There are currently 474 clinical trials in Kansas City, Missouri looking for participants to engage in research studies. Trials are conducted at various facilities, including Children's Mercy Hospital, Research Medical Center, Saint Luke's Hospital of Kansas City and CCOP - Kansas City. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS
NCT05267821
Recruiting
The TRIPS study is a prospective, multi-center, double-blind, adaptively randomized, placebo-controlled clinical trial of the drug anakinra for reversal of moderate to severe hyperinflammation in children with sepsis-induced multiple organ dysfunction syndrome (MODS).
Gender:
All
Ages:
Between 1 day and 17 years
Trial Updated:
02/07/2023
Locations: Mercy Children's Hospital, Kansas City, Missouri
Conditions: Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)
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GM-CSF for Reversal of Immunoparalysis in Pediatric Sepsis-induced MODS
NCT05266001
Recruiting
The GRACE-2 study is a prospective, multi-center, double-blind, randomized controlled trial of the drug GM-CSF vs placebo in children with sepsis-induced multiple organ dysfunction syndrome (MODS) who have immunoparalysis with mild to moderate inflammation.
Gender:
All
Ages:
Between 1 day and 17 years
Trial Updated:
02/07/2023
Locations: Mercy Children's Hospital, Kansas City, Missouri
Conditions: Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome
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Tg01 Vaccine / Qs-21 Stimulon™ With Or Without Balstilimab As Maintenance Therapy Following Adjuvant Chemotherapy In Patients With Resected Pancreatic Cancer
NCT05638698
Recruiting
Researchers want to discover if the new drug "TG01" will work with participants' bodies to help their immune system attack any cancer cells that might still be in the blood stream after surgery for pancreatic cancer. The researchers will also investigate whether or not "TG01" combined with the other study drug, "Balstilimab", will show even greater efficacy. TG01 and Balstilimab are both experimental treatments and are not approved by the US Food and Drug Administration (FDA) as treatment in t... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/30/2023
Locations: University of Kansas Cancer Center - North, Kansas City, Missouri
Conditions: Pancreas Cancer
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AngioSafe Peripheral CTO Crossing System Study (RESTOR-1 Study)
NCT04663867
Recruiting
The study is designed to evaluate the safety and efficacy of the AngioSafe Peripheral CTO Crossing System.
Gender:
All
Ages:
22 years and above
Trial Updated:
11/22/2022
Locations: Saint Luke's Hospital of Kansas City, Kansas City, Missouri
Conditions: Peripheral Artery Occlusion, Peripheral Arterial Disease
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MyLeukoMAP™ Genomic Survival Prediction Assay Pivotal Clinical Study
NCT05258942
Recruiting
The MyLeukoMAP™ Pivotal Clinical Study will assess the accuracy of MyLeukoMAP™, a new molecular blood test, performed within 30 days before scheduled surgical / interventional therapies for Heart Failure, to determine its effectiveness in improving clinical decision support by providing a quantitative prediction of low, indeterminate, or high risk of death one year after surgical / interventional therapies that is not identified by current diagnostic tools.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/25/2022
Locations: Saint Luke's Hospital of Kansas City, Kansas City, Missouri
Conditions: Heart Failure
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Anti-Reflux Endoscopic TX Using APC (AREA) in GERD Patients: (The AREA Study)
NCT05570448
Recruiting
This will be a randomized clinical trial examining the efficacy and safety of ARAT (intervention group) in patients with chronic GERD symptoms (typical symptoms of GERD, i.e. heartburn or acid reflux/regurgitation at least twice a week) for the last 6 months. Patients must have a positive pH test and a negative manometry (no treatment) procedure.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
10/05/2022
Locations: Kansas City VA Hospital, Kansas City, Missouri
Conditions: Gastro Esophageal Reflux
Register for Updates
Ovarian Morphology in Girls
NCT04424576
Recruiting
Establishment of regular menstrual cycles is a key component of reproductive maturation and a recognized vital sign for health and well-being. Irregular menstrual cycles are especially common for the first 2-3 years after an adolescent's first menstrual period (i.e., menarche), which delays the identification and diagnosis of early reproductive disturbances such as polycystic ovary syndrome (PCOS). The purpose of this research study is to determine whether the ovary can serve as a reliable predi... Read More
Gender:
Female
Ages:
Between 9 years and 17 years
Trial Updated:
09/23/2022
Locations: Children's Mercy Hospital, Kansas City, Missouri
Conditions: Amenorrhea, Oligomenorrhea, Puberty
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Artisan Aphakia Lens for the Correction of Aphakia in Children
NCT01547442
Recruiting
The purpose of this study is to determine the safety and effectiveness of the Artisan Aphakia Lens in the treatment of aphakia in children.
Gender:
All
Ages:
Between 2 years and 21 years
Trial Updated:
06/24/2022
Locations: Children's Mercy Hospital and Clinics, Kansas City, Missouri
Conditions: Aphakia
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Rib Fixation for Clinically Severe Rib Fractures From Trauma
NCT02595593
Recruiting
This is a multicenter randomized study investigating the differences in clinical outcomes of patients between two standard of care pathways for rib trauma: patients who receive rib fixation versus patients who receive modern critical care and pain control after sustaining clinically significant rib fractures from trauma.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
05/07/2022
Locations: Research Medical Center, Kansas City, Missouri
Conditions: Rib Fracture, Flail Chest
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Linking Novel Diagnostics With Data-Driven Clinical Decision Support in the Emergency Department
NCT05335135
Recruiting
The primary objective of this study is to validate the use of an electronic clinical decision support (CDS) tool, TriageGO with Monocyte Distribution Width (TriageGO-MDW), in the emergency department (ED). TriageGO-MDW is non-device CDS designed to support emergency clinicians (nurses, physicians and advanced practice providers) in performing risk-based assessment and prioritization of patients during their ED visit. This study will follow an effectiveness-implementation hybrid design via the fo... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/11/2022
Locations: University Health Truman Medical Center, Kansas City, Missouri
Conditions: Inpatient Hospitalization, Intensive Care Unit Admission, Inpatient Mortality, Sepsis and Septic Shock
Register for Updates
Introducing Palliative Care (PC) Within the Treatment of End Stage Liver Disease (ESLD)
NCT03540771
Recruiting
This is a comparative effectiveness study of two pragmatic models aiming to introduce palliative care for end stage liver disease patients. The 2 comparators are: Model 1: Consultative Palliative Care (i.e. direct access to Palliative Care provider), Model 2: Trained Hepatologist- led PC intervention (i.e. a hepatologist will receive formal training to deliver Palliative Care services) Primary Outcome: The change in quality of life from baseline to 3 months post enrollment as assessed by FACT-... Read More
Gender:
All
Ages:
Between 18 years and 120 years
Trial Updated:
04/05/2022
Locations: Kansas City VA Medical Center, Kansas City, Missouri
Conditions: End Stage Liver Disease
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Study of Safety and Efficacy of ANG-3070 in Chronic Kidney Disease
NCT04939116
Recruiting
The major objective is to demonstrate the safety and efficacy of ANG-3070 in patients with primary glomerular disease and persistent proteinuria.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/22/2022
Locations: Clinical Research Consultants, LLC., Kansas City, Missouri
Conditions: Glomerular Disease, Proteinuria
Register for Updates