The state of North Carolina currently has 6 active clinical trials seeking participants for Narcolepsy research studies. These trials are conducted in various cities, including Durham, Winston-Salem, Charlotte and Chapel Hill.
A Switch Study From High-Sodium Oxybate to XYWAV to Evaluate Changes in Blood Pressure in Participants With Narcolepsy
Recruiting
The aim of this study is to quantify the change in blood pressure when participants with narcolepsy treated with high-sodium oxybate are transitioned to XYWAV, a low-sodium oxybate. The results of this study may provide health care providers (HCPs), patients, and payers with important new information regarding BP changes related to differences in sodium content between available oxybates for the treatment of narcolepsy.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
06/18/2024
Locations: Advanced Respiratory and Sleep Medicine, PLLC, Huntersville, North Carolina +1 locations
Conditions: Narcolepsy
SUNOSI® (Solriamfetol) Pregnancy Registry
Recruiting
The SUNOSI (solriamfetol) Pregnancy Registry is a prospective, multi-country, observational study to evaluate the safety of solriamfetol exposure during pregnancy in women with a diagnosis of narcolepsy or obstructive sleep apnea (OSA).
Gender:
Female
Ages:
All
Trial Updated:
05/09/2024
Locations: Evidera, a PPD business unit, Morrisville, North Carolina +1 locations
Conditions: Narcolepsy, Obstructive Sleep Apnea, Pregnant Women and Their Offspring
A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With Narcolepsy Type 1 (ALKS 2680-201)
Recruiting
The purpose of this research study is to assess the safety and efficacy of ALKS 2680 compared to placebo, including whether participants taking ALKS 2680 experience a greater decrease in sleepiness and a decrease in cataplexy ("sudden loss of muscle control"), compared to participants taking placebo alone.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/07/2024
Locations: Alkermes Investigational Site, Huntersville, North Carolina
Conditions: Narcolepsy Type 1
Ph4 PSG Combined JZP258-407
Recruiting
This study will assess the safety and efficacy of JZP258 (XYWAV) on sleepiness, polysomnography, and functional outcomes in patients with idiopathic hypersomnia (IH) or narcolepsy.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/29/2024
Locations: Clinical Research of Gastonia, Gastonia, North Carolina +1 locations
Conditions: Idiopathic Hypersomnia, Narcolepsy
A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions
Recruiting
The main aim is to evaluate the safety and tolerability of TAK-861 on participants with type 1 and type 2 narcolepsy from previous parent studies, TAK-861-2001 (NCT05687903) and TAK-861-2002 (NCT05687916).
Gender:
All
Ages:
Between 16 years and 70 years
Trial Updated:
02/15/2024
Locations: Research Carolina Elite, Denver, North Carolina +1 locations
Conditions: Narcolepsy Type 1, Narcolepsy Type 2
WAKIX® (Pitolisant) Pregnancy Registry
Recruiting
The WAKIX (pitolisant) Pregnancy Registry is a US-based, prospective, observational cohort study designed to evaluate the association between pitolisant exposure during pregnancy and subsequent maternal, fetal, and infant outcomes.
Gender:
Female
Ages:
All
Trial Updated:
01/24/2024
Locations: Evidera (PPD), Morrisville, North Carolina
Conditions: Pregnancy Related, Narcolepsy