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Depression Clinical Trials in Rochester, MN
A listing of 4 Depression clinical trials in Rochester, MN actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 4 of 4
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Clinical Trial Phase
The city of Rochester, Minnesota, currently has 4 active clinical trials seeking participants for Depression research studies.
Featured Trial
Healthy Participants Needed (Colonoscopy + Cancer Screening)
Recruiting
Earn $325 - $475 in electronic payment card compensation for your time and effort by participating in a clinical study to develop a blood test that may one day help screen for colon cancer. Take a quick quiz to see if you qualify.
Conditions:
Healthy
Healthy Volunteers
Healthy Subjects
Healthy Volunteer
Healthy Participants
Featured Therapy
Unique Treatment for High Blood Pressure
Worried about high blood pressure? Think beyond typical high blood pressure treatments.
People who may be candidates for this procedure:
• Are at least 18 years old
• Have been unable to manage their high blood pressure with medications or lifestyle changes alone¹
Learn about a safe and effective procedure that may help reduce high blood pressure. See if you qualify today.
¹ Kandzari DE, et al. J Am Coll Cardiol. Nov 7, 2023;82(19):1809-1823.
People who may be candidates for this procedure:
• Are at least 18 years old
• Have been unable to manage their high blood pressure with medications or lifestyle changes alone¹
Learn about a safe and effective procedure that may help reduce high blood pressure. See if you qualify today.
¹ Kandzari DE, et al. J Am Coll Cardiol. Nov 7, 2023;82(19):1809-1823.
Conditions:
High Blood Pressure
High Blood Pressure (& [Essential Hypertension])
High Blood Pressure (Hypertension).
Hypertension
Essential Hypertension
Featured Trial
ASCVD B Clinical Study
Recruiting
A clinical study for people that suffer with ASCVD
Conditions:
ASCVD B
ASCVD
Atherosclerotic Cardiovascular Disease
Atherosclerotic Cardiovascular Disease (ASCVD)
Atherosclerotic Cardiovascular Diseases
Featured Trial
ASCVD A Clinical Study
Recruiting
A clinical study for people that suffer with ASCVD
Conditions:
ASCVD A
ASCVD
Atherosclerotic Cardiovascular Disease (ASCVD)
Atherosclerotic Cardiovascular Disease
Atherosclerotic Cardiovascular Diseases
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Semaglutide and Tirzepatide are advanced GLP-1 medications designed to support weight management and metabolic health. They work by targeting GLP-1 receptors in the body, helping regulate appetite, improve blood sugar control, and support sustainable weight loss.
Conditions:
Overweight
Overweight and Obesity
Featured Trial
Type 1 Diabetes (T1DM) Clinical Study
Recruiting
A clinical study for people that suffer with Type 1 Diabetes (T1DM)
Conditions:
Type 1 Diabetes (T1DM)
Type 1 Diabetes
Diabetes Mellitus
Type 1
Type 1 Diabetes Mellitus (T1DM)
Intravenous Ketamine for Treatment-Resistant Depression
Recruiting
The purpose of this study is to to evaluate the relationships between peak (% change from baseline) central GABA and Glu levels during a 40-min IV ketamine or normal saline infusion utilizing fMRS, and change in peripheral GABA and Glu levels from baseline to 24-hr postinfusion utilizing LCMS, with baseline to 24-hr post-infusion change in depression (MADRS) in 30 TRD adults.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/19/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Depressive Disorder, Treatment-Resistant, Treatment Resistant Depression (TRD)
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
Recruiting
The goal of this clinical trial is to evaluate the effectiveness and safety of bilateral stimulation of the subcallosal cingulate white matter (SCCwm) using Deep Brain Stimulation (DBS) as an adjunctive treatment of non-psychotic unipolar Major Depressive Disorder (MDD) in adults.
Gender:
ALL
Ages:
Between 22 years and 70 years
Trial Updated:
07/07/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Treatment Resistant Depression
Effect of Vagal Nerve Stimulation on Gastric Motor Functions
Recruiting
The specific aim of this study is to compare simultaneous assessment of gastric emptying and gastric accommodation in response to a caloric meal In patients who have previously undergone activation of left cervical VNS for the treatment of medication-resistant depression. Our hypothesis is that cervical VNS increases gastric accommodation and accelerates gastric emptying compared to a bank of healthy control data.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/03/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Epilepsy, Depression
Transcranial Direct Current Stimulation (tDCS) as an Adjunctive Treatment for Treatment Resistant Depression (TRD)
Recruiting
The researchers are trying to test the feasibility and acceptability of using transcranial Direct Current Stimulation (tDCS) in hospitalized adult patients with Treatment Resistant Depression (TRD), assess for any preliminary effect on depressive and cognitive symptoms, and explore the utility of biomarkers to assess response to tDCS.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/10/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Treatment Resistant Depression
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