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Depression Clinical Trials in Rochester, MN
A listing of 5 Depression clinical trials in Rochester, MN actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 5 of 5
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The city of Rochester, Minnesota, currently has 5 active clinical trials seeking participants for Depression research studies.
Featured Trial
Studying an Investigational Drug as Additional Therapy Treatment for Depression
Recruiting
This phase 2/3 study aims to assess the safety and effectiveness of an investigational drug (SEP-363856) as an additional treatment for adults with Major Depressive Disorder and who have not had success with antidepressants in treating their depression symptoms. This study may be suitable for you if you have been diagnosed with depression and your previous antidepressant treatments have not been effective. Should you express interest, the research site will contact you directly to provide further details and address any questions you may have about study requirements, risks/benefits, and compensation.
Conditions:
Depression
Depressive disorder
All Conditions
Featured Trial
Narcolepsy Clinical Study
Recruiting
The Vibrance Studies are researching the safety and effectiveness of a once-daily oral investigational study drug and how it may work in adults 18–70 years of age for the potential treatment of excessive daytime sleepiness (EDS) symptoms in adults with narcolepsy type 1 (NT1) or narcolepsy type 2 (NT2).
All participants who qualify will receive the study drug or placebo (a tablet that looks like the study drug but contains no active medicine), as well as study-related procedures and study-related laboratory tests at no cost. Compensation for time and travel may also be available.
All participants who qualify will receive the study drug or placebo (a tablet that looks like the study drug but contains no active medicine), as well as study-related procedures and study-related laboratory tests at no cost. Compensation for time and travel may also be available.
Conditions:
Narcolepsy
Narcolepsy With Cataplexy
Narcolepsy Without Cataplexy
Narcolepsy 1
Narcolepsy Type 1
Featured Trial
Type 2 Diabetes Clinical Trial
Recruiting
Can changing your breakfast improve your type 2 diabetes? If you have an HbA1C of 7.0% or higher, you are invited to participate in an online study at the University of Michigan.
Conditions:
Type 2 Diabetes
Diabetes Mellitus Type 2 in Obese
Diabetes Type Two
Type 2 Diabetes Mellitus
Diabete Type 2
Featured Trial
High Triglyceride Clinical Research Study
Recruiting
Living with high triglycerides? See if our clinical study is right for you.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Conditions:
High Triglycerides
High Triglyceride Level
Hypertriglyceridemia
Elevated Triglycerides
Triglycerides High
Featured Trial
Studying an Investigational Medication's Impact on Cardiovascular Events
Recruiting
The main objectives of this Phase 3 study are to evaluate the safety and effectiveness of an investigational medication's ability to reduce major adverse cardiovascular events (such as heart attacks and strokes) in adults at risk. Participants will be randomly assigned to receive either the investigational medication or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
All Conditions
Hyperlipidemia
Cardiovascular Disease
Ischemic heart disease (IHD)
Stroke
Featured Offer
Lose Weight with GLP-1 Medications
Recruiting
Policy Lab has partnered with CareGLP to offer trusted access to GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®.
GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.
As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.
GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.
As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.
Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
Transcranial Direct Current Stimulation (tDCS) as an Adjunctive Treatment for Treatment Resistant Depression (TRD)
Recruiting
The researchers are trying to test the feasibility and acceptability of using transcranial Direct Current Stimulation (tDCS) in hospitalized adult patients with Treatment Resistant Depression (TRD), assess for any preliminary effect on depressive and cognitive symptoms, and explore the utility of biomarkers to assess response to tDCS.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/10/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Treatment Resistant Depression
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
Recruiting
The goal of this clinical trial is to evaluate the effectiveness and safety of bilateral stimulation of the subcallosal cingulate white matter (SCCwm) using Deep Brain Stimulation (DBS) as an adjunctive treatment of non-psychotic unipolar Major Depressive Disorder (MDD) in adults.
Gender:
ALL
Ages:
Between 22 years and 70 years
Trial Updated:
03/31/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Treatment Resistant Depression
Effect of Vagal Nerve Stimulation on Gastric Motor Functions
Recruiting
The specific aim of this study is to compare simultaneous assessment of gastric emptying and gastric accommodation in response to the same caloric meal before and three months after activation of left cervical VNS. Our hypothesis is that cervical VNS increases gastric accommodation and accelerates gastric emptying.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/14/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Epilepsy, Depression
8 Week Multi-site Study of MYDAYIS® for Bipolar Depression
Recruiting
This protocol is a Phase 2 multi-site study which aims to evaluate the safety and effectiveness of MYDAYIS\® as adjunctive therapy for adults with bipolar depression. Results from this study WILL NOT be used to contribute to an approval of MYDAYIS \® for this indication.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
03/12/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Bipolar Depression
Intravenous Ketamine for Treatment-Resistant Depression
Recruiting
The purpose of this study is to to evaluate the relationships between peak (% change from baseline) central GABA and Glu levels during a 40-min IV ketamine or normal saline infusion utilizing fMRS, and change in peripheral GABA and Glu levels from baseline to 24-hr postinfusion utilizing LCMS, with baseline to 24-hr post-infusion change in depression (MADRS) in 30 TRD adults.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
03/06/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Depressive Disorder, Treatment-Resistant, Treatment Resistant Depression (TRD)
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