The state of New Jersey currently has 10 active clinical trials seeking participants for Depression research studies. These trials are conducted in various cities, including New Brunswick, Hackensack, Newark and Morristown.
Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD
Recruiting
Efficacy, Safety, and Tolerability of two administrations of COMP360 in participants with treatment-resistant depression (TRD)
Gender:
All
Ages:
18 years and above
Trial Updated:
06/21/2024
Locations: Hassman Research Institute, Berlin, New Jersey +1 locations
Conditions: Treatment Resistant Depression
A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
Recruiting
Bipolar disorder is a severe chronic mood disorder that affects up to 4% of the adult population and 1.8% of the pediatric population in the United States. The treatment of the depressive episodes of bipolar disorder in the pediatric population has not been as widely studied as the treatment of depressive episodes in bipolar disorder in adults, therefore pharmacotherapeutic options are limited. Given the change in disease state and safety demonstrated in adults with depressive episodes associate... Read More
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
06/18/2024
Locations: Med Clinical Research Partners LLC /ID# 240773, Irvington, New Jersey +1 locations
Conditions: Depression, Bipolar I Disorder
BPL-003 Efficacy and Safety in Treatment Resistant Depression
Recruiting
This is a Phase 2 study randomized, quadruple masked, multi-center study designed to investigate the efficacy and safety of a single dose of BPL-003 combined with psychological support in patients with treatment resistant depression (TRD).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/29/2024
Locations: CenExel HRI, Berlin, New Jersey
Conditions: Treatment Resistant Depression
SilverCloud as a School-Based Intervention for Vulnerable Youth
Recruiting
The goal of this study is to test the efficacy and feasibility of a clinician-guided, app-based cognitive behavioral therapy (CBT) program, SilverCloud, as a school-based mental health intervention for vulnerable youth. An open trial of SilverCloud will be conducted to determine preliminary efficacy in this sample and inform program refinements by collecting outcome self-report assessments and conducting interviews on feasibility and acceptability. After the program and its implementation strate... Read More
Gender:
All
Ages:
Between 13 years and 22 years
Trial Updated:
04/04/2024
Locations: Rutgers University, New Brunswick, New Jersey
Conditions: Depression, Anxiety
Adapting BA for Minimally Verbal Autistic Adults
Recruiting
The present study aims to adapt and evaluate the feasibility of the BeatIt-2 behavioral activation intervention for people with intellectual disabilities and low mood to be implemented with minimally verbal autistic individuals.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/20/2024
Locations: Rutgers University - New Brunswick, Piscataway, New Jersey
Conditions: Autism, Depression, Autism Spectrum Disorder With Impaired Functional Language, Autism Spectrum Disorder
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
Recruiting
Objectives of this study are to determine whether active VNS Therapy treatment is superior to a no stimulation control in producing a reduction in baseline depressive symptom severity, based on multiple depression scale assessment tools at 12 months from randomization.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2024
Locations: Jersey Shore University Medical Center, Neptune, New Jersey
Conditions: Treatment Resistant Depression
Randomized, Double-Blind, Placebo-Controlled Trial of REL-1017 as Adjunctive Treatment for MDD
Recruiting
A Phase 3, randomized, double-blind, placebo-controlled, multicenter trial of REL-1017 in patients with major depressive disorder (MDD).
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/15/2024
Locations: Relmada Site, Toms River, New Jersey
Conditions: Major Depressive Disorder, Depression
A Study to Assess the Efficacy and Safety of REL-1017 as Adjunctive Treatment for Major Depressive Disorder (MDD)
Recruiting
This is an outpatient, 2-arm, Phase 3, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of REL-1017 once daily (QD) as an adjunctive treatment of Major Depressive Disorder. Study participants will continue to take their current antidepressant therapy in addition to the study drug or placebo for the duration of the treatment period.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/15/2024
Locations: Relmada Site, Princeton, New Jersey +1 locations
Conditions: Major Depressive Disorder, Depression
Transdiagnostic Individual Behavioral Activation and Exposure Therapy
Recruiting
The Overall Aim of the this project is to compare treatment outcomes and change in putative treatment mediators in Individual Behavioral Activation Therapy (IBAT) against two active psychological interventions (Coping Cat, PASCET) and a wait-list control. Participants will be 200 youth (ages 9-17) diagnosed with a principal anxiety or depression disorder and their caregivers.
Gender:
All
Ages:
Between 9 years and 17 years
Trial Updated:
11/15/2023
Locations: Youth Anxiety and Depression Clinic, Piscataway, New Jersey
Conditions: Anxiety Disorders, Depression
Comparing Targets of Expressive Writing
Recruiting
Expressive writing (Pennebaker & Beall, 1986) involves writing about one's deepest thoughts and feelings surrounding an emotional event. The current literature on the efficacy of expressive writing is mixed and warrants further investigation into how, when, and for whom expressive writing is an effective intervention. The goal of this study is to compare the efficacy of expressive writing interventions in young adults when people imagine that they're writing to themselves vs. a loved one. Partic... Read More
Gender:
All
Ages:
Between 18 years and 25 years
Trial Updated:
11/06/2023
Locations: Peretsman Scully Hall, Princeton, New Jersey
Conditions: Healthy, Anxiety, Depression