There are currently 138 clinical trials in Newark, New Jersey looking for participants to engage in research studies. Trials are conducted at various facilities, including Newark Beth Israel Medical Center, Rutgers New Jersey Medical School, Saint Michael's Medical Center and University Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
sFOLFOXIRI in Advanced Gastroesophageal Cancer, (SAGE)
Recruiting
The primary objective is to determine the clinical efficacy of treatment regimen in terms of objective response rate (ORR). The secondary objectives is to determine the clinical efficacy of the study treatment in terms of progression free survival (PFS) and overall survival (OS). Additionally, to characterize the safety and toxicity profile of the study treatment as measured by the adverse event rates.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/21/2023
Locations: RWJBarnabas Health - Newark Beth Israel Medical Center, Newark, New Jersey
Conditions: Gastro-Intestinal Cancer
Neuropathy Walks (Cross-sectional)
Recruiting
Cross-sectional study is to explore the impact of painful neuropathy in the feet on function in persons living with HIV (PLHIV).
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
08/18/2023
Locations: Rutgers Physical Therapy Program, Newark, New Jersey
Conditions: HIV Infections
Effects of TENS and Mindfulness Meditation in Persons With HIV-related Neuropathy
Recruiting
This study is to explore the effects of transcutaneous nerve stimulation (TENS) and mindfulness meditation in persons living with HIV (PLHIV) and painful neuropathy in the feet.
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
08/18/2023
Locations: Rutgers Physical Therapy Program, Newark, New Jersey
Conditions: HIV Infections
Accuracy of Pediatric Emergency Medicine Providers in Diagnosing Hip Effusions Using Point of Care Ultrasound
Recruiting
The purpose of this study is to determine if pediatric emergency medicine providers can accurately diagnose a hip effusion using point-of-care ultrasound (POCUS) compared to radiology ultrasound (RADUS).
Gender:
All
Ages:
Between 1 month and 18 years
Trial Updated:
07/25/2023
Locations: Newark Beth Israel Medical Center, Newark, New Jersey
Conditions: Hip Effusion, Septic Arthritis, Transient Synovitis, Hip
Internet Assisted Career-Oriented Soft-skills Training for Transition Age Youth With Mental Health Conditions
Recruiting
The purpose of this study is to evaluate the effectiveness of an internet- assisted Career-Oriented Work-Related Soft-skills Training (iCareer) intervention, infused with cognitive behavioral therapy, targeting individuals ages 16-24 with mental health conditions, to improve employment outcomes. The overall objective is to help transition-age youth (TAY) with psychiatric disabilities achieve optimal employment outcomes as part of successful transition to adulthood. Findings will have implication... Read More
Gender:
All
Ages:
Between 16 years and 24 years
Trial Updated:
07/22/2023
Locations: Rutgers Univeristy, Newark- Office of Disability Services, Newark, New Jersey
Conditions: Mental Health Wellness 1, Mental Health Wellness 2, Occupational Problems
Using MASL to Combat Oral Cancer
Recruiting
This project will evaluate the expression of a receptor called podoplanin (PDPN) in cells from oral cancers and precancerous lesions. We will also determine how sensitive oral cancer cells are to a potential drug called Maackia amurensis seed lectin (MASL).
Gender:
All
Ages:
18 years and above
Trial Updated:
07/12/2023
Locations: New Jersey Medical School, Newark, New Jersey +2 locations
Conditions: Squamous Cell Carcinoma of Head and Neck
Virtual Cycling Environments for Persons With Parkinson Disease
Recruiting
This study asks three questions about Persons with Parkinson Disease that use a bicycle for exercise. 1. Does the use of virtual reality increase the intensity and and enjoyment of the experience compared to bicycling without virtual reality? 2. Does the way in which the bicycling (interval compared to continous) is performed affect the experience? 3. How does the way the virtual reality is delivered (with goggles or projected on a screen) affect the experience?
Gender:
All
Ages:
Between 45 years and 75 years
Trial Updated:
06/24/2023
Locations: School of Health Professions, Newark, New Jersey
Conditions: Parkinson Disease
Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study
Recruiting
This phase II trial studies how well lower-dose chemotherapy plus radiation (chemoradiation) therapy works in comparison to standard-dose chemoradiation in treating patients with early-stage anal cancer. Drugs used in chemotherapy, such as mitomycin, fluorouracil, and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high-energy x-rays to kill tumor cells... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/21/2023
Locations: Rutgers New Jersey Medical School, Newark, New Jersey
Conditions: Anal Basaloid Carcinoma, Anal Canal Cloacogenic Carcinoma, Anal Canal Squamous Cell Carcinoma, Anal Margin Squamous Cell Carcinoma, Stage I Anal Cancer AJCC v8, Stage IIA Anal Cancer AJCC v8
Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)
Recruiting
This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important for tumor cell growth and progression. Crizotinib may stop the growth of tumor cells by blocking the ALK protein from working. Crizotinib may be an effective treatment for patients with non-sma... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/20/2023
Locations: Newark Beth Israel Medical Center, Newark, New Jersey
Conditions: ALK Gene Rearrangement, ALK Gene Translocation, ALK Positive, Stage IB Non-Small Cell Lung Carcinoma AJCC v7, Stage II Non-Small Cell Lung Cancer AJCC v7, Stage IIA Non-Small Cell Lung Carcinoma AJCC v7, Stage IIB Non-Small Cell Lung Carcinoma AJCC v7, Stage IIIA Non-Small Cell Lung Cancer AJCC v7
A Prospective and Retrospective Observational Study of Multidrug-Resistant Patient Outcomes With and Without Ibalizumab
Recruiting
The virological efficacy of ibalizumab has been clearly demonstrated in multiple clinical trials. This study will expand ibalizumab's clinical data set and allow a better understanding of the virologic response durability on ARV regimens with or without ibalizumab in a heterogeneous real-world patient population. Additional data on the efficacy and safety of ibalizumab and its impact on patient reported outcomes will be captured until study end. Primary Objective: To evaluate the long-term eff... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/20/2023
Locations: Prime Healthcare Services - St Michael's Medical Center, Newark, New Jersey
Conditions: HIV Infections, Multi-Antiviral Resistance
Radiation Therapy Boost Before Surgery for the Treatment of Non-metastatic Breast Cancer
Recruiting
This phase II trial investigates the safety of delivering a part (boost) of radiation treatment before breast surgery in treating patients with breast cancer that has not spread to other places in the body (non-metastatic). Radiation therapy uses high energy photons/electrons to kill tumor cells and shrink tumors. Delivering a boost radiation treatment before surgery when doctors can still visualize the tumor on imaging may help to better target the tumor and decrease the volume of normal irradi... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/20/2023
Locations: Rutgers New Jersey Medical School, Newark, New Jersey +1 locations
Conditions: Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8, Invasive Breast Carcinoma, Non-Metastatic Breast Carcinoma, Prognostic Stage 0 Breast Cancer AJCC v8, Prognostic Stage I Breast Cancer AJCC v8, Prognostic Stage IA Breast Cancer AJCC v8, Prognostic Stage IB Breast Cancer AJCC v8, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage IIA Breast Cancer AJCC v8, Prognostic Stage IIB Breast Cancer AJCC v8, Prognostic Stage III Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage IIIB Breast Cancer AJCC v8, Prognostic Stage IIIC Breast Cancer AJCC v8
Modulating Goal-directed Navigation Using Noninvasive Brain Stimulation
Recruiting
Our specific aim is to examine the effects of TMS on spatial processing during goal-directed navigation. In these experiments the investigators will utilize a scalp-recorded brain oscillation called right posterior theta that is believed to index the sensitivity of the parahippocampal cortex to spatial context. Here the investigators will asked whether this electrophysiological signal can be modulated up or down using TMS while participants engage in virtual navigation tasks, and if so, whether... Read More
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
04/12/2023
Locations: Rutgers University - Newark, Newark, New Jersey
Conditions: Spatial Navigation