There are currently 8 active clinical trials seeking participants for Cardiac Disease research studies. The states with the highest number of trials for Cardiac Disease participants are New York, Ontario, California and North Carolina.
ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE
NCT05746559
Recruiting
The primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the clinical consequences of AKI (MAKE) at 90 days in adult participants with CKD who undergo non-emergent cardiac surgery with CPB.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
08/11/2025
Locations: Research Site, Tucson, Arizona +213 locations
Conditions: Chronic Kidney Disease, CKD, Cardiac Disease, Cardiopulmonary Bypass
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A Study of Electrocardiogram and Focused Cardiac Ultrasound for Enhanced Cardiac Disease Screening
NCT06891222
Recruiting
The purpose of this study is to evaluate and compare the effectiveness of active screening for SHD in asymptomatic outpatients referred for an ECG, using a combination of AI-ECG and FOCUS. Invites will be sent and participants enrolled electronically.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Cardiac Disease
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Fresh Autologous Whole Blood Transfusion After Cardiopulmonary Bypass
NCT03204357
Recruiting
Autologous blood transfused at the end of cardiopulmonary bypass will reduce total blood loss 24 hours after surgery and improve mitochondrial oxygen delivery measured by plasma succinate levels. The study design is a prospective randomized interventional trial of transfusion of fresh autologous whole blood versus standard of care expectant management of bleeding during elective cardiac surgery.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
11/18/2024
Locations: University of Colorado Hospital, Aurora, Colorado
Conditions: Cardiac Disease, Bleeding Postoperative
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Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)
NCT05055830
Recruiting
OPTIC is a prospective, open-label, non-randomized study of multiple medications administered to approximately 2000 children in the pediatric cardiac intensive care unit (PCICU) per routine clinical car by their treating provider. The purpose of this study is to characterize the PK of drugs routinely administered to children per standard of care using opportunistic and scavenged samples. The prescribing of drugs to children will not be part of this protocol. After the child/adult (\<21 years of... Read More
Gender:
ALL
Ages:
Between 0 months and 20 years
Trial Updated:
10/08/2024
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: Cardiac Disease, Critically Ill, Children, Adult
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Rectus Sheath Block in Cardiac Surgery
NCT05833048
Recruiting
This is a prospective, randomized study. The purpose of this study is to evaluate the effect of post-surgical pain control of a type of peripheral nerve block, Rectus Sheath Block. 1. Does the rectus sheath block decrease opioid consumption postoperatively after cardiac surgery? 2. Does the rectus sheath block decrease VAS pain scores postoperatively after cardiac surgery? Study participants will be assigned to receive either rectus sheath block or no block.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
08/06/2024
Locations: Mount Sinai Morningside Hospital Center, New York, New York
Conditions: Cardiac Disease, Postoperative Pain
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Cardiac Performance System Data Collection Study - Minnesota
NCT06149143
Recruiting
Non-significant risk device study to conduct evaluation of the performance of new device for monitoring of cardiac function (based on previous iterations 510(k) 173156)
Gender:
ALL
Ages:
22 years and above
Trial Updated:
04/15/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Cardiac Disease
Register for Updates
Cardiac Performance System Data Collection Study
NCT05866666
Recruiting
Non-significant risk device study to conduct evaluation of the performance of new device for monitoring of cardiac function (based on previous iterations 510(k) 173156)
Gender:
ALL
Ages:
22 years and above
Trial Updated:
11/20/2023
Locations: Orlando Health, Orlando, Florida
Conditions: Cardiac Disease
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Cardiovascular Structure and Function in the Mucopolysaccharidoses
NCT05063435
Recruiting
This study's investigators previously demonstrated the potential utility of non-invasive carotid ultrasonography to calculate carotid intima media thickness (cIMT) and stiffness (as measured by the three parameters, carotid cross-sectional distensibility \[cCSD\], carotid cross-sectional compliance \[cCSC\], and carotid incremental elastic modulus \[cIEM\]) in people with mucopolysaccharidoses (MPS). Investigators also studied arterial gene expression in animal models of MPS, and identified upr... Read More
Gender:
ALL
Ages:
All
Trial Updated:
08/28/2023
Locations: Children's Hospital of Orange County, Orange, California
Conditions: Mucopolysaccharidoses, Carotid Disease, Cardiac Disease, Inflammation
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