There are currently 138 clinical trials in Newark, New Jersey looking for participants to engage in research studies. Trials are conducted at various facilities, including Newark Beth Israel Medical Center, Rutgers New Jersey Medical School, Saint Michael's Medical Center and University Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization
NCT05064540
Recruiting
Prospective, randomized, multi-center study designed to evaluate the outcomes of commercially available contemporary EVAR in a real-world population. Patients will be randomized into two device cohorts and compared across the primary endpoints. Patients will be followed procedurally to discharge, at 1, 6, 12 months and annually through to 5 years (total follow-up commitment).
Gender:
All
Ages:
21 years and above
Trial Updated:
03/28/2024
Locations: Newark Beth Israel Medical Center, Newark, New Jersey
Conditions: AAA, AAA - Abdominal Aortic Aneurysm
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Reducing Pain From Wisdom Molar Extractions
NCT05335070
Recruiting
This is a pilot study evaluating the ability of the Temporo-masseteric Nerve Block local anesthetic injection (this was called the Twin Block earlier) to reduce pain experienced by individuals undergoing removal of lower third molar(s) under intravenous sedation. Study participants will be queried for pain experience and pain medications taken during the first post-operative week and will present for a follow-up visit on Day 8.
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
03/24/2024
Locations: The University Hospital- Dental Clinic, Newark, New Jersey
Conditions: Acute Pain
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Characterization of the Temporo-masseteric Nerve Block (TMNB) in Healthy Subjects
NCT05507164
Recruiting
The proposed pilot study is aimed at preliminary characterization of the TMNB injection in 20 healthy volunteers. Assessment of bite-force distribution and surface electromyographic activity of the temporalis and the masseter muscles, at rest and clench, before and after unilateral TMNB injection, will be the primary outcome measures. Post-injection assessments will be performed at 30 minutes, 2 hours, and 2 weeks after the injection. Participants will be surveyed regarding their experience rece... Read More
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
03/24/2024
Locations: Rutgers School of Dental Medicine, Newark, New Jersey
Conditions: Occlusion
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Evorpacept (ALX148) in Combination With Pembrolizumab in Patients With Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-03)
NCT04675294
Recruiting
A Phase 2 Study of evorpacept (ALX148) in Combination With pembrolizumab in Patients With Advanced Head and Neck Squamous Cell Carcinoma.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/21/2024
Locations: Rutgers Cancer Institute of New Jersey, Newark, New Jersey
Conditions: Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma
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Microbiotic Product to Promote Microbiome Health and Improve Chemotherapy Delivery
NCT05296681
Recruiting
This phase II trial tests whether NBT-NM108 works in reducing chemotherapy-induced diarrhea in patients with colon cancer that has spread to other places in the body (metastatic). Irinotecan is one of the most used medicine for colon cancer, but it leads to diarrhea in most patients receiving it and among some of them, severe diarrhea can occur. NBT-NM108 is a high dietary fiber formula that is developed based on research findings that have shown that high fiber diets can help maintain healthy b... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: The Cancer Center, Newark, New Jersey +1 locations
Conditions: Metastatic Colon Carcinoma, Stage IV Colon Cancer AJCC v8, Stage IVA Colon Cancer AJCC v8, Stage IVB Colon Cancer AJCC v8, Stage IVC Colon Cancer AJCC v8
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Search to Advance Limited Use of Opioids Pilot: Optimization of Non-Opioid Therapy With a Steroid
NCT06074263
Recruiting
To provide health care professionals, including dentists, with the best possible evidence for clinical decision making when deciding upon analgesics and use of corticosteroid for acute post-surgical pain management; a pilot double blind randomized clinical trial will be conducted to test the hypothesis that use of preemptive dose of corticosteroid will reduce the need for opioid rescue. The impacted 3rd molar extraction model will be used due to the predictable severity of the post-operative pai... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
03/18/2024
Locations: Rutgers School of Dental Medicine, Newark, New Jersey
Conditions: Pain Management
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Modulating Reward Learning Using Transcranial Magnetic Stimulation
NCT06323057
Recruiting
Our specific aim is to examine the effects of TMS on reward processing during goal-directed behavior. In these experiments the investigators will utilize a scalp-recorded brain oscillation called frontal midline theta that is believed to index the sensitivity of the cingulate cortex to reward feedback. Here the investigators will asked whether this electrophysiological signal can be modulated up or down using TMS while participants engage in decision making tasks, and if so, whether it would aff... Read More
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
03/14/2024
Locations: Rutgers University - Newark, Newark, New Jersey
Conditions: Reward Learning
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COMPASSION S3 Post-Approval Study
NCT04860765
Recruiting
This study will monitor device performance and outcomes of the SAPIEN 3 Transcatheter Heart Valve (THV) System in subjects with a dysfunctional right ventricular outflow tract (RVOT) conduit or previously implanted surgical valve in the pulmonic position with a clinical indication for intervention.
Gender:
All
Ages:
All
Trial Updated:
03/12/2024
Locations: Newark Beth Israel Medical Center, Newark, New Jersey
Conditions: Complex Congenital Heart Defect, Dysfunctional RVOT Conduit, Pulmonary Valve Insufficiency, Pulmonary Valve Degeneration, Pulmonary Valve; Obstruction
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Liver Transplantation in Intrahepatic Cholangiocarcinoma
NCT06140134
Recruiting
The aim of the current study is to determine the potential efficacy of liver transplantation in the form of patients' overall survival (OS) after neoadjuvant systemic therapy in patients with biologically responsive locally advanced non-metastatic intrahepatic cholangiocarcinoma (iCCA) in comparison to patients historically treated with chemotherapy alone.
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
03/08/2024
Locations: Rutgers New Jersey Medical School, Newark, New Jersey +1 locations
Conditions: Intrahepatic Cholangiocarcinoma, Cholangiocarcinoma, Intrahepatic
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Persistent Post-Concussion Symptoms With Convergence Insufficiency
NCT05262361
Recruiting
Our successful R01 discovered 1) the neural mechanistic difference between typically occurring convergence insufficiency (TYP-CI) and binocularly normal controls and 2) the underlying mechanism of office-based vergence and accommodative therapy (OBVAT) that is effective in remediating symptoms. Adolescent and young adult concussion is considered a substantial health problem in the United States where our team has shown that about half of patients with persistent post-concussion symptoms have con... Read More
Gender:
All
Ages:
Between 11 years and 35 years
Trial Updated:
03/08/2024
Locations: NJIT, Newark, New Jersey
Conditions: Persistent Post-concussive Symptoms, Convergence Insufficiency, Mild Traumatic Brain Injury, Concussion, Mild, Concussion; Eye
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Intravesical BCG vs GEMDOCE in NMIBC
NCT05538663
Recruiting
The study hypothesis is that BCG naïve non-muscle invasive bladder cancer (NMIBC) patients treated with intravesical Gemcitabine + Docetaxel (GEMDOCE) will result in a non-inferior event-free survival (EFS) compared to standard treatment with intravesical BCG. The purpose of this study is to test whether Gemcitabine + Docetaxel is a better or worse treatment than the usual BCG therapy approach. The primary objective of this study is to determine the event free survival (EFS) of BCG-naïve high gr... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/08/2024
Locations: Rutgers New Jersey Medical School, Newark, New Jersey
Conditions: Non-muscle-invasive Bladder Cancer
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Dismantling the U.S. Social Norm of the "Kids' Food" Archetype (REACH Project)
NCT06266533
Recruiting
This project is the first stage of a health promotion campaign to shift social norms about marketing and feeding children ultra-processed foods. Embedded within a longitudinal ethnographic study using photo-elicitation techniques, mothers of preschool-age children will be randomly assigned to arts-based or traditional education about ultra-processed food.
Gender:
Female
Ages:
Between 18 years and 85 years
Trial Updated:
03/06/2024
Locations: Leaguers Inc. Head Start, Newark, New Jersey
Conditions: Food Selection, Environmental Exposure
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