The city of Rochester, Minnesota, currently has 20 active clinical trials seeking participants for Healthy research studies.
A Study of Pulmonary Hypertension Peripheral Limitations
Recruiting
The investigators are doing this research study to compare whole body aerobic training with isolated leg training (with weights) and its impact on effectiveness in symptoms and quality of life in patients with Pulmonary Arterial Hypertension (PAH).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/31/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Pulmonary Arterial Hypertension, Healthy
Adipose Tissue Blood Flow in Aging Humans
Recruiting
The goal of this basic science clinical trial is to understand whether adipose tissue blood flow changes between younger and older healthy adults. The main question\[s\] it aims to answer are: * Is basal and nutrient responsive adipose tissue blood flow (ATBF) different between younger and older adults * What molecular and systemic signatures related to adipose tissue blood flow are altered between these two groups. Participants will undergo measurements of adipose tissue blood flow using the... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/17/2025
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Healthy, Aging
A Study of Invasive Hemodynamic for MACHD Registry
Recruiting
This research study is being done to provide comparative data to the Mayo Clinic Adult Congenital Heart Disease Registry.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/21/2025
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Healthy, Congenital Heart Disease
A Study of Adipose Tissue in Adaptive Responses to Exercise
Recruiting
The purpose of this research is to determine how exercise affects fat (adipose) tissue and how changes to adipose tissue that occur during and after exercise might improve health in aging and obesity.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
02/06/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy, Obesity
A Comparison of Neuromuscular Recruitment in Trained and Untrained Adults
Recruiting
The objective of the study is to use neurological techniques to obtain quantitative measurements of nervous system control of skeletal muscle activity in adults aged 60-85 who are either long-term resistance exercisers or who are untrained.
Gender:
ALL
Ages:
Between 60 years and 85 years
Trial Updated:
02/05/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy, Insulin Resistance
The Effect of Synaquell™ in Contact Sport Athletes
Recruiting
This research is being done to investigate the dietary supplement, Synaquell (TM), for effects on brain function in youth contact sport athletes.
Gender:
ALL
Ages:
Between 13 years and 19 years
Trial Updated:
02/04/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
Intracardiac Flow Assessment in Cardiac Amyloidosis
Recruiting
The primary objective of this study is to define the intracardiac flow imaging biomarkers in cardiac amyloidosis.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
01/09/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Amyloidosis Cardiac, Healthy Adults
A Study to Evaluate Non-significant Risk Operation Magnetic Resonance Imaging for MRI Guided Ablation
Recruiting
The result of these studies will be used to improve patient care through assessment of new technology to determine whether it is beneficial (i.e. improving data acquisition speed or image quality) during iMRI procedures.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/08/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
CArdioMEtabolic Function and Reserve Capacity in Healthy Adults: The CAMERA Study
Recruiting
The purpose of this study is to evaluate pulmonary capillary wedge pressure (PCWP) and other hemodynamic measurements at rest and during exercise in healthy volunteers across the age spectrum.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/08/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
Studying the Hedonic and Homeostatic Regulation of Food Intake Using Functional MRI
Recruiting
The purpose of this study is to investigate how gut hormones and brain areas respond differently to gastric distention, tasteless calories, or palatable food and how this alters appetite.
Gender:
ALL
Ages:
Between 21 years and 50 years
Trial Updated:
01/07/2025
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Healthy
Saccharomyces Boulardii CNCM I-745 on Intestinal Barrier Function
Recruiting
This study is being done to assess the effects of S. boulardii CNCM I-745 compared to placebo on impaired intestinal permeability, which is the control of material passing from inside the gastrointestinal tract through the cells lining the gut wall into the rest of the body.
Gender:
ALL
Ages:
Between 25 years and 65 years
Trial Updated:
01/02/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy
A Study to Evaluate the Effect of Genetic Variation on Beta-cell Function During Fasting and Hyperglycemia in Nondiabetics
Recruiting
The GLP-1 receptor (GLP1R) gene is found on the beta cells of the pancreas. Its role is in the control of blood sugar level by enhancing insulin secretion from the pancreas after eating a meal. The purpose of this research study to find out how genetic variations in GLP1R alter insulin secretion, in the fasting state and when blood sugars levels are elevated.
Gender:
ALL
Ages:
Between 25 years and 65 years
Trial Updated:
11/29/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy