The state of Nebraska currently has 3 active clinical trials seeking participants for Parkinson's Disease research studies. These trials are conducted in various cities, including Omaha, Lincoln, Kearney and Grand Island.
Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease (Aim 2)
Recruiting
Parkinson's Disease (PD) is the second most common of the age-related neurodegenerative disorders, affecting over 1,900 adults per 100,000 over the age of 80 in the US. The prevalence of sleep dysfunction in PD is estimated at nearly 80-90% which includes sleep fragmentation, insomnia, rapid eye movement (REM or dream sleep) Sleep Behavior Disorder (RBD), Restless legs syndrome (RLS), periodic limb movement, excessive daytime sleepiness, and sleep apnea. Sleep is vital to homeostasis, cognition,... Read More
Gender:
ALL
Ages:
Between 19 years and 80 years
Trial Updated:
05/16/2025
Locations: University of Nebraska Medical Center, Omaha, Nebraska
Conditions: Parkinson's Disease, Sleep Fragmentation
Lu AF28996 in Participants With Parkinson's Disease (PD)
Recruiting
The purpose of this study is to investigate the safety of Lu AF28996, how well it is tolerated and what the body does to the drug in participants with Parkinson's disease.
Gender:
ALL
Ages:
Between 35 years and 85 years
Trial Updated:
05/07/2025
Locations: Neurology Consultants of Nebraska, Omaha, Nebraska
Conditions: Parkinson Disease
Novel DBS Stimulation Patterns for Treatment of Parkinson's Disease
Recruiting
This is an open-label, non-randomized, proof-of-concept comparison of clinical vs. research stimulation patterns in patients with Parkinson's disease (PD) being treated with Deep Brain Stimulation (DBS) through the Medtronic Percept PC DBS device. The investigators hypothesize that stimulation patterns designed to better target excessive synchrony in a patient-tailored manner may result in more efficient and effective therapy with fewer side effects. Medtronic 3rd-generation sensing implantable... Read More
Gender:
ALL
Ages:
Between 19 years and 80 years
Trial Updated:
07/26/2024
Locations: Unversity of Nebraska Medical Center, Omaha, Nebraska
Conditions: Parkinson's Disease