There are currently 32 active clinical trials seeking participants for Endometriosis research studies. The states with the highest number of trials for Endometriosis participants are Florida, Texas, California and Ohio.
Histologic Comparison of Ablative Techniques for Endometriosis
Recruiting
To our knowledge, no other human studies directly compare the effectiveness of the various ablative technologies. We set out to design a study to directly compare ablative energy sources and evaluate their ability to destroy native endometriosis tissue in humans.
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/28/2024
Locations: Good Samaritan Hospital, Cincinnati, Ohio
Conditions: Endometriosis, Endometriosis-related Pain, Endometriosis Pelvic, Endometriosis; Peritoneum
Deep Neural Network Stratification for Use Detecting Endometriosis in Women Affected by Chronic Pelvic Pain (EndoCheck)
Recruiting
The goal of this observational study is to determine the clinical validity of a deep neural network algorithm that utilizes protein biomarker detection of Endometriosis - "EndoCheck" - as an "aid in diagnosis" for endometriosis and to show validity as a diagnostic test
Gender:
FEMALE
Ages:
Between 14 years and 50 years
Trial Updated:
01/24/2025
Locations: New Horizons Clinical Trials, Chandler, Arizona +10 locations
Conditions: Endometriosis
Cardiovascular Disease Risk in Women With Endometriosis
Recruiting
To test the hypothesis that estrogen suppression impairs endothelial dysfunction in endometriosis.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
01/23/2025
Locations: Yale School of Medicine, New Haven, Connecticut
Conditions: Endometriosis
Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone PET / MRI
Recruiting
Purpose: The aim of this study is to assess the sensitivity and specificity of FFNP PET/MRI for diagnosis of endometriosis. Participants: A total of 24 participants will be recruited from individuals with clinically suspected endometriosis. Procedures (methods): This is a prospective, one arm, single center study of 24 subjects with clinically suspected endometriosis to demonstrate FFNP PET-MRI's clinical utility for diagnosis of endometriosis.
Gender:
FEMALE
Ages:
Between 18 years and 55 years
Trial Updated:
01/21/2025
Locations: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Conditions: Endometriosis
Endometriosis and Migraine
Recruiting
This study aims to determine differences in experimental pain and sex hormone levels between patients with migraine, patients with endometriosis, patients with migraine and endometriosis, and healthy controls. Participants will complete surveys, experimental pain paradigms and collection of samples for hormone analyses.
Gender:
FEMALE
Ages:
Between 12 years and 45 years
Trial Updated:
01/15/2025
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Migraine, Endometriosis
Endometriosis Pain
Recruiting
Aim 1. To determine the factors contributing to pain in patients with chronic pelvic pain with and without endometriosis Aim 2. To determine the changes following endometriosis lesion removal surgery in pain and sex hormone levels. Aim 3. To identify factors predicting clinical pain reduction after lesion removal surgery. Additional exploratory aims might compare subgroups of patients such as patients with vs. without endometriosis, with vs. without additional chronic pain syndromes, and with... Read More
Gender:
FEMALE
Ages:
Between 12 years and 45 years
Trial Updated:
01/14/2025
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Pelvic Pain, Endometriosis
Study Of Oral Elagolix Tablets In Combination With Combined Oral Contraceptive Capsules/Tablets To Assess Dysmenorrhea Response In Adult Female Participants With Endometriosis And Associated Moderate To Severe Pain
Recruiting
Endometriosis is a painful disorder of the uterus affecting 6-10% of women of childbearing age. Endometriosis affects daily activities, social relationships, sexuality and sexual activity, and mental health. This study will evaluate how well elagolix in combination with combined oral contraceptives (COC) works within the body and/or how safe it is compared to placebo (does not contain treatment drug). This study will assess the dysmenorrhea (painful periods) response in participants with endomet... Read More
Gender:
FEMALE
Ages:
Between 18 years and 49 years
Trial Updated:
01/01/2025
Locations: Pinnacle Research Group /ID# 217062, Anniston, Alabama +178 locations
Conditions: Endometriosis
The Effect of Medical Management Following Excisional Surgery for Endometriosis: A Randomized Controlled Trial
Recruiting
The goal of this investigator-initiated single-site clinical trial is to compare the overall quality of life of participants taking Relugolix combination therapy (Rel-CT) following excisional surgery for endometriosis to participants that do not take Rel-CT following the same surgery. Rel-CT is an FDA approved form of medical treatment for endometriosis. It is known to work in treating endometriosis pain. However, investigators do not know whether or not there is a benefit to beginning Rel-CT im... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: Main Line Health, Wynnewood, Pennsylvania
Conditions: Endometriosis
Evaluating the Impact of a Novel Cannabinoid Product for Endometriosis
Recruiting
Despite the proliferation of cannabis and cannabinoid products in recent years, little research has been done to determine the impact of these products on womens health conditions, including endometriosis. This study is designed to assess the impact of a custom-formulated, hemp-derived, full-spectrum, high-CBD product vs. placebo on clinical symptoms and biomarkers over the course of 12 weeks of treatment in patients with endometriosis. This project will provide information that does not current... Read More
Gender:
FEMALE
Ages:
21 years and above
Trial Updated:
11/18/2024
Locations: McLean Hospital, Belmont, Massachusetts
Conditions: Endometriosis
Comparison of Proton or Intensity Modulated Radiation Therapy After Surgery for Endometrial or Cervical Cancer
Recruiting
This early phase I trial compares the side effects between patients treated with proton radiation therapy versus intensity modulated radiation therapy after surgery for the treatment of endometrial or cervical cancer. Radiation therapy uses high energy protons or x-rays to kill tumor cells and shrink tumors. Using quality of life questionnaires and adverse event assessments may help doctors learn whether proton radiation therapy is associated with lower acute gastrointestinal toxicities at the e... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: Mayo Clinic in Arizona, Scottsdale, Arizona +2 locations
Conditions: Cervical Carcinoma, Endometrial Carcinoma, Endometriosis, Pelvic Inflammatory Disease
Nutritional Intervention for Endometriosis
Recruiting
In a 12-week parallel study, women with a verified diagnosis of endometriosis will be randomly assigned to follow a low-fat plant-based diet or to stay on their usual diets for 12 weeks. Participants in both groups will be asked to make no changes to their exercise patterns for the study period. Changes in pain, quality of life, and inflammatory biomarkers from baseline to final will be the primary outcomes. Secondary outcomes will include changes in body weight, blood lipids, gut microbiome com... Read More
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
11/04/2024
Locations: Physicians Committee for Responsible Medicine, Washington, DC, District of Columbia
Conditions: Endometriosis
Endometriosis and Microvascular Dysfunction; Simvastatin and Duavee
Recruiting
Purpose: To determine the effects of SERM and simvastatin interventions on endothelial dysfunction in women with endometriosis. Hypothesis: Treatment with the SERM (bazedoxifene + conjugated estrogen) or with simvastatin will decrease systemic inflammation and improve specific measures of cardiovascular function including endothelium-dependent vasodilation.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
11/04/2024
Locations: The John B. Pierce Laboratory, New Haven, Connecticut
Conditions: Endometriosis