The state of New York currently has 17 active clinical trials seeking participants for Epilepsy research studies. These trials are conducted in various cities, including New York, Rochester, Bronx and Buffalo.
Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy
Recruiting
This is a multiple site, randomized, double blinded parallel-group controlled study. The purpose of this study is to evaluate efficacy, safety, and tolerability of repeated, daily sessions with the STARSTIM device, which delivers transcranial cathodal direct current stimulation (tDCS). Subjects will be treated with STARTSTIM or sham device for 10 sessions over a 2-week period. The subjects will be followed for an additional 10 weeks post treatment. Quality of Life questionnaires and adverse even... Read More
Gender:
All
Ages:
9 years and above
Trial Updated:
07/21/2023
Locations: University of Rochester, Rochester, New York
Conditions: Refractory Epilepsy, Focal Seizure, Seizures, Focal, Seizures, Epilepsy in Children, Epilepsy, Epilepsy, Tonic-Clonic
Telephone-Based Support Programs for People With Epilepsy
Recruiting
This is a two-arm randomized controlled trial to compare telephone-based depression self-management (UPLIFT) to telephone-based support groups (BOOST). A sample of 120 English- and Spanish-speaking people with epilepsy (PWE) with elevated depressive symptoms will be enrolled. Both interventions are 8-week programs delivered in one-hour weekly sessions to groups of about 6 participants. Changes in depressive symptoms, quality of life and seizures will be assessed over 12 months. The trial will al... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
07/06/2023
Locations: NYU Langone Health, New York, New York
Conditions: Epilepsy
Biology of Juvenile Myoclonic Epilepsy
Recruiting
The investigators are collecting genetic information through blood samples as well as clinical and EEG data from over 1000 people with Juvenile Myoclonic Epilepsy (JME) across the UK, Europe and North America. This study will draw on both existing and new samples from JME patients. These will be compared to anonymised data from samples for 2000 controls. The goal of this study is to find the genetic cause of JME. Finding the cause will help create better treatments for JME, as well as improve pa... Read More
Gender:
All
Ages:
Between 10 years and 40 years
Trial Updated:
05/24/2023
Locations: Mount Sinai-Beth Israel Medical Center, New York, New York +1 locations
Conditions: Juvenile Myoclonic Epilepsy
Electrophysiological Read-Out of Interoceptive Processing
Recruiting
Interoception, or sensation from inside the body, is involved in a variety of clinical symptoms, such as tics, compulsions and negative mood. This study uses invasive recordings of brain activity and brain stimulation to better understand basic neural mechanisms of interoception and related behaviors. Outcomes of this study provide critical tools for future investigation into clinical symptoms that emerge from abnormal interoception.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/03/2023
Locations: Mount Sinai West, New York, New York
Conditions: Drug-resistant Epilepsy
Perampanel Titration and Cognitive Effects
Recruiting
The objective of this study is to determine whether there are any differences in the cognitive abilities and/or behavioral response of normal healthy volunteers across different titration rates of perampanel.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
02/04/2023
Locations: New York University, New York, New York
Conditions: Epilepsy