There are currently 19 active clinical trials seeking participants for Ventricular Tachycardia research studies. The states with the highest number of trials for Ventricular Tachycardia participants are California, New York, Texas and Pennsylvania.
Effectiveness of CRD-4730 in Participants with Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
Recruiting
This is a Phase 2, multicenter, double-blind, sponsor unblinded, placebo-controlled, single-dose clinical study of CRD-4730 to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of CRD-4730 when administered as single oral doses to participants with Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT). The study will have 2 cohorts in which participants with CPVT will participate in a 3-period, randomized 2-sequence study. Each participant will receive 2... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
01/17/2025
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio +10 locations
Conditions: CPVT1, Heart Defects, Congenital, Heart Diseases, Ventricular Tachycardia
Trial in Arrhythmia Radioablation for Ventricular Tachycardia: Single Fraction vs Three Fractions
Recruiting
This is a research study that aims to understand if giving a lower dose of treatment all at once is as effective and safe as dividing it into three smaller doses for patients with a heart condition called refractory ventricular tachycardia (VT). These patients have not exhibited positive responses to conventional medications or procedures. This study aims to explore whether an alternative approach could yield more beneficial outcomes.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
02/18/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Ventricular Tachycardia
Venous Ethanol for Ventricular Tachycardia
Recruiting
Comparative effectiveness randomized clinical trial, comparing endocardial radiofrequency ablation alone vs radiofrequency ablation combined with venous ethanol in patients with ischemic ventricular tachycardia -Venous Ethanol for Left Ventricular Ischemic Ventricular Tachycardia -VELVET clinical trial
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
02/05/2025
Locations: Houston Methodist Hospital, Houston, Texas
Conditions: Ventricular Tachycardia, Ischemic Cardiomyopathy
Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy
Recruiting
Over the last decade, radiofrequency catheter ablation (RFCA) has become an established treatment for ventricular arrhythmias (VA). Due to the challenging nature of visualizing lesion formation in real time and ensuring an effective transmural lesion, different surrogate measures of lesion quality have been used. The Ablation Index (AI) is a variable incorporating power delivery in its formula and combining it with CF and time in a weighted equation which aims at allowing for a more precise esti... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/03/2025
Locations: Rush University Medical Center, Chicago, Illinois +3 locations
Conditions: Ventricular Tachycardia, Ischemic Cardiomyopathy
Defining the Risk of Ventricular Tachycardia in Genetic Forms of Early-onset Atrial Fibrillation
Recruiting
To use programmed ventricular stimulation at the time of AF ablation to define the prevalence and mechanism of inducible ventricular tachycardia (VT); pace-mapping to define the site of origin of ventricular arrhythmias; and voltage mapping to define low voltage scar substrate in the basal LV in patients with pathogenic TTN variants compared to genotype-negative controls.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/05/2025
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Ventricular Tachycardia, Atrial Fibrillation
Cardiac Radioablation for VT
Recruiting
The goal of this interventional study is to determine the minimum dose necessary for successful cardiac radioablation of refractory ventricular tachycardia (VT) and to study the utility of target volume definition using Delayed Enhancement Cardiac MRI (DE-CMR) .
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/02/2025
Locations: Corewell Health William Beaumont University Hospital, Royal Oak, Michigan
Conditions: Ventricular Tachycardia, Myocardial Infarction
Assessment of Combined CCM and ICD Device in HFrEF
Recruiting
The goal of this clinical trial is to demonstrate that the OPTIMIZER® Integra CCM-D System (the "CCM-D System") can safely and effective convert induced ventricular fibrillation (VF) and spontaneous ventricular tachycardia and/or ventricular fibrillation (VT/VF) episodes in subjects with Stage C or D heart failure who remain symptomatic despite being on guideline-directed medical therapy (GDMT), are not indicated for cardiac resynchronization therapy (CRT), and have heart failure with reduced le... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: CardioVascular Associates of Mesa, Mesa, Arizona +53 locations
Conditions: Heart Failure, Heart Failure With Reduced Ejection Fraction, Implantable Defibrillator User, CCM Therapy, Non-ischemic Cardiomyopathy, Ischemic Cardiomyopathy, Sudden Cardiac Arrest, Arrhythmias, Cardiac, Ventricular Tachycardia, Ventricular Fibrillation
Characterization of Cardiac Electrophysiological Effects of Autonomic Neuromodulation
Recruiting
Prospective cohort study evaluating the electrophysiologic and biochemical effects of stellate ganglion block in patients with ventricular tachycardia.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Ventricular Tachycardia
Ventricular Tachycardia Mechanisms
Recruiting
The purpose of this study is to understand why certain hearts have ventricular arrhythmias and help identify areas of the heart that cause arrhythmias. There is still a significant gap in understanding why ventricular arrhythmias occur. This study will examine the electrical properties of the heart tissue to understand how these arrhythmias occur, and hopefully identify areas that might lead to ventricular arrhythmias. The hope is that studying this might be able to improve outcomes during ventr... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: Emory University Hospital Midtown, Atlanta, Georgia +2 locations
Conditions: Ventricular Tachycardia
Defining the Risk of Ventricular Tachycardia in Genetic Cardiomyopathies
Recruiting
The goal of this observational study is to determine if electrophysiologic mapping and cardiac MRI can help identify patients that have genetic forms of cardiomyopathy that are at high risk for development of dangerous ventricular arrhythmias. The investigators aim to study: 1. the prevalence and mechanism of inducible ventricular tachycardia 2. pace-mapping to define the site of origin of ventricular arrhythmias 3. voltage mapping to define low voltage scar substrate in the basal LV to determ... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/15/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Atrial Fibrillation, Ventricular Tachycardia, Premature Ventricular Contraction
Randomized Assessment of TcMS for VT Storm
Recruiting
Three-arm randomized clinical trial comparing two strategies of TcMS to sham stimulation in patients with VT storm. The hypothesis of the study is that TcMS will reduce the burden of VT in the 24 hours after randomization compared to sham stimulation and that TcMS with theta burst stimulation (TBS) will be more effective at reducing VT burden than low frequency TcMS.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/27/2024
Locations: Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Ventricular Tachycardia
MANAGE-VT Registry - MANAGEment of Ventricular Tachycardia Outcomes Registry
Recruiting
Data collection registry for patients with ventricular tachycardia to help physicians give better care for patients clinically and procedurally.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/11/2024
Locations: Corvita Science Foundation, Chicago, Illinois
Conditions: Ventricular Tachycardia