There are currently 7 active clinical trials seeking participants for Cardiac Disease research studies. The states with the highest number of trials for Cardiac Disease participants are New York, Ontario, California and Ohio.
ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE
NCT05746559
Recruiting
The primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the clinical consequences of AKI (MAKE) at 90 days in adult participants with CKD who undergo non-emergent cardiac surgery with CPB.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
06/17/2024
Locations: Research Site, Tucson, Arizona +177 locations
Conditions: Chronic Kidney Disease, CKD, Cardiac Disease, Cardiopulmonary Bypass
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Cardiac Performance System Data Collection Study - Minnesota
NCT06149143
Recruiting
Non-significant risk device study to conduct evaluation of the performance of new device for monitoring of cardiac function (based on previous iterations 510(k) 173156)
Gender:
All
Ages:
22 years and above
Trial Updated:
04/15/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Cardiac Disease
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Fresh Autologous Whole Blood Transfusion After Cardiopulmonary Bypass
NCT03204357
Recruiting
Autologous blood transfused at the end of cardiopulmonary bypass will reduce total blood loss 24 hours after surgery and improve mitochondrial oxygen delivery measured by plasma succinate levels. The study design is a prospective randomized interventional trial of transfusion of fresh autologous whole blood versus standard of care expectant management of bleeding during elective cardiac surgery.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
03/19/2024
Locations: University of Colorado Hospital, Aurora, Colorado
Conditions: Cardiac Disease, Bleeding Postoperative
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Cardiac Performance System Data Collection Study
NCT05866666
Recruiting
Non-significant risk device study to conduct evaluation of the performance of new device for monitoring of cardiac function (based on previous iterations 510(k) 173156)
Gender:
All
Ages:
22 years and above
Trial Updated:
11/20/2023
Locations: Orlando Health, Orlando, Florida
Conditions: Cardiac Disease
Register for Updates
Paravertebral Block to Reduce the Incidence of New Onset Atrial Fibrillation After Cardiac Surgery
NCT04472299
Recruiting
The purpose if this pilot study is to determine if a perioperative infusion of 0.2% ropivacaine via bilateral T3 paravertebral catheters can decrease the incidence of new onset atrial fibrillation following primary CABG and/or valve surgery and compare a number of secondary outcomes.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/03/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: New Onset Atrial Fibrillation, Anesthesia, Local, Cardiac Disease
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Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)
NCT05055830
Recruiting
OPTIC is a prospective, open-label, non-randomized study of multiple medications administered to approximately 2000 children in the pediatric cardiac intensive care unit (PCICU) per routine clinical car by their treating provider. The purpose of this study is to characterize the PK of drugs routinely administered to children per standard of care using opportunistic and scavenged samples. The prescribing of drugs to children will not be part of this protocol. After the child/adult (<21 years of... Read More
Gender:
All
Ages:
Between 0 months and 20 years
Trial Updated:
09/25/2023
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: Cardiac Disease, Critically Ill, Children, Adult
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Cardiovascular Structure and Function in the Mucopolysaccharidoses
NCT05063435
Recruiting
This study's investigators previously demonstrated the potential utility of non-invasive carotid ultrasonography to calculate carotid intima media thickness (cIMT) and stiffness (as measured by the three parameters, carotid cross-sectional distensibility [cCSD], carotid cross-sectional compliance [cCSC], and carotid incremental elastic modulus [cIEM]) in people with mucopolysaccharidoses (MPS). Investigators also studied arterial gene expression in animal models of MPS, and identified upregulat... Read More
Gender:
All
Ages:
All
Trial Updated:
08/28/2023
Locations: Children's Hospital of Orange County, Orange, California
Conditions: Mucopolysaccharidoses, Carotid Disease, Cardiac Disease, Inflammation
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