Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome
Recruiting
The aim of this study is to assess whether IW-3300 is safe and works for the treatment of interstitial cystitis/bladder pain syndrome (IC/BPS). The main question the study aims to answer is whether IW-3300 helps bladder pain and other symptoms (for example, bladder burning, pressure and discomfort). Subjects will be assigned to receive either the study drug or placebo by chance.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
11/15/2023
Locations: Ironwood Research Center, Hackensack, New Jersey
Conditions: Interstitial Cystitis, Bladder Pain Syndrome
CEM-Plate and CEM-Cage First-In-Human Use Efficacy Study
Recruiting
The study is a prospective, first-in-human, multi-center, non-randomized, single-arm study to assess the safety and efficacy of the CEM-Cage used with the CEM-Plate in patients who are appropriate candidates for a 2-level anterior cervical discectomy and fusion (ACDF). Fifty patients will be enrolled in the study and, after undergoing a 2-level ACDF, will be evaluated at 4 weeks, 3 months, 6 months, 12 months, 18 months, and 24 months.
Gender:
All
Ages:
Between 22 years and 79 years
Trial Updated:
11/01/2023
Locations: IGEA, Union, New Jersey
Conditions: Neck Pain, Spondylosis, Spondylosis With Myelopathy, Spondylosis With Radiculopathy, Spondylosis With Radiculopathy Cervical Region, Intervertebral Disc Disorder Cervical
The Effect of Electroacupuncture on Nerve Pain Caused by Chemotherapy (Chemotherapy-Induced Peripheral Neuropathy)
Recruiting
Electroacupuncture (referred to as EA) may be an effective treatment for Chemotherapy-Induced Peripheral Neuropathy/CIPN pain. Acupuncture is a medical technique that involves insertion of very thin needles into specific areas on the body with the goal of promoting health and well-being. EA involves adding a very small amount of electricity through the acupuncture needles (electrical stimulation). Researchers have found that EA can increase the effects of regular acupuncture, and it is particula... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/16/2023
Locations: Memorial Sloan Kettering Basking Ridge (Limited protocol activities), Basking Ridge, New Jersey +2 locations
Conditions: Chemotherapy-induced Peripheral Neuropathy, Nerve Pain
A Study to Evaluate a Fixed Combination of Acetaminophen/Naproxen Sodium in Acute Postoperative Pain Following Bunionectomy
Recruiting
The purpose of this study is to evaluate effectiveness of a fixed combination of acetaminophen/naproxen sodium compared with placebo for reduction of pain when administered as multiple doses over a 48-hour period.
Gender:
All
Ages:
Between 16 years and 65 years
Trial Updated:
10/10/2023
Locations: Lotus Clinical Research, LLC, New Providence, New Jersey
Conditions: Pain
Study to Evaluate Neuromodulation Subject Experience With Contemporary Spinal Cord Stimulation (SCS) Modalities for Chronic Pain
Recruiting
Medtronic, Inc. is sponsoring the SENSE SCS clinical study, a prospective, multi-center, post-market, non-randomized, observational study with a hybrid decentralized model of execution, utilizing a mobile application for the collection of patient reported outcomes (PROs). The purpose of the study is to evaluate workflow of a mobile application for collection of PROs and to gather data on patient experience with spinal cord stimulation therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/09/2023
Locations: Garden State Pain and Orthopedics, Clifton, New Jersey
Conditions: Pain, Intractable, Pain, Chronic
Implementation and Effectiveness of Mindfulness Oriented Recovery Enhancement as an Adjunct to Methadone Treatment
Recruiting
This hybrid implementation-effectiveness trial will evaluate Mindfulness-Oriented Recovery Enhancement (MORE) for patients with opioid use disorder receiving methadone treatment (MT). The investigators will also assess barriers and facilitators to integrating MORE into methadone treatment, and evaluate the impact of a sustainable train-the-trainer model on provider burden, intervention fidelity, intervention engagement, and outcomes. Participants will be assigned to a higher intensity MORE imple... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/07/2023
Locations: Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey
Conditions: Opioid Use, Pain
Health Coaching for Chronic Multisymptom Illness
Recruiting
The National Academy of Medicine (NAM) labels chronic pain as one of the most extensive health care issues facing our society with "severe impacts on all aspects of the lives of its sufferers."1 Pain predominant chronic multisymptom illness (Pain-CMI, e.g., fibromyalgia) is a particularly debilitating and presumptive service connected condition for Veterans who deployed to the Gulf region. Health coaching is an appealing potential approach to improve the disability of Pain-CMI because it is pers... Read More
Gender:
All
Ages:
All
Trial Updated:
10/05/2023
Locations: East Orange Campus of the VA New Jersey Health Care System, East Orange, NJ, East Orange, New Jersey
Conditions: Pain Predominant Chronic Multisymptom Illness
The RESET Clinical Trial: SPRINT® Peripheral Nerve Stimulation for the Treatment of Back Pain
Recruiting
The purpose of this study is to compare standard of care treatments for back pain to electrical stimulation. Stimulation is delivering small amounts of electricity to the nerves in your low back. This study will use a device called the SPRINT Peripheral Nerve Stimulation (PNS) System. The device is cleared by the FDA for up to 60 days of use for the relief of chronic or acute pain (including back pain)
Gender:
All
Ages:
Between 21 years and 75 years
Trial Updated:
09/06/2023
Locations: Premier Pain Centers, Shrewsbury, New Jersey
Conditions: Low Back Pain, Back Pain
A Study of Stereotactic Radiosurgery (SRS) to Treat Pain in the Chest and/or Stomach Wall
Recruiting
The researchers are doing this study to find out whether stereotactic radiosurgery (SRS) is a safe, practical (feasible), and effective treatment for people with chronic TAWP. The researchers will test different doses of SRS to find the highest dose that causes few or mild side effects.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/02/2023
Locations: Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge, New Jersey +2 locations
Conditions: Thoracoabdominal Wall Pain, Secondary to Parietal Pleura or Parietal Peritoneum Disease
Prophylactic Analgesic and Antiemetic Regimen for Medical Abortion < 70 Days
Recruiting
Randomized trial which will aim to evaluate whether prophylactic use of ondansetron and ibuprofen will decrease side effects associated with medical abortion and increase patient satisfaction.
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
07/21/2023
Locations: Antonia Oladipo, Hackensack, New Jersey
Conditions: Nausea, Pain
Vitamin D to ENhance TraUma REcovery
Recruiting
The main objective of this study is to determine whether the administration of a single dose of Vitamin D in the Emergency Department following a motor vehicle collision can improve musculoskeletal pain severity as well as reduce musculoskeletal pain outcome disparity between Blacks and White following a motor vehicle collision. This randomized controlled trial is a pilot study to determine feasibility and potential efficacy (response to study drug, ability to reduce racial disparity in pain out... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/26/2023
Locations: Cooper University Hospital, Camden, New Jersey
Conditions: Musculoskeletal Pain
Focused Extracorporeal Shockwave Therapy for Knee Arthritis
Recruiting
Subchondral bone marrow lesions (BMLs) in knee osteoarthritis (OA) are strongly associated with presence and severity of knee pain, structural deterioration, disease progression with an increased risk of total knee arthroplasty. OA-related BMLs may regress or resolve within 30 months which could be associated with long lasting disability. It has been reported that BMLs persist in the majority of knee OA patients. Different treatment strategies have been proposed including rest and protected weig... Read More
Gender:
All
Ages:
Between 30 years and 80 years
Trial Updated:
05/03/2023
Locations: New Jersey Regenerative Institute, Cedar Knolls, New Jersey +1 locations
Conditions: Bone Marrow Edema, Knee Osteoarthritis, Knee Pain Chronic