The city of Rochester, Minnesota, currently has 20 active clinical trials seeking participants for Healthy research studies.
A Study to Evaluate Breathing Muscle Training in Cardiac Rehab
Recruiting
The purpose of this study is to understand if breathing muscle training combined with cardiac rehabilitation influences the blood flow and blood pressure response during exercise.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/14/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy, Heart Failure
Intracardiac Flow Assessment in Cardiac Amyloidosis
Recruiting
The primary objective of this study is to define the intracardiac flow imaging biomarkers in cardiac amyloidosis.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
07/10/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Amyloidosis Cardiac, Healthy Adults
A Study to Evaluate the Effect of Genetic Variation on Beta-cell Function During Fasting and Hyperglycemia in Nondiabetics
Recruiting
The GLP-1 receptor (GLP1R) gene is found on the beta cells of the pancreas. Its role is in the control of blood sugar level by enhancing insulin secretion from the pancreas after eating a meal. The purpose of this research study to find out how genetic variations in GLP1R alter insulin secretion, in the fasting state and when blood sugars levels are elevated.
Gender:
ALL
Ages:
Between 25 years and 65 years
Trial Updated:
07/01/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
A Study to Analyze the Role of Sympathetic Nervous System in Spontaneous Coronary Artery Dissection
Recruiting
The purpose of this research is to compare sympathetic function (flight or fight system) and arterial health including structure and mechanics of participants with history of spontaneous coronary artery dissection (SCAD) to age and sex matched control participants.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
06/10/2025
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Spontaneous Coronary Artery Dissection, Healthy
A Comparison of Neuromuscular Recruitment in Trained and Untrained Adults
Recruiting
The objective of the study is to use neurological techniques to obtain quantitative measurements of nervous system control of skeletal muscle activity in adults aged 60-85 who are either long-term resistance exercisers or who are untrained.
Gender:
ALL
Ages:
Between 60 years and 85 years
Trial Updated:
06/04/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy, Insulin Resistance
Glucagon Suppression by Hyperglycemia in the Presence and Absence of Amino Acid Infusion
Recruiting
This study is being done to better understand how amino acids alter the release of glucagon and insulin compared to glucose alone in health and disease.
Gender:
ALL
Ages:
Between 25 years and 65 years
Trial Updated:
05/30/2025
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Healthy, Type 2 Diabetes, Obesity
The Effect of Synaquell™ in Contact Sport Athletes
Recruiting
This research is being done to investigate the dietary supplement, Synaquell (TM), for effects on brain function in youth contact sport athletes.
Gender:
ALL
Ages:
Between 13 years and 19 years
Trial Updated:
05/07/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells
Recruiting
This pilot study will first establish the feasibility of an in vivo methodology of assessing the utilization of glutamine into the TCA cycle of normal bone marrow plasma cells from healthy subjects while comparing it to an ex vivo approach
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
04/16/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy
Registry for Mayo Clinic Adult Congenital Heart Disease Control Population
Recruiting
This research study is being done to provide comparative data to the Mayo Clinic Adult Congenital Heart Disease Registry.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
03/31/2025
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Healthy
A Study of Pulmonary Hypertension Peripheral Limitations
Recruiting
The investigators are doing this research study to compare whole body aerobic training with isolated leg training (with weights) and its impact on effectiveness in symptoms and quality of life in patients with Pulmonary Arterial Hypertension (PAH).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/31/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Pulmonary Arterial Hypertension, Healthy
Adipose Tissue Blood Flow in Aging Humans
Recruiting
The goal of this basic science clinical trial is to understand whether adipose tissue blood flow changes between younger and older healthy adults. The main question\[s\] it aims to answer are: * Is basal and nutrient responsive adipose tissue blood flow (ATBF) different between younger and older adults * What molecular and systemic signatures related to adipose tissue blood flow are altered between these two groups. Participants will undergo measurements of adipose tissue blood flow using the... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/17/2025
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Healthy, Aging
A Study of Invasive Hemodynamic for MACHD Registry
Recruiting
This research study is being done to provide comparative data to the Mayo Clinic Adult Congenital Heart Disease Registry.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/21/2025
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Healthy, Congenital Heart Disease