post-intervention visit, and one 1-month follow-up v... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/01/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Anorexia Nervosa, Atypical Anorexia Nervosa
Register for Updates
Molecular Epidemiology of Pediatric Germ Cell Tumors
NCT05564026
Recruiting
A Non-Therapeutic Study that aims to establish a cohort of GCT survivors to understand short term and long-term adverse effects of treatment and to conduct molecular analyses to improve risk stratification.
Gender:
ALL
Ages:
All
Trial Updated:
09/27/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Germ Cell Tumor, Germinoma, Teratoma, Embryonal Carcinoma, Yolk Sac Tumor, Choriocarcinoma, Mixed Germ Cell Tumor, Late Effects, Pediatric Germ Cell Tumor
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