Waldenström Macroglobulinemia Clinical Trials

A listing of 18 Waldenström Macroglobulinemia clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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There are currently 18 active clinical trials seeking participants for Waldenström Macroglobulinemia research studies. The states with the highest number of trials for Waldenström Macroglobulinemia participants are New York, Washington, Ohio and California.

Featured Trial

Healthy Participants Needed (Colonoscopy + Cancer Screening)

Recruiting

Earn $325 - $475 in electronic payment card compensation for your time and effort by participating in a clinical study to develop a blood test that may one day help screen for colon cancer. Take a quick quiz to see if you qualify.

Conditions:

Healthy

Healthy Volunteers

Healthy Subjects

Healthy Volunteer

Healthy Participants

Learn More

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Lose Weight with GLP-1 Medications

Recruiting

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Conditions:

Overweight

Overweight and Obesity

Obesity

Weight Loss

Morbid Obesity

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Featured Trial

Stroke Clinical Study

Recruiting

A clinical study for people that suffer with Stroke

Conditions:

Stroke

Learn More

Featured Trial

Chronic Kidney Disease (CKD) Clinical Study

Recruiting

A clinical study for people that suffer with Chronic Kidney Disease (CKD)

Conditions:

Chronic Kidney Disease (CKD)

Learn More

Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL)

NCT00923507

Recruiting

Background The development of new technologies now allow scientists to investigate the molecular basis and clinical manifestations of monoclonal B cell lymphocytosis (MBL), chronic lymphocytic leukemia(CLL)/small lymphocytic lymphoma (SLL), lymphoplasmacytic lymphoma (LPL)/Waldenstrom macroglobulinemia (WM), and splenic marginal zone lymphoma (SMZL). Applying these methods in a natural history study can help identify processes involved in disease progression, and possibly lead to the discovery... Read More

Gender:

ALL

Ages:

Between 18 years and 110 years

Trial Updated:

08/21/2025

Locations: National Institutes of Health Clinical Center, Bethesda, Maryland

Conditions: Waldenstrom Macroglobulinemia, Lymphoplasmacytic Lymphoma, Monoclonal B-Cell Lymphocytosis, Small Lymphocytic Lymphoma, CLL (Chronic Lymphocytic Leukemia)

Learn More ›

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

NCT05006716

Recruiting

Study consists of two main parts to explore BGB-16673 recommended dosing, a Phase 1 monotherapy dose finding comprised of monotherapy dose escalation and monotherapy safety expansion of selected doses, and a Phase 2 (expansion cohorts)

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/19/2025

Locations: University of Alabama At Birmingham Hospital, Birmingham, Alabama +116 locations

University of Alabama At Birmingham Hospital, Birmingham, Alabama

Western Regional Medical Center, Llc, Goodyear, Arizona

Mayo Clinic Phoenix, Phoenix, Arizona

Honor Health Research Institute, Scottsdale, Arizona

University of Arizona Cancer Center, Tucson, Arizona

University of California San Diego (Ucsd) Moores Cancer Center, La Jolla, California

Stanford Medicine, Palo Alto, California

UCLA Santa Monica Cancer Care, Santa Monica, California

Uchealth North, Fort Collins, Colorado

Mayo Clinic Jacksonville, Jacksonville, Florida

Mount Sinai Comprehensive Cancer Center, Miami Beach, Florida

Tampa General Hospital Cancer Institute, Tampa, Florida

Augusta University, Augusta, Georgia

Southeastern Regional Medical Center, Newnan, Georgia

Midwestern Regional Medical Center, Zion, Illinois

University of Iowa Hospitals and Clinics, Iowa City, Iowa

Norton Cancer Institute Pavilion, Louisville, Kentucky

Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana

American Oncology Partners of Maryland Pa, Bethesda, Maryland

Dana Farber Cancer Institute, Boston, Massachusetts

Karmanos Cancer Institute, Detroit, Michigan

Mayo Clinic Rochester, Rochester, Minnesota

Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada

Roswell Park Comprehensive Cancer Center, Buffalo, New York

Columbia University Medical Center, New York, New York

Weill Cornell Medical College Newyork Presbyterian Hospital, New York, New York

Memorial Sloan Kettering Cancer Center Mskcc, New York, New York

Tennesse Oncology Chattanooga, Chattanooga, Tennessee

Tennessee Oncology, Pllc Nashville, Nashville, Tennessee

Md Anderson Cancer Center, Houston, Texas

Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia

Fred Hutchinson Cancer Research Center, Seattle, Washington

Concord Repatriation General Hospital, Concord, New South Wales

Calvary Mater Newcastle, Waratah, New South Wales

Princess Alexandra Hospital, Woolloongabba, Queensland

St Vincents Hospital Melbourne, Fitzroy, Victoria

Peninsula Private Hospital, Frankston, Victoria

Austin Health, Heidelberg, Victoria

Peter Maccallum Cancer Centre, Melbourne, Victoria

The Alfred Hospital, Melbourne, Victoria

Linear Clinical Research, Nedlands, Western Australia

Perth Blood Institute, West Perth, Western Australia

Hospital Sirio Libanes Brasilia, Brasilia, Not set

Instituto de Pesquisa Em Saude Da Universidade de Caxias Do Sul, Caxias do Sul, Not set

Hospital Erasto Gaertner, Curitiba, Not set

Centro Gaucho Integrado de Oncologia Hospital Mae de Deus, Porto Alegre, Not set

Hospital Ernesto Dornelles, Porto Alegre, Not set

Real E Benemerita Associacao Portuguesa de Sao Paulo, Sao Paulo, Not set

Hospital Alemao Oswaldo Cruz, Sao Paulo, Not set

Hospital Nove de Julho Dasa, Sao Paulo, Not set

Instituto Dor de Pesquisa E Ensino Sao Paulo, Sao Paulo, Not set

Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein, Sao Paulo, Not set

Hospital Santa Rita de Cassia Afecc, Vitoria, Not set

Cross Cancer Institute, Edmonton, Alberta

British Columbia Cancer Agency the Vancouver Centre, Vancouver, British Columbia

Princess Margaret Cancer Centre, Toronto, Ontario

Arthur Je Child Comprehensive Cancer Centre, Calgary, Not set

Chu de Quebec Universite Laval, Hopital de Lenfant Jesus, Centre Integre de Cancerologie (Cic), Quebec, Not set

Centre de Lutte Contre Le Cancer Institut Bergonie, Bordeaux, Not set

Hopital Estaing, Clermontferrand, Not set

Chu Henri Mondor, Creteil, Not set

Hopital Claude Huriez Chu Lille, Lille, Not set

Centre Leon Berard, Lyon Cedex, Not set

Institut Paoli Calmettes, Marseille, Not set

Chu Montpellier Hopital Saint Eloi, Montpellier, Not set

Hopital de La Pitie Salpetriere, Paris, Not set

Centre Henri Becquerel, Rouen Cedex, Not set

Arensia Exploratory Medicine Llc, Tbilisi, Not set

Universitatsklinikum Carl Gustav Carus An Der Technischen Universitat Dresden, Dresden, Not set

Uniklinik Koeln (Aoer), Koln, Not set

Universitares Krebszentrum Leipzig, Leipzig, Not set

Universitaetsklinikum Schleswig Holstein Campus Luebeck, Luebeck, Not set

Klinikum Johannes Gutenberg Universitaet Mainz, Mainz, Not set

Klinikum Grosshadern Ludwig Maximilians Universitat Munchen, Munchen, Not set

Universitaetsklinikum Ulm, Ulm, Not set

Policlinico Sorsola Malpighi, Aou Di Bologna, Bologna, Not set

Ospedale San Raffaele, Milano, Not set

Istituto Europeo Di Oncologia, Milano, Not set

Niguarda Cancer Center Division of Hematology, Milano, Not set

Fondazione Policlinico Universitario Agostino Gemelli, Roma, Not set

Centroricerche Cliniche Di Verona Srl, Verona, Not set

Aichi Cancer Center Hospital Clinical Oncology, Nagoya, Aichi

Chiba Cancer Center, Chibashi, Chiba

National Cancer Center Hospital East, Kashiwa, Chiba

Cancer Institute Hospital of Jfcr, Kotoku, Tokyo

Yokohama Municipal Citizens Hospital, YokohamaShi, Not set

Inje University Busan Paik Hospital, BusanjinGu, Busan Gwang'yeogsi

Pusan National University Hospital, SeoGu, Busan Gwang'yeogsi

Samsung Medical Center, GangnamGu, Seoul Teugbyeolsi

The Catholic University of Korea, Seoul St Marys Hospital, SeochoGu, Seoul Teugbyeolsi

Severance Hospital Yonsei University Health System, SeodaemunGu, Seoul Teugbyeolsi

Seoul National University Hospital, Seoul, Seoul Teugbyeolsi

Asan Medical Center, SongpaGu, Seoul Teugbyeolsi

The Institute of Oncology, Arensia Exploratory Medicine, Chisinau, Not set

Hospital Universitario Vall Dhebron, Barcelona, Not set

Hospital de La Santa Creu I Sant Pau, Barcelona, Not set

Hospital General Universitario Gregorio Maranon, Madrid, Not set

Md Anderson Cancer Center Madrid Spain, Madrid, Not set

Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set

Hospital Universitario La Paz, Madrid, Not set

Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Not set

Hospital Clinico Universitario de Valencia, Valencia, Not set

Sahlgrenska University Hospital Hematology, Goteborg, Not set

Karolinska Universitetssjukhuset Solna, Stockholm, Not set

Uppsala Akademiska Sjukhus, Uppsala, Not set

Ankara University, Abidinpaa, Not set

Dr Abdurrahman Yurtaslan Research and Training Hospital, Ankara, Not set

Dokuz Eylul University, Balcova, Not set

Erciyes University, Kayseri, Not set

Sakarya Training and Research Hospital, Sakarya, Not set

Ondokuz Mayis University, Samsun, Not set

Edinburgh Cancer Centre, Edinburgh, Not set

Churchill Hospital Oxford University Hospital Nhs Trust, Headington, Not set

St Jamess University Hospital, Leeds, Not set

Freeman Hospital, NewCastle Upon Tyne, Not set

Nottingham University Hospitals Nhs Trust, Nottingham, Not set

Derriford Hospital, Plymouth, Not set

Conditions: B-cell Malignancy, Marginal Zone Lymphoma, Follicular Lymphoma, Non-hodgkin Lymphoma, Waldenström Macroglobulinemia, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Mantle Cell Lymphoma, Diffuse Large B Cell Lymphoma

Learn More ›

A Long-term Extension Study of PCI-32765 (Ibrutinib)

NCT01804686

Recruiting

The purpose of this study is to collect long-term safety and efficacy data for participants treated with ibrutinib and to provide ongoing access to ibrutinib for participants who are currently enrolled in ibrutinib studies that have been completed according to the parent protocol, are actively receiving treatment with ibrutinib, and who continue to benefit from ibrutinib treatment.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/15/2025

Locations: City of Hope Cancer Center, Duarte, California +173 locations

City of Hope Cancer Center, Duarte, California

University of California San Diego Medical Center, La Jolla, California

University of California Los Angeles, Los Angeles, California

St. Joseph Hospital Center for Cancer Prevention and Treatment, Orange, California

Stanford University Medical Center, Stanford, California

Stanford University, Stanford, California

Norwalk Medical Group, Norwalk, Connecticut

Northwest Georgia Oncology Centers PC, Marietta, Georgia

Northwestern University Hospital, Chicago, Illinois

Indiana University, Goshen, Indiana

Kansas University Medical Center, Westwood, Kansas

Louisville Oncology Suburban - Norton Cancer Institute, Louisville, Kentucky

Dana Farber Cancer Center, Boston, Massachusetts

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan

Battle Creek Health Systm, Battle Creek, Michigan

Karmanos Cancer Institute - Wayne State University, Detroit, Michigan

Washington University, Saint Louis, Missouri

Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire

Hackensack University Medical Center, Hackensack, New Jersey

Weill Medical College of Cornell University, New York, New York

Memorial Sloan-Kettering Cancer Center, New York, New York

Southeastern Medical Oncology Center, Goldsboro, North Carolina

The Ohio State University- James Cancer Hospital, Columbus, Ohio

Willamette Valley Cancer Center, Eugene, Oregon

Kaiser Permanente, Portland, Oregon

University of Pennsylvania Medical Center, Philadelphia, Pennsylvania

Avera Medical Group, Sioux Falls, South Dakota

MD Anderson Cancer Center - University of Texas, Houston, Texas

University of Virginia, Charlottesville, Virginia

University of Washington, Seattle, Washington

West Virginia University, Morgantown, West Virginia

University of Wisconsin Carbone Cancer Center - Wisconsin Institute for Medical Research, Madison, Wisconsin

CEMIC Saavedra, Ciudad Autonoma Buenos Aires, Not set

Fundaleu, Ciudad de Buenos Aires, Not set

Royal Adelaide Hospital, Adelaide, Not set

John Fawkner Cancer Trial Centre, Coburg, Not set

Concord Hospital, Concord, Not set

Austin Health, Heidelberg, Not set

Peter MacCallum Cancer Institute, Melbourne, Not set

Royal Perth Hospital, Perth, Not set

Alfred Hospital, Prahran, Not set

Adventist Health Care Limited trading as San Clinical Trials Unit, Wahroonga, Not set

UZA, Antwerp, Not set

A.Z. Sint Jan, Brugge, Not set

UCL - Saint Luc, Brussels, Not set

UZ Gent - departement oncologie, Gent, Not set

UZ Leuven Gasthuisberg, Leuven, Not set

UCL Mont-Godinne, Yvoir, Not set

Ministerio da Saude Instituto Nacional do Cancer, Rio De Janeiro, Not set

Santa Casa da Misericórdia da Bahia - Hospital Santa Isabel, Salvador, Not set

Instituto de Ensino e Pesquisa São Lucas, Sao Paulo, Not set

Jewish General Hospital, Montreal, Quebec

Peking University People s Hospital, Beijing, Not set

Peking University Third Hospital, Beijing, Not set

Peking University First Hospital, Beijing, Not set

West China Hospital Sichuan University, Chengdu, Not set

Fujian Medical University, Fuzhou, Not set

Sun Yat-sen University Cancer Hospital, Guangzhou, Not set

Zhejiang University First Hospital, Hangzhou, Not set

Ruijin Hospital, Shanghai, Not set

Tangdu hospital the Fourth Military Medical, Shanxi, Not set

The First Affliated Hospital of Soochow University, Suzhou, Not set

The Institute of Hematological disease, Tianjin, Not set

Wuhan Union Hospital, Wuhan, Not set

Fundacion Santa Fe, Bogota, Not set

Fundacion Oftalmologica de Santander - FOSCAL, Floridablanca, Not set

Fakultni nemocnice Brno, Interni hematologicka a onkologicka klinika, Brno, Not set

Fakultni nemocnice Kralovske Vinohrady - Interni hematologicka klinika, Praha 10, Not set

Vseobecna fakultni nemocnice v Praze - I. interni klinika - klinika hematologie, Praha 2, Not set

Hopital Henri Mondor, Creteil, Not set

Hôpital E. Muller, Mulhouse, Not set

Hopital Necker Enfants Malades, Paris cedex 15, Not set

HOPITAL SAINT LOUIS - Hematology / Oncology, Paris, Not set

Hopital Haut Leveque Service Maladie Du Sang, Pessac, Not set

CH LYON SUD - Hematology, Pierre Benite, Not set

CHU de Tours, Tours, Not set

Vivantes Klinikum Spandau-Klinik f. Innere Medizin Hämatologie/Onkologie/Gastroenterologie - Germany, Berlin, Not set

Universitätsklinikum Carl Gustav Carus; Med. Klinik und Poliklinik I - Hämatologische Ambulanz, Haus, Dresden, Not set

Universitätsklinikum Essen; Klinik f. Hämatologie- Germany, Essen, Not set

Justus-Liebig-Universitaet - Medizinische Klinik IV, Haematologie, Gießen, Not set

Universitätsklinikum Heidelberg Med. Klinik IV, Heidelberg, Not set

Universitätsklinikum des Saarlandes, Homburg/Saar, Not set

Gemeinschaftspraxis Dres. Uhle/Müller/Kröning/Jentsch-Ullrich - Germany, Magdeburg, Not set

OnkoNet Marburg GmbH, Marburg, Not set

Universitätsklinikum für Innere Med. III_Hämatologie, Onkologie...- Germany, Ulm, Not set

Laiko General Hospital - 1st department of Internal Medicine, Athens, Not set

G Papanikolaou Hospital of Thessaloniki, Thessalonikis, Not set

Semmelweis Egyetem, I. Belgyogyaszati Klinika, Budapest N/a, Not set

Szegedi Tudomanyegyetem II. Belgyogyaszati Klinika, Szeged, Not set

St James's Hospital, Dublin, Not set

Haemek Medical Center, Afula, Not set

Hillel Yaffe Medical Center - Oncology, Hadera, Not set

Rambam Health Care Campus, Haifa, Not set

Rabin Medical Center Beilinson Campus, Petah Tikva, Not set

Sheba Medical Center, Ramat-Gan, Not set

Tel Aviv Sourasky Medical Center, Tel Aviv, Not set

ASST Grande Ospedale Metropolitano Niguarda, Milano, Not set

DIPARTIMENTO DI BIOTECNOLOGIE CELLULARI ED EMATOLOGIA - UNIVERSITà ''LA SAPIENZA'', Roma, Not set

A.O.Citta della Salute e della Scienza di Torino, Torino, Not set

Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Bunkyo ku, Not set

Hiroshima University Hospital, Hiroshima shi, Not set

Hokkaido University Hospital, Sapporo-shi, Not set

National Cancer Center, Goyang-Si, Not set

The Catholic University of Korea Seoul St Mary s Hospital, Seoul, Not set

Oaxaca Site Management Organization S.C., Oaxaca, Not set

VU medisch centrum - Afd.Interne - INT, Amsterdam, Not set

Szpital Specjalistyczny w Brzozowie Podkarpacki Osrodek Onkologiczny im Ks B Markiewicza, Brzozow, Not set

Samodzielny Publiczny Zaklad Opieki Zdrowotnej Zespol Szpitali Miejskich, Chorzow, Not set

Uniwersyteckie Centrum Kliniczne, Gdansk, Not set

Pratia MCM Krakow, Krakow, Not set

Oddzial Hematologii, Opole, Not set

Wojewodzki Szpital Specjalistyczny im. Janusza Korczaka, Slupsk, Not set

Katedra I Klinika Hematologii Nowotworow Krwi I Transplantacji Szpiku, Wroclaw, Not set

Instituto Portugues de Oncologia, Lisboa, Not set

Hospital De Santa Maria, Lisbon, Not set

Instituto Portugues de Oncologia, Porto, Not set

Auxilio Mutuo Cancer Center, San Juan, Not set

Arkhangelsk Regional Clinical Hospital, Arkhangelsk, Not set

Chelyabinsk Regiona Onc. Center, Chelyabinsk, Not set

Emergency Hospital of Dzerzhinsk, Dzerzhinsk, Not set

Cancer Research Center, Moscow N/a, Not set

S.P. Botkin Moscow City Clinical Hospital, Moscow, Not set

Regional Clinical Hospital n.a.Semashko, Nizhni Novgorod, Not set

Medical Scientific Radiology - Center, Obninsk, Not set

Perm Medical Sanitary Unit#1, Perm, Not set

Republican Hospital named by V.A.Baranova, Petrozavodsk, Not set

Rostov Research Institute of Oncology, Rostov-Na-Donu, Not set

Ryazan Regional Clinical Hospital, Ryazan, Not set

Leningrad region clinical hospital, Saint, Not set

Samara Region Clinical Hospital, Samara, Not set

Federal Center of Heart, Blood and Endocrinology, Sankt-Peterburg, Not set

Oncological dispensary #2, Sochi, Not set

City Clinical Oncology Dispensary, St. Petersburg, Not set

Clinical Research Institute of Hematology and Transfusiology, St.-Petersburg, Not set

Oncology Dispensary of Komi Republic, Syktyvkar, Not set

Hospital Vall d'Hebron, Barcelona N/a, Not set

Inst. Cat. Doncologia-H Duran I Reynals, L'hospitalet De Llobregat, Not set

Hosp. Univ. de La Princesa, Madrid, Not set

Hosp. Gral. Univ. Gregorio Maranon, Madrid, Not set

Hosp. Univ. Infanta Leonor, Madrid, Not set

Fundacion Jimenez Diaz, Madrid, Not set

Clinica Universitaria de Navarra, Pamplona N/a, Not set

Hospital Clinico Universitario Salamanca, Salamanca, Not set

Sahlgrenska University hospital, Hematology Dept, Göteborg, Not set

Skanes universitetssjukhus, Lund, Not set

Karolinska Universitetssjukhuset Solna, Centrum för Hematologi, Stockholm, Stockholm, Not set

Changhua Cristian Hospital, Changhua County, Not set

Ankara University, Ankara, Not set

American Hospital, Istanbul, Not set

Istanbul University, Istanbul, Not set

Dokuz Eylul Universitesi Tip Fakultesi, Izmir, Not set

Erciyes University, Kayseri, Not set

Communal Nonprofit Enterprise 'Cherkasy Regional Oncology Dispensary Of Cherkasy Regional Council', Cherkasy, Not set

Dnepropetrovsk City Clinical Hospital #4, Regional Hematology Center, Dnepropetrovsk, Not set

SI Grigoriev Institute for Medical Radiology National Academy of Medical Science of Ukraine, Kharkiv, Not set

Khmelnitskiy Regional Hospital, Hematology Department, Khmelnitskiy, Not set

State Institution Scientific Center for Radiation Medicine Academy of Medical Sciences of Ukraine, Kiev, Not set

Institute of Blood Pathology and Transfusion Medicine of AMS of Ukraine, Lviv, Not set

Vinnytsya Regional Clinical Hospital named after M.I.Pirogov, Vinnitsa, Not set

University Hospitals Birmingham NHS Trust,, Birmingham, Not set

Royal Bournemouth Hospital, Bournemouth, Not set

Colchester Hospital University NHS, Colchester, Not set

Beatson West Of Scotland Cancer Centre, Glasgow, Not set

St James's Institute of Oncology, Leeds, Not set

Leicester Royal Infirmary - Haematology, Leicester, Not set

St Bartholomew's Hospital - Dept of Haematology, London, Not set

University College London Hospitals NHSFT, London, Not set

Kings College Hospital, London, Not set

Christie Hospital, Manchester, Not set

Nottingham University Hospitals NHS Trust, Nottingham, Not set

Derriford Hospital, Plymouth, Not set

Royal Hallamshire Hospital, Sheffield, Not set

Southampton General Hospital, Southampton, Not set

Royal Marsden Hospital (Sutton), Sutton, Not set

Conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Mantle Cell Lymphoma, Follicular Lymphoma, Diffuse Large B-cell Lymphoma, Waldenstrom Macroglobulinemia, Chronic Graft Versus Host Disease

Learn More ›

Observational Study Evaluating the Efficacy and Safety of Zanubrutinib in Participants With Waldenström Macroglobulinemia

NCT05640102

Recruiting

This is a hybrid (retrospective and prospective) non-interventional registry study to further describe the clinical profile of zanubrutinib in Waldenström macroglobulinemia (WM) participants with and without specific mutations and from racial and ethnic minority groups. Data collected from this registry study will be used to better understand the clinical benefit and safety of zanubrutinib for the treatment of participants in these populations.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/05/2025

Locations: Clearview Cancer Institute, Huntsville, Alabama +10 locations

Conditions: Waldenstrom Macroglobulinemia

Learn More ›

AutologousCD22 Chimeric Antigen Receptor (CAR)T Cells in w/Recurrent/Refractory B Cell Lymphomas

NCT06340737

Recruiting

This is a non-randomized clinical trial to evaluate the safety and efficacy of CD22CART administered after lymphodepleting chemotherapy in adults with relapsed / refractory B Cell Lymphomas. All evaluable participants will be followed for overall survival (OS), progression free survival (PFS), and duration of response (DOR). An evaluable participant is one who completes leukapheresis, lymphodepleting chemotherapy and CART infusion.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/04/2025

Locations: Stanford University, Palo Alto, California

Conditions: Follicular Lymphoma, Mantle Cell Lymphoma, Hairy Cell Leukemia, Lymphoplasmacytic Lymphoma, Burkitt Lymphoma, Marginal Zone Lymphoma, Waldenstrom Macroglobulinemia, Large B-cell Lymphoma

Learn More ›

AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

NCT05602363

Recruiting

This is an open-label, multi-center Phase 1b clinical study of oral AS-1763 (docirbrutinib) in patients with CLL/SLL or B-cell NHL who have failed or are intolerant to ≥2 lines of systemic therapy.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/30/2025

Locations: UC Irvine Health, Orange, California +10 locations

Conditions: B-cell Malignancy, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Waldenstrom Macroglobulinemia, Mantle Cell Lymphoma, Marginal Zone Lymphoma, Follicular Lymphoma, Non-Hodgkin Lymphoma

Learn More ›

Zanubrutinib, Bendamustine, Rituximab Prev. Untreated WM

NCT06561347

Recruiting

The purpose of this study is to determine the very good partial response (VGPR) or better rate in participants with Waldenström macroglobulinemia (WM). The names of the study drugs involved in this study are as follows: zanubrutinib, bendamustine, and rituximab.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/23/2025

Locations: Massachusetts General Hospital, Boston, Massachusetts +2 locations

Conditions: Waldenstrom Macroglobulinemia

Learn More ›

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib and Rituximab) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

NCT04840602

Recruiting

This phase II trial studies the effects of venetoclax and rituximab in comparison to ibrutinib and rituximab in treating patients with previously untreated Waldenstrom's macroglobulinemia/lymphoplasmacytic lymphoma. Ibrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Rituximab is a monoclonal antibody. It binds to a protein called CD20, which is found on B cells (a type of white blood cell) and some types of cancer cells. This may help the immune... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/23/2025

Locations: Banner University Medical Center - Tucson, Tucson, Arizona +111 locations

Banner University Medical Center - Tucson, Tucson, Arizona

University of Arizona Cancer Center-North Campus, Tucson, Arizona

Mayo Clinic in Florida, Jacksonville, Florida

Centralia Oncology Clinic, Centralia, Illinois

Carle at The Riverfront, Danville, Illinois

Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois

Carle Physician Group-Effingham, Effingham, Illinois

Crossroads Cancer Center, Effingham, Illinois

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois

Cancer Care Center of O'Fallon, O'Fallon, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Springfield Clinic, Springfield, Illinois

Springfield Memorial Hospital, Springfield, Illinois

Carle Cancer Center, Urbana, Illinois

Mary Greeley Medical Center, Ames, Iowa

McFarland Clinic - Ames, Ames, Iowa

McFarland Clinic - Boone, Boone, Iowa

McFarland Clinic - Trinity Cancer Center, Fort Dodge, Iowa

McFarland Clinic - Jefferson, Jefferson, Iowa

McFarland Clinic - Marshalltown, Marshalltown, Iowa

Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan

Trinity Health Medical Center - Brighton, Brighton, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Canton, Canton, Michigan

Trinity Health Medical Center - Canton, Canton, Michigan

Chelsea Hospital, Chelsea, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea, Michigan

Hematology Oncology Consultants-Clarkston, Clarkston, Michigan

Newland Medical Associates-Clarkston, Clarkston, Michigan

Henry Ford Hospital, Detroit, Michigan

Cancer Hematology Centers - Flint, Flint, Michigan

Genesee Hematology Oncology PC, Flint, Michigan

Genesys Hurley Cancer Institute, Flint, Michigan

Hurley Medical Center, Flint, Michigan

University of Michigan Health - Sparrow Lansing, Lansing, Michigan

Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan

Michigan Healthcare Professionals Pontiac, Pontiac, Michigan

Newland Medical Associates-Pontiac, Pontiac, Michigan

Trinity Health Saint Joseph Mercy Oakland Hospital, Pontiac, Michigan

MyMichigan Medical Center Saginaw, Saginaw, Michigan

Oncology Hematology Associates of Saginaw Valley PC, Saginaw, Michigan

MyMichigan Medical Center Tawas, Tawas City, Michigan

Huron Gastroenterology PC, Ypsilanti, Michigan

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti, Michigan

Mayo Clinic in Rochester, Rochester, Minnesota

Saint Francis Medical Center, Cape Girardeau, Missouri

Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri

Heartland Regional Medical Center, Saint Joseph, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Mercy Hospital South, Saint Louis, Missouri

Siteman Cancer Center-South County, Saint Louis, Missouri

Siteman Cancer Center at Christian Hospital, Saint Louis, Missouri

Siteman Cancer Center at Saint Peters Hospital, Saint Peters, Missouri

Saint Vincent Frontier Cancer Center, Billings, Montana

Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey

Memorial Sloan Kettering Monmouth, Middletown, New Jersey

Memorial Sloan Kettering Bergen, Montvale, New Jersey

Memorial Sloan Kettering Commack, Commack, New York

Glens Falls Hospital, Glens Falls, New York

Memorial Sloan Kettering Westchester, Harrison, New York

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

University of Rochester, Rochester, New York

Memorial Sloan Kettering Nassau, Uniondale, New York

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Southeastern Medical Oncology Center-Clinton, Clinton, North Carolina

Levine Cancer Institute-Gaston, Gastonia, North Carolina

Southeastern Medical Oncology Center-Goldsboro, Goldsboro, North Carolina

Southeastern Medical Oncology Center-Jacksonville, Jacksonville, North Carolina

Strecker Cancer Center-Belpre, Belpre, Ohio

Adena Regional Medical Center, Chillicothe, Ohio

Mount Carmel East Hospital, Columbus, Ohio

Columbus Oncology and Hematology Associates Inc, Columbus, Ohio

Riverside Methodist Hospital, Columbus, Ohio

Grant Medical Center, Columbus, Ohio

The Mark H Zangmeister Center, Columbus, Ohio

Mount Carmel Health Center West, Columbus, Ohio

Doctors Hospital, Columbus, Ohio

Delaware Health Center-Grady Cancer Center, Delaware, Ohio

Grady Memorial Hospital, Delaware, Ohio

Dublin Methodist Hospital, Dublin, Ohio

Central Ohio Breast and Endocrine Surgery, Gahanna, Ohio

Mount Carmel Grove City Hospital, Grove City, Ohio

Fairfield Medical Center, Lancaster, Ohio

Saint Rita's Medical Center, Lima, Ohio

OhioHealth Mansfield Hospital, Mansfield, Ohio

Marietta Memorial Hospital, Marietta, Ohio

OhioHealth Marion General Hospital, Marion, Ohio

Knox Community Hospital, Mount Vernon, Ohio

Licking Memorial Hospital, Newark, Ohio

Newark Radiation Oncology, Newark, Ohio

Mercy Health - Perrysburg Hospital, Perrysburg, Ohio

Southern Ohio Medical Center, Portsmouth, Ohio

Mercy Health - Saint Vincent Hospital, Toledo, Ohio

Mercy Health - Saint Anne Hospital, Toledo, Ohio

Saint Ann's Hospital, Westerville, Ohio

Genesis Healthcare System Cancer Care Center, Zanesville, Ohio

Providence Cancer Institute Clackamas Clinic, Clackamas, Oregon

Providence Newberg Medical Center, Newberg, Oregon

Providence Willamette Falls Medical Center, Oregon City, Oregon

Providence Portland Medical Center, Portland, Oregon

Providence Saint Vincent Medical Center, Portland, Oregon

Swedish Cancer Institute-Edmonds, Edmonds, Washington

Swedish Cancer Institute-Issaquah, Issaquah, Washington

Swedish Medical Center-First Hill, Seattle, Washington

Marshfield Medical Center-EC Cancer Center, Eau Claire, Wisconsin

Gundersen Lutheran Medical Center, La Crosse, Wisconsin

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Marshfield Medical Center - Minocqua, Minocqua, Wisconsin

Marshfield Medical Center-Rice Lake, Rice Lake, Wisconsin

Marshfield Medical Center-River Region at Stevens Point, Stevens Point, Wisconsin

Marshfield Medical Center - Weston, Weston, Wisconsin

Conditions: Lymphoplasmacytic Lymphoma, Waldenstrom Macroglobulinemia

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Study of SGR-1505 in Mature B-Cell Neoplasms

NCT05544019

Recruiting

The purpose of this study is to evaluate safety and tolerability and to determine the maximum tolerated dose (MTD) or maximum administered dose (MAD) and/or recommended dose (RD) of SGR-1505.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/22/2025

Locations: Banner Health - MD Anderson Cancer Center, Gilbert, Arizona +35 locations

Banner Health - MD Anderson Cancer Center, Gilbert, Arizona

Christiana Care Hospital - Helen F Graham Cancer Center, Newark, Delaware

Napa Research, Pompano Beach, Florida

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Regional Cancer Care Associates, Hackensack, New Jersey

Montefiore Medical Center, Bronx, New York

Roswell Park Comprehensive Cancer Center, Buffalo, New York

Weill Cornell, New York City, New York

Duke University, Durham, North Carolina

Gabrail Cancer & Research Center, Canton, Ohio

The Ohio State University - The James Cancer Hospital, Columbus, Ohio

Oregon Health and Science University - Knight Cancer Institute, Portland, Oregon

Rhode Island Hospital, Providence, Rhode Island

University of Texas Southwestern, Dallas, Texas

Fred Hutchinson Cancer Center, Seattle, Washington

Medical College of Wisconsin, Milwaukee, Wisconsin

AP-HP Hôpital Henri-Mondor, Créteil, Not set

Institut Gustave Roussy, Villejuif, Not set

Azienda Ospedaliera Nazionale SS. Antonio e Biagio e C. Arrigo - Presidio Ospedaliero SS Antonio e Biagio e Cesare Arrigo, Ospedale Civile, Alessandria, Not set

ASST Grande Ospedale Metropolitano Niguarda, Milano, Not set

IRCCS Ospedale San Raffaele, Milano, Not set

AOU Citta della Salute e della Scienza di Torino - Ospedale le Molinette, Torino, Not set

Azienda Ospedaliera - Universitaria Integrata di Verona - Ospedale Borgo Roma, Verona, Not set

Institute of Oncology, ARENSIA Exploratory Medicine, Chisinau, Not set

Uniwersyteckie Centrum Kliniczne, Osrodek Badan Klinicznych Wczesnych Faz, Gdańsk, Not set

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie, Warszawa, Not set

Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Lodzi, Łódź, Not set

ARENSIA Institutul Oncologic Prof. Dr. Alexandru Trestioreanu Bucuresti, Bucharest, Not set

ARENSIA Institutul Oncologic Prof. Dr. Ion Chiricuta Cluj Napoca, Cluj-Napoca, Not set

Institut Catala d'Oncologia - L'Hospitalet, Barcelona, Not set

Hospital Universitario Quironsalud Madrid, Madrid, Not set

START Madrid - CIOCC, Madrid, Not set

START Madrid - Hospital Fundacion Jimenez Diaz, Madrid, Not set

Clinica Universidad de Navarra - Pamplona, Pamplona, Not set

Hospital Clinico Universitario de Salamanca, Salamanca, Not set

ARENSIA Research Clinic at Harmony Health Clinic, Kyiv, Not set

Conditions: Mature B-Cell Neoplasm, Non Hodgkin Lymphoma, DLBCL, Waldenstrom Macroglobulinemia, MALT Lymphoma, Follicular Lymphoma, Pediatric-Type Follicular Lymphoma, IRF4 Gene Rearrangement, EBV-Positive DLBCL, Nos, Burkitt Lymphoma, Plasmablastic Lymphoma, High-grade B-cell Lymphoma, Primary Cutaneous Follicle Center Lymphoma, Primary Effusion Lymphoma, Mantle Cell Lymphoma, DLBCL Germinal Center B-Cell Type, Primary Mediastinal Large B Cell Lymphoma, T-Cell/Histiocyte Rich Lymphoma, ALK-Positive Large B-Cell Lymphoma, Primary Cutaneous Diffuse Large B-Cell Lymphoma, Splenic Marginal Zone Lymphoma, Chronic Lymphocytic Leukemia, Nodal Marginal Zone Lymphoma, HHV8-Positive DLBCL, Nos, Lymphoplasmacytic Lymphoma, Duodenal-Type Follicular Lymphoma

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A Study to Investigate Efficacy and Safety of BCL2 Inhibitor Sonrotoclax as Monotherapy and in Combination With Zanubrutinib in Adults With Waldenström Macroglobulinemia

NCT05952037

Recruiting

This study will evaluate the safety and efficacy of the BCL2 inhibitor sonrotoclax (BGB-11417) in participants with relapsed/refractory Waldenström's Macroglobulinemia (R/R WM) and in combination with zanubrutinib in adult participants with previously untreated WM.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/03/2025

Locations: City of Hope National Medical Center, Duarte, California +71 locations

City of Hope National Medical Center, Duarte, California

Colorado Blood Cancer Institute, Denver, Colorado

Medstar Georgetown University Hospital, Washington, District of Columbia

University of Miami, Miami, Florida

Northwestern Medicine Cancer Center, Warrenville, Illinois

Mission Cancer and Blood, Waukee, Iowa

University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, Maryland

Dana Farber Cancer Institute, Boston, Massachusetts

Mayo Clinic Rochester, Rochester, Minnesota

Hattiesburg Hematology and Oncology Clinic, Hattiesburg, Mississippi

Memorial Sloan Kettering Cancer Center Mskcc, New York, New York

Atrium Health Levine Cancer Institute (Lci), Charlotte, North Carolina

Ohio State University Comprehensive Cancer Center, Columbus, Ohio

Ut Southwestern Medical Center, Dallas, Texas

Huntsman Cancer Institute, Salt Lake City, Utah

Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia

University of Washington, Seattle, Washington

Concord Repatriation General Hospital, Concord, New South Wales

Genesiscare North Shore, St Leonards, New South Wales

Princess Alexandra Hospital, Woolloongabba, Queensland

Flinders Medical Centre, Bedford PK, South Australia

Monash Health, Clayton, Victoria

St Vincents Hospital Melbourne, Fitzroy, Victoria

Linear Clinical Research, Nedlands, Western Australia

Royal Perth Hospital, Perth, Western Australia

Cross Cancer Institute, Edmonton, Alberta

Lions Gate Hospital Chemotherapy Clinic, North Vancouver, British Columbia

Qeii Health Science Center, Halifax, Nova Scotia

Princess Margaret Cancer Centre, Toronto, Ontario

The First Affiliated Hospital of Xiamen University, Xiamen, Fujian

Guangdong Provincial Peoples Hospital, Guangzhou, Guangdong

Henan Cancer Hospital, Zhengzhou, Henan

Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei

Yancheng First Peoples Hospital, Yancheng, Jiangsu

Shengjing Hospital of China Medical Universityshenbei Branch, Shenyang, Liaoning

The Affiliated Hospital of Qingdao University Branch South, Qingdao, Shandong

Affiliated Zhongshan Hospital of Fudan University, Shanghai, Shanghai

The Third Peoples Hospital of Datong, Datong, Shanxi

Institute of Hematology and Hospital of Blood Disease, Tianjin, Tianjin

The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang

The First Hospital of Jiaxing, Jiaxing, Zhejiang

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang

Centre Hospitalier Universitaire Damiens Hopital Sud, Amiens Cedex, Not set

Chu Clermont Ferrand Therapie Cellulaire and Hematolo, Clermontferrand, Not set

Institut Paoli Calmettes, Marseille, Not set

Hopital de La Pitie Salpetriere, Paris, Not set

Chu Hopital Lyon Sud, PierreBenite, Not set

Hopital Robert Debre, Reims, Not set

General Hospital of Athens Alexandra, Athens, Not set

Irccs Azienda Ospedaliero Universitaria Bologna, Bologna, Not set

Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia, Brescia, Not set

Istituto Europeo Di Oncologia, Milano, Not set

Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda, Milano, Not set

Irccs Policlinico San Matteo, Universita Degli Studi Di Pavi, Pavia, Not set

Fondazione Policlinico Universitario Agostino Gemelli, Roma, Not set

Azienda Sanitaria Universitaria Friuli Centrale Presidio Ospedaliero Universitario Santa Maria Del, Udine, Not set

Hospital Universitario Vall Dhebron, Barcelona, Not set

Institut Catala Doncologia, Barcelona, Not set

Hospital Clinic de Barcelona, Barcelona, Not set

Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set

Hospital Universitario de Salamanca, Salamanca, Not set

Hospital Universitario Virgen Del Rocio, Sevilla, Not set

Hospital Universitari Mutua Terrassa, Terrassa, Not set

University Hospitals Dorset, Bournemouth, Not set

Beatson West of Scotland Cancer Centre, Glasgow, Not set

Churchill Hospital Oxford University Hospital Nhs Trust, Headington, Not set

Nhs Highland, Inverness, Not set

St Jamess University Hospital, Leeds, Not set

University College Hospital, London, Not set

The Christie Nhs Foundation Trust Manchester, Manchester, Not set

Plymouth Hospitals Nhs Trust, Plymouth, Not set

Royal Marsden Nhs Foundation Royal Marsden Hospital, Sutton, Not set

Conditions: Waldenstrom Macroglobulinemia, Waldenstrom's Macroglobulinemia Recurrent, Waldenstrom's Macroglobulinemia Refractory

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Combating Cancer-Related Fatigue: A Personalized Supportive Care Program

NCT06860880

Recruiting

This health services study will assess a multidisciplinary intervention program directed at fatigue mitigation among patients diagnosed with indolent lymphomas. Specifically, 30 subjects with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and 10 subjects with Follicular Lymphoma (FL), marginal zone lymphoma (MZL), lymphoplasmacytic lymphoma (LPL), Waldenström's Macroglobulinemia, or Cutaneous T Cell Lymphoma (CTCL) will be included.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/25/2025

Locations: North Carolina Basnight Cancer Hospital, Chapel Hill, North Carolina

Conditions: Indolent Lymphomas, Lymphoma, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Follicular Lymphoma, Marginal Zone Lymphoma, Lymphoplasmacytic Lymphoma, Waldenstrom Macroglobulinemia, Cutaneous T Cell Lymphoma

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Loncastuximab Tesirine in WM

NCT05190705

Recruiting

This study is being done to examine the safety and effectiveness of loncastuximab tesirine as a possible treatment for participants with Waldenström Macroglobulinemia (WM). The name of the study drug involved in this study is: * Loncastuximab tesirine

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/20/2025

Locations: Dana Farber Cancer Institute, Boston, Massachusetts +3 locations

Conditions: Waldenstrom Macroglobulinemia

Learn More ›

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