SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
Recruiting
The purpose of this single-arm interventional study is to evaluate the long-term safety, efficacy, and durability of the Symplicity Spyral system in subjects treated with renal denervation. Additionally, long-term follow-up data will also be collected from eligible subjects previously treated in the SPYRAL PIVOTAL-SPYRAL HTN-OFF MED and SPYRAL HTN-ON MED studies.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/17/2023
Locations: Morristown Medical Center, Morristown, New Jersey
Conditions: Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular Hypertension
Recruiting
This is a multicenter, open-label, dose escalation (Cohort 1) to masked, randomized, parallel-group (Cohort 2) study to evaluate the safety and efficacy of AGN-193408 SR in participants with open-angle glaucoma or ocular hypertension
Gender:
All
Ages:
18 years and above
Trial Updated:
10/23/2023
Locations: Rutgers New Jersey Medical School Campus, Doctors Office Center /ID# 234365, Newark, New Jersey +1 locations
Conditions: Open-angle Glaucoma, Ocular Hypertension
18 Month Prospective Efficacy and Safety Study of Bimatoprost Intracameral Implant (DURYSTA)
Recruiting
Study to collect effectiveness and safety data after administration of a bimatoprost intracameral implant in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT).
Gender:
All
Ages:
18 years and above
Trial Updated:
10/06/2023
Locations: Eye Associates of North Jersey /ID# 244585, Dover, New Jersey +3 locations
Conditions: Open-angle Glaucoma, Ocular Hypertension
RADIANCE Continued Access Protocol
Recruiting
RADIANCE CAP is a non-randomized study designed to allow for continued access to ultrasound renal denervation therapy via the Paradise System, and to allow for the on-going collection of safety and effectiveness data in subjects with uncontrolled hypertension despite the prescription of antihypertensive medications.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
08/02/2023
Locations: Cardiovascular Associates of the Delaware Valley, Haddon Heights, New Jersey +1 locations
Conditions: Hypertension, Hypertension, Resistant to Conventional Therapy, Vascular Diseases, Cardiovascular Diseases
A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)
Recruiting
To assess efficacy, and safety of a single sustained release dose of the OTX-TIC drug product (2 travoprost dose strengths) in subjects with Open Angle Glaucoma (OAG) or Ocular Hypertension (OHT)
Gender:
All
Ages:
18 years and above
Trial Updated:
05/22/2023
Locations: Ocular Therapeutix, Inc., Dover, New Jersey
Conditions: Open Angle Glaucoma, Ocular Hypertension