Comparing Targets of Expressive Writing
Recruiting
Expressive writing (Pennebaker & Beall, 1986) involves writing about one's deepest thoughts and feelings surrounding an emotional event. The current literature on the efficacy of expressive writing is mixed and warrants further investigation into how, when, and for whom expressive writing is an effective intervention. The goal of this study is to compare the efficacy of expressive writing interventions in young adults when people imagine that they're writing to themselves vs. a loved one. Partic... Read More
Gender:
All
Ages:
Between 18 years and 25 years
Trial Updated:
11/06/2023
Locations: Peretsman Scully Hall, Princeton, New Jersey
Conditions: Healthy, Anxiety, Depression
A Multiple Ascending Dose Trial of Emraclidine in Elderly Participants
Recruiting
The primary purpose of the study is to evaluate the safety and tolerability of multiple ascending doses of emraclidine administered orally to elderly participants.
Gender:
All
Ages:
Between 65 years and 85 years
Trial Updated:
10/11/2023
Locations: Marlton, New Jersey, Marlton, New Jersey
Conditions: Healthy Participants
Single Ascending Dose Study of NRS 033 in Healthy Volunteers
Recruiting
This is a phase 1, first in human, randomized, double-blind, placebo-controlled, single ascending dose (SAD) study in healthy adult male and female subjects 18 to 55 years of age, inclusive.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
08/28/2023
Locations: Frontage Clinical Research Center, Secaucus, New Jersey
Conditions: Healthy Volunteers
Bioavailability and Safety Study Comparing Two Dose Levels of AMZ001 and One Dose Level of Diclofenac Sodium 1% Gel in Healthy Participants
Recruiting
The goal of this clinical trial is to compare drug exposure from two different products (AMZ001 and Diclofenac Sodium 1% Gel) in healthy participants on Day 7 after repeated topical administrations for 7 days. Participants will receive, in a crossover design, three different treatments AMZ001 Low dose AMZ001 High dose Diclofenac Sodium 1% Gel Safety and tolerability of AMZ001 will be also investigated.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
07/27/2023
Locations: TKL Research, Fair Lawn, New Jersey
Conditions: Healthy
Study of Ciraparantag for Reversal of Anticoagulation Induced by Edoxaban, Apixaban or Rivaroxaban in Healthy Adults
Recruiting
A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of ciraparantag for reversal of anticoagulation induced by different anticoagulant drugs in generally healthy adults as measured primarily by an automated coagulometer device.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
07/18/2023
Locations: Frontage Clinical Services, Secaucus, New Jersey
Conditions: Healthy
Carbon Dioxide (CO2) and Cognitive Impairment
Recruiting
The purpose of the study is to better understand the biological mechanisms of carbon dioxide (CO2)-induced cognitive impairments.
Gender:
All
Ages:
Between 18 years and 30 years
Trial Updated:
07/17/2023
Locations: Rutgers - EOHSI, Piscataway, New Jersey
Conditions: Healthy
HomeStyles-2: Shaping HOME Environments and LifeSTYLES to Prevent Childhood Obesity
Recruiting
Parents are children's primary role models, are food and physical activity gatekeepers, and create the structure/lifestyle environment within the home. Thus, parents strongly influence children's weight-related behaviors and have the opportunity to cultivate a "culture of health" within the home. Yet, there continues to be a dearth of evidence-based obesity prevention intervention programs, especially for families with children aged 6 to 11 years, commonly called the middle childhood years. The... Read More
Gender:
All
Ages:
Between 24 years and 50 years
Trial Updated:
07/06/2023
Locations: Rutgers University, New Brunswick, New Jersey
Conditions: Healthy Lifestyle, Home Environment Related Disease, Cognitive Change, Child Behavior, Child Obesity, Parenting, Parents, Parent-Child Relations
A Study to Investigate The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JZP441 in Sleep-deprived Healthy Participants
Recruiting
This Phase 1, double-blind, randomized, placebo-controlled study will characterize the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of ascending nighttime doses of JZP441 in sleep-deprived healthy participants.
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
06/16/2023
Locations: Clinical Site 1, Eatontown, New Jersey
Conditions: Healthy Participants
Safety, Tolerability, and Pharmacokinetics Study of ATH-1020
Recruiting
This Phase 1 randomized, placebo-controlled, double-blinded, first-in-human study will evaluate safety, tolerability, and pharmacokinetics of single and multiple ascending doses of ATH-1020 in healthy young and elderly subjects.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
08/26/2022
Locations: Biotrial, Inc., Newark, New Jersey
Conditions: Healthy Volunteers
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of CB03-154 in Healthy Participants
Recruiting
CB03-154 is an investigational drug developed by Shanghai Zhimeng Biopharma Inc. for the treatment of Epilepsy.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
08/14/2022
Locations: Frontage Clinical Services, Inc., Secaucus, New Jersey
Conditions: Healthy Volunteers
Telerehabilitation Alzheimer's Disease Feasibility (TADF)
Recruiting
This is a pilot RCT with equal arms: experimental arm and (wait list) control arm. All participants will be in the early stage of Alzheimer's disease and on stable medication. They will all continue with this medication for their 6 months participation. Experimental group will add weekly training on the experimental device, 5 days a week for 8 weeks. Training will involve therapeutic games aimed primarily at the memory cognitive domain. All participants will receive weekly calls from clinical... Read More
Gender:
All
Ages:
Between 65 years and 85 years
Trial Updated:
04/26/2022
Locations: Rutgers, The State University of New Jersey, New Brunswick, New Jersey +1 locations
Conditions: Alzheimer Disease, Healthy Aging
A Study Investigating Lu AG22515 in Healthy Adults
Recruiting
The main goal of this study is to learn more about the safety of a drug called Lu AG22515. During the trial, healthy adult participants will receive a single dose of Lu AG22515 or a placebo (normal saline solution).
Gender:
All
Ages:
Between 19 years and 60 years
Trial Updated:
03/21/2022
Locations: Frontage Clinical Services, Inc., Secaucus, New Jersey
Conditions: Healthy Participants