There are currently 901 clinical trials in Minneapolis, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Minnesota, Hennepin County Medical Center, Abbott Northwestern Hospital and University of Minnesota/Masonic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Non-Invasive Cardiac Output Monitor (NICOM) for Goal-directed Fluid Resuscitation for Inpatients With Hypotension and/or Septic Shock
NCT05630716
Recruiting
The Non-Invasive Cardiac Output Monitor (NICOM) is a non-invasive monitor capable of measuring cardiac output (CO) and cardiac index (CI), and stroke volume (SV) and stroke volume index (SVI) based on heart rate. Conceptually NICOM is a technology that utilizes a dynamic response characteristic in assessing the need for fluid administration, whereby SVI is measured before and after a fluid challenge with more fluid given only if SVI increases significantly with administered fluid. Dynamic respon... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/31/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Sepsis, Hypotension, Septic Shock
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Neuroplasticity in RBD
NCT05471960
Recruiting
REM sleep behavior disorder is a parasomnia that reflects the presence of alpha-synucleinopathy in the brain and is highly predictive of eventual phenoconversion to Parkinson's disease, dementia with Lewy bodies, or multiple system atrophy over the course of years to decades. Neuroplastic adaptations in the brain during the prodromal stage of disease are thought to mask the expression of motor and non-motor signs and may substantially delay diagnosis during a potentially critical time window. Th... Read More
Gender:
All
Ages:
Between 21 years and 75 years
Trial Updated:
07/31/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Parkinson
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Sex Differences in the effecTs of brEaking uP Sedentary Behavior on vascUlar Function in Type 2 Diabetes
NCT05838586
Recruiting
Type 2 diabetes (T2D) confers a high risk of cardiovascular disease (CVD), particularly among older adults who tend to be physically inactive. Prolonged sedentary behavior (SB) has been shown to negatively influence markers of cardiovascular risk (e.g., blood glucose, blood pressure), even among individuals who are physically active. Most studies that have examined the effects of breaking up SB have focused on young healthy males and prioritized glycemic outcomes. Additionally, sex differences i... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
07/31/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Type 2 Diabetes, Cardiovascular Diseases
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Algorithms for Programming DBS Systems for ET
NCT03984643
Recruiting
Deep brain stimulation (DBS) targeting the Vim thalamus (ventralis intermedius nucleus) is an FDA-approved neuromodulation therapy for treating postural and action tremor in individuals with essential tremor (ET). The success of this treatment, however, is highly dependent on the ability of clinicians to identify therapeutic stimulation settings through a laborious programming process. There is a strong and growing clinical need for new approaches to provide clinicians with more efficient guidan... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
07/31/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Essential Tremor
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Assessment of Adherence, Quality of Life, Clinical Response and Safety of Daily and Long-Acting Growth Hormone Therapy
NCT04938466
Recruiting
The purpose of the study is to compare quality of life, adherence, insulin resistance, body composition and efficacy of long-acting growth hormone (LAGH) to daily growth hormone (DGH) in children with growth hormone deficiency (GHD). These objectives will be evaluated every 6 months for subjects prior to switch from DGH to LAGH, and 6 months after.
Gender:
All
Ages:
Between 2 years and 13 years
Trial Updated:
07/26/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Growth Hormone Deficiency, Growth Hormone Treatment
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Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors
NCT00785525
Recruiting
The purpose of the study is to: Establish and evaluate a system for collection of filgrastim-mobilized peripheral blood stem cells from National Marrow Donor Program donors (NMDP) donors Assess the safety among NMDP donors of filgrastim administration and PBSC leukapheresis Assess the safety and efficacy of filgrastim-mobilized PBSC in unrelated donor hematopoietic stem cell transplant recipients Determine the acceptability of stem cell donation by filgrastim stimulated apheresis in normal dono... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
07/21/2023
Locations: Be The Match, Minneapolis, Minnesota
Conditions: Healthy
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Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection
NCT05219110
Recruiting
The objective of this study is to determine if early high volume intravenous fluid administration (hyperhydration) may be effective in mitigating or preventing complications of shiga toxin-producing E. coli (STEC) infection in children and adolescents when compared with traditional approaches (conservative fluid management).
Gender:
All
Ages:
Between 9 months and 21 years
Trial Updated:
07/21/2023
Locations: Children's Minnesota Hospital, Minneapolis, Minnesota
Conditions: Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection, Hemolytic-Uremic Syndrome
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Lysosomal Acid Lipase (LAL) Deficiency Registry
NCT01633489
Recruiting
This is an observational, multi-center, international disease registry designed to collect longitudinal data and create a knowledge base that will be utilized to improve the care and treatment of patients with LAL Deficiency. Participation in the Registry by both physicians and patients is voluntary.
Gender:
All
Ages:
All
Trial Updated:
07/20/2023
Locations: Not set, Minneapolis, Minnesota
Conditions: Lysosomal Acid Lipase Deficiency, Cholesterol Ester Storage Disease, Wolman Disease, Acid Cholesteryl Ester Hydrolase Deficiency, Type 2, Acid Lipase Deficiency, LIPA Deficiency, LAL-Deficiency
Register for Updates
ALS/MND Natural History Study Data Repository
NCT05966038
Recruiting
This is a data repository for multi-site multi-protocol clinic-based Natural History Study of ALS and Other Motor Neuron Disorders (MND). All people living with ALS or other MNDs who attend clinics at the Study hospitals (sites) are offered to participate in the Study. The Sites collect so-called Baseline information including demographics, disease history and diagnosis, family history, etc. At each visit, the Sites also collect multiple disease-specific outcome measures and events. The inform... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
07/20/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: ALS, PLS, MND (Motor Neurone DIsease), Kennedy Disease, PMA - Progressive Muscular Atrophy, PBP - Progressive Bulbar Palsy
Register for Updates
Social Buffering During Aversive Conditioning
NCT04312945
Recruiting
The purpose of this experiment is to determine the mechanisms through which parental buffering of stress physiology during aversive conditioning diminishes with pubertal development and whether this diminution of effectiveness extends to social buffering by peers (best friends) and/or other unfamiliar social partners (e.g., experimenters).
Gender:
All
Ages:
Between 11 years and 14 years
Trial Updated:
07/19/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Social Stress, Adolescent Behavior
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Registry of Avance® Nerve Graft's Utilization and Recovery Outcomes Post Peripheral Nerve Reconstruction
NCT01526681
Recruiting
This study is a registry of general use of Avance Nerve Graft and is intended to evaluate the uses, response rates, and safety of Avance Nerve Graft in the real-life clinical setting. Optional addendums 1 and 2 included in the protocol are intended to establish comparative groups and focused subgroups within the registry.
Gender:
All
Ages:
All
Trial Updated:
07/17/2023
Locations: MATCH: Hennepin County Medical Center, Minneapolis, Minnesota
Conditions: Peripheral Nerve Injuries
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Theta Phase-specific TMS to Modulate Prefrontal Activity
NCT05416138
Recruiting
The purpose of this study is to evaluate the causal link between the phase of ongoing theta oscillations in the prefrontal cortex and approach/avoidance (Ap/Av) behavior in adults using theta phase-specific transcranial magnetic stimulation (TMS).
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
07/17/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Approach/Avoidance Behavior
Register for Updates