There are currently 585 clinical trials in Omaha, Nebraska looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Nebraska Medical Center, Creighton University Medical Center, Nebraska Methodist Hospital and Alegent Health Bergan Mercy Medical Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Oxygen-guided Supervised Exercise Therapy
NCT06003855
Recruiting
Peripheral artery disease (PAD) is a cardiovascular disease manifesting from systemic atherosclerosis, which blocks the leg arteries and results in insufficient blood flow to the lower extremities. Limb ischemia from PAD is the most common disorder treated within the vascular surgery service at the Omaha Veterans' Affairs Medical Center. PAD also accounts for one-third of the operations performed in the VA Medical Centers nationwide. This project aims to establish the feasibility and acceptabili... Read More
Gender:
ALL
Ages:
All
Trial Updated:
10/25/2024
Locations: Omaha VA Nebraska-Western Iowa Health Care System, Omaha, NE, Omaha, Nebraska
Conditions: Peripheral Artery Disease
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Targeted Transcranial Magnetic Stimulation to Improve Hippocampal-dependent Declarative Memory Abilities
NCT03574207
Recruiting
This is a pilot study of non-invasive transcranial magnetic stimulation (TMS) to improve memory in healthy adults. It will also examine treating memory deficits in older adults with amnestic mild cognitive impairment (aMCI), a condition that frequently precedes Alzheimer's disease (AD). The study will test whether a form of non-invasive brain stimulation repetitive transcranial magnetic stimulation (rTMS) can improve memory abilities in healthy young adults, healthy older adults, and older adult... Read More
Gender:
ALL
Ages:
19 years and above
Trial Updated:
10/21/2024
Locations: University of Nebraska Medical Center, Omaha, Nebraska
Conditions: Mild Cognitive Impairment, Memory Loss
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Impella RP Flex with Smart Assist
NCT06637644
Recruiting
To capture observational data of the Abiomed Impella RP Flex in a real-world setting.
Gender:
ALL
Ages:
All
Trial Updated:
10/09/2024
Locations: University of Nebraska Medical Center, Omaha, Nebraska
Conditions: Right Ventricular (RV) Dysfunction
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Comparison of Gait in Syndesmosis Injuries Treated With Screw Fixation vs Suture Button
NCT04972578
Recruiting
Injuries to the distal tibiofibular syndesmosis are common and occur in an estimated 25% of all rotational ankle fractures. Anatomic reduction of the syndesmosis has been associated with improved functional outcome as well as decreased rates of posttraumatic arthritis. Both screw fixation and suture fixation have become accepted standards of care for treatment of syndesmotic injuries. Recent literature would suggest trends favoring suture fixation over screw fixation with improved quality of syn... Read More
Gender:
ALL
Ages:
19 years and above
Trial Updated:
10/01/2024
Locations: Lauritzen Outpatient Center, Omaha, Nebraska +1 locations
Conditions: Acute Disruption of Ankle Syndesmosis
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High-dose Brachytherapy Boost With Stereostatic Body Radiation Therapy to Intermediate or Higher Risk Prostate Cancer
NCT05754580
Recruiting
The objective of this phase I/II trial is to prospectively evaluate the toxicity and therapeutic efficacy of Stereostatic Body Radiation Therapy (SBRT) to prostate and pelvic lymph nodes in combination with high-dose-rate (HDR) brachytherapy to the prostate in patients with localized unfavorable-intermediate risk or higher disease.
Gender:
MALE
Ages:
19 years and above
Trial Updated:
09/30/2024
Locations: University of Nebraska Medical Center, Omaha, Nebraska
Conditions: Prostatic Cancer
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Behavioral Economic & Staffing Strategies in the ICU
NCT06184945
Recruiting
The overarching goal of this study is to support the "real world" assessment of strategies used to foster adoption of several highly efficacious evidence-based practices in healthcare systems that provide care to critically ill adults with known health disparities. Investigators will specifically evaluate two discrete strategies grounded in behavioral economic and implementation science theory (i.e., real-time audit and feedback and registered nurse implementation facilitation) to increase adopt... Read More
Gender:
ALL
Ages:
19 years and above
Trial Updated:
09/30/2024
Locations: University of Nebraska Medical Center, Omaha, Nebraska
Conditions: Implementation Science, Delirium, Critical Illness, Mechanical Ventilation Complication, ICU Acquired Weakness, Pain
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Exoskeleton Variability Optimization
NCT04338815
Recruiting
The investigators will evaluate a potentially faster and more clinically feasible method to optimize exoskeletons in pilot tests in healthy in preparation for patients with peripheral artery disease.
Gender:
ALL
Ages:
Between 19 years and 85 years
Trial Updated:
09/25/2024
Locations: University of Nebraska Omaha, Omaha, Nebraska
Conditions: Peripheral Arterial Disease
Register for Updates
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASC61in Subjects With Advanced Solid Tumors
NCT05287399
Recruiting
This is a Phase 1, open-label, multicenter, single-arm, dose escalation study, designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary antitumor activity of single-agent ASC61(an orally bioavailable small-molecule inhibitor of PD-L1) in subjects with advanced solid tumors for whom no standard therapy is available.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/25/2024
Locations: Nebraska Cancer Specialists, Omaha, Nebraska
Conditions: Advanced Solid Tumors
Register for Updates
Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
NCT03827694
Recruiting
This study will establish a non-invasive diagnostic approach and evaluate clinical outcomes for children at high-risk for pulmonary invasive fungal infection (PIFI).
Gender:
ALL
Ages:
Between 120 days and 21 years
Trial Updated:
09/24/2024
Locations: Children's Omaha, Omaha, Nebraska
Conditions: Pulmonary Invasive Aspergillosis, Pulmonary Invasive Fungal Infections
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Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients
NCT05669833
Recruiting
The trial is an open-label randomized study that will examine whether switching to a selective IL23 inhibitor (guselkumab) is more effective than switching to a second TNFi (golimumab) among patients with PsA who have an inadequate response to a TNFi.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
09/23/2024
Locations: University of Nebraska Medical Center, Omaha, Nebraska
Conditions: Psoriatic Arthritis
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Skeletal Effects of Type 1 Diabetes on Low-Trauma Fracture Risk
NCT05701254
Recruiting
Patients with Type 1 Diabetes Mellitus (T1DM) have a higher risk of low-trauma (osteoporotic) fracture that is 7-12 times higher than non-diabetics. The bone density of people with Type 1 Diabetes is higher at the time of fracture than in non-diabetics. This suggests the presence of underlying bone tissue mechanical defects. The potential benefits to participants would be knowledge gained about their bone density and the results of laboratory tests. On a wider scale, there may be general benefit... Read More
Gender:
FEMALE
Ages:
50 years and above
Trial Updated:
09/23/2024
Locations: Creighton University Osteoporosis Research Center, Omaha, Nebraska
Conditions: Type 1 Diabetes, Osteopenia, Bone Loss, Fractures, Bone
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Consent for Use of Stored Patient Specimens for Future Testing
NCT00031408
Recruiting
The purpose of this study is to obtain informed consent to use stored human biological materials (HBM) (e.g., blood and other tissues) for future studies that may include genetic testing.
Gender:
ALL
Ages:
All
Trial Updated:
09/20/2024
Locations: Specialty Care Center CRS 1505, Omaha, Nebraska
Conditions: HIV Infections
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