There are currently 133 clinical trials in Newark, New Jersey looking for participants to engage in research studies. Trials are conducted at various facilities, including Newark Beth Israel Medical Center, Rutgers New Jersey Medical School, Saint Michaels Medical Center and University Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Reducing Pain From Wisdom Molar Extractions
NCT05335070
Recruiting
This is a pilot study evaluating the ability of the Temporo-masseteric Nerve Block local anesthetic injection (this was called the Twin Block earlier) to reduce pain experienced by individuals undergoing removal of lower third molar(s) under intravenous sedation. Study participants will be queried for pain experience and pain medications taken during the first post-operative week and will present for a follow-up visit on Day 8.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
12/18/2024
Locations: The University Hospital- Dental Clinic, Newark, New Jersey
Conditions: Acute Pain
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Well-Mama Community Doula Navigator Study
NCT05179369
Recruiting
This study will develop and test an intervention, called the Well-Mama intervention, which includes the use of a checklist by Community Doula Navigators to support pregnant women. Participants will be randomized to either receive standard perinatal care or standard perinatal care plus the Well-Mama intervention.
Gender:
FEMALE
Ages:
Between 15 years and 49 years
Trial Updated:
12/10/2024
Locations: University Hospital, Newark, New Jersey
Conditions: Pregnancy Related
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Assessment of Combined CCM and ICD Device in HFrEF
NCT05855135
Recruiting
The goal of this clinical trial is to demonstrate that the OPTIMIZER® Integra CCM-D System (the "CCM-D System") can safely and effective convert induced ventricular fibrillation (VF) and spontaneous ventricular tachycardia and/or ventricular fibrillation (VT/VF) episodes in subjects with Stage C or D heart failure who remain symptomatic despite being on guideline-directed medical therapy (GDMT), are not indicated for cardiac resynchronization therapy (CRT), and have heart failure with reduced le... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: Rutgers New Jersey Medical School, Newark, New Jersey
Conditions: Heart Failure, Heart Failure With Reduced Ejection Fraction, Implantable Defibrillator User, CCM Therapy, Non-ischemic Cardiomyopathy, Ischemic Cardiomyopathy, Sudden Cardiac Arrest, Arrhythmias, Cardiac, Ventricular Tachycardia, Ventricular Fibrillation
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A Clinical Trial of STP0404 in Adults with HIV-1 Infection
NCT05869643
Recruiting
The purpose of this study is to evaluate the antiviral effect, safety, tolerability, and pharmacokinetics of STP0404 in adult participants living with Human Immunodeficiency Virus Type 1 (HIV-1) infection.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/27/2024
Locations: Saint Michael's Medical Center, Newark, New Jersey
Conditions: HIV-1-infection
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Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer
NCT06518837
Recruiting
This clinical trial aims to evaluate the effectiveness of tirzepatide in achieving a 5% or more body weight reduction in patients undergoing adjuvant treatment for hormone receptor-positive, HER2-negative (HR+/Her2-) breast cancer. The study will also assess the safety and tolerability of tirzepatide, its feasibility based on discontinuation rates, and completion of treatment. Secondary objectives include evaluating 3-year invasive disease-free survival (IDFS) and distant relapse-free survival (... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/27/2024
Locations: RWJBarnabas Health - Newark Beth Israel Medical Center, Newark, New Jersey
Conditions: Hormone Receptor-Positive Breast Cancer, HER2-Negative Breast Cancer
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Assessment of Early Radiation Oncology Involvement Alongside Standard Oncologic Care in the Managemet
NCT05351294
Recruiting
To determine if the experimental approach of early radiation oncology involvement alongside standard oncologic care will result in higher HRQL at 6 months compared to the control arm receiving standard oncologic care alone, based on the global subscale score of the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 questionnaire.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/26/2024
Locations: Malcolm David Mattes, MD, Newark, New Jersey +1 locations
Conditions: Radiation Therapy, Metastatic Cancer
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Identify the Optimal TMS Pulse Protocol to Modulate Reward Activity
NCT06695884
Recruiting
Our primary goal will be to identify the optimal pulse protocol by systematically measuring the efficacy of various theta burst stimulation and repetitive rTMS protocols to increase and decrease the reward positivity in dependent smokers. Our secondary objective will be to measure the protocols' effectiveness to increase decision-making capacity using the probabilistic selection task (PST). Our third objective will be to specifically assess whether the TMS targets has a differential impact on st... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
11/15/2024
Locations: Rutgers University - Newark, Newark, New Jersey
Conditions: Nicotine Use Disorder
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Pharmacokinetics, Pharmacodynamics and Safety of Epeleuton in Patients with Sickle Cell Disease
NCT05861453
Recruiting
To assess the pharmacokinetics, pharmacodynamics and safety of Epeleuton capsules in adult SCD patients who are aged ≥18 years.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: Newark Beth Israel Medical Center, Newark, New Jersey
Conditions: Sickle Cell Disease
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Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) in Prevention of HIV in Cisgender Women in the United States (HPTN 102)
NCT06101329
Recruiting
The goal of this clinical study is to look at how lenacapavir (LEN) passes through the body and to assess the safety of LEN and emtricitabine/tenofovir disoproxil fumarate (F/TDF) for prevention of HIV in the cisgender women in the US. The primary objectives of this study are: 1) to characterize the pharmacokinetics (PK) of LEN in United States (US) cisgender women; 2) to evaluate the safety of LEN and F/TDF for pre-exposure prophylaxis (PrEP) in US cisgender women; and 3) to evaluate the gener... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: Rutgers New Jesey Medical School - Clinical Research Center, Newark, New Jersey
Conditions: Pre-Exposure Prophylaxis of HIV Infection
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Characterization of the Temporo-masseteric Nerve Block (TMNB) in Healthy Subjects
NCT05507164
Recruiting
The proposed pilot study is aimed at preliminary characterization of the TMNB injection in 20 healthy volunteers. Assessment of bite-force distribution and surface electromyographic activity of the temporalis and the masseter muscles, at rest and clench, before and after unilateral TMNB injection, will be the primary outcome measures. Post-injection assessments will be performed at 30 minutes, 2 hours, and 2 weeks after the injection. Participants will be surveyed regarding their experience rece... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
11/12/2024
Locations: Rutgers School of Dental Medicine, Newark, New Jersey
Conditions: Occlusion
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Identify the Optimal TMS Target to Modulate Reward Activity
NCT05766254
Recruiting
Our primary goal will be to identify the optimal prefrontal-cingulate target by systematically measuring the efficacy of various image-based targeting techniques to increase the reward positivity using the 10-Hz TMS protocol in dependent smokers. Our secondary objective will be to measure the targets' effectiveness to increase decision-making capacity using the probabilistic selection task (PST). Our third objective will be to specifically assess whether the TMS targets has a differential impact... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
11/12/2024
Locations: Rutgers University - Newark, Newark, New Jersey
Conditions: Nicotine Use Disorder
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Internet Assisted Career-Oriented Soft-skills Training for Transition Age Youth with Mental Health Conditions
NCT05766280
Recruiting
The purpose of this study is to evaluate the effectiveness of an internet- assisted Career-Oriented Work-Related Soft-skills Training (iCareer) intervention, infused with cognitive behavioral therapy, targeting individuals ages 16-24 with mental health conditions, to improve employment outcomes. The overall objective is to help transition-age youth (TAY) with psychiatric disabilities achieve optimal employment outcomes as part of successful transition to adulthood. Findings will have implication... Read More
Gender:
ALL
Ages:
Between 16 years and 24 years
Trial Updated:
11/12/2024
Locations: Rutgers Univeristy, Newark- Office of Disability Services, Newark, New Jersey
Conditions: Mental Health Wellness 1, Mental Health Wellness 2, Occupational Problems
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